Stability of the Influenza Virus Hemagglutinin Protein Correlates with Evolutionary Dynamics

por Eili Y. Klein, Deena Blumenkrantz, Adrian Serohijos, Eugene Shakhnovich, Jeong-Mo Choi, João V. Rodrigues, Brendan D. Smith, Andrew P. Lane, Andrew Feldman, Andrew Pekosz
Publicado 2018

Binding of the von Willebrand Factor A Domain of Capillary Morphogenesis Protein 2 to Anthrax Protective Antigen Vaccine Reduces Immunogenicity in Mice

por Fabiana Freire Mendes de Oliveira, Sireesha Mamillapalli, Srinivas Gonti, Robert N. Brey, Han Li, Jarad Schiffer, Arturo Casadevall, James G. Bann
Publicado 2020

Phosphorylation and Proteasome Recognition of the mRNA-Binding Protein Cth2 Facilitates Yeast Adaptation to Iron Deficiency

por Antonia M. Romero, Mar Martínez-Pastor, Gang Du, Carme Solé, María Carlos, Sandra V. Vergara, Nerea Sanvisens, James A. Wohlschlegel, David P. Toczyski, Francesc Posas, Eulàlia de Nadal, María T. Martínez-Pastor, Dennis J. Thiele, Sergi Puig
Publicado 2018

The Impact of Redox, Hydrolysis and Dehydration Chemistry on the Structural and Magnetic Properties of Magnetoferritin Prepared in Variable Thermal Conditions

por Lucia Balejčíková, Karel Saksl, Jozef Kováč, Anne Martel, Vasil M. Garamus, Mikhail V. Avdeev, Viktor I. Petrenko, László Almásy, Peter Kopčanský
Publicado 2021

Emergence and Enhancement of Ultrasensitivity through Posttranslational Modulation of Protein Stability

por Carla M. Kumbale, Eberhard O. Voit, Qiang Zhang
Publicado 2021

Enhanced Replication of Mouse Adenovirus Type 1 following Virus-Induced Degradation of Protein Kinase R (PKR)

por Danielle E. Goodman, Carla D. Pretto, Tomas A. Krepostman, Kelly E. Carnahan, Katherine R. Spindler
Publicado 2019

A Thermodynamic Model for Interpreting Tryptophan Excitation-Energy-Dependent Fluorescence Spectra Provides Insight Into Protein Conformational Sampling and Stability

por A Kwok, IS Camacho, S Winter, M Knight, RM Meade, MW Van der Kamp, A Turner, J O’Hara, JM Mason, AR Jones, VL Arcus, CR Pudney, CR Pudney
Publicado 2021

A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions

por Zishuo Cheng, Ben A. Shurina, Christopher R. Bethel, Pei W. Thomas, Steven H. Marshall, Caitlyn A. Thomas, Kundi Yang, Robert L. Kimble, Jonathan S. Montgomery, Matthew G. Orischak, Callie M. Miller, Jordan L. Tennenbaum, Jay C. Nix, David L. Tierney, Walter Fast, Robert A. Bonomo, Richard C. Page, Michael W. Crowder
Publicado 2019

Structure and in silico simulations of a cold-active esterase reveals its prime cold-adaptation mechanism

por Nehad Noby, Husam Sabah Auhim, Samuel Winter, Harley L. Worthy, Amira M. Embaby, Hesham Saeed, Ahmed Hussein, Christopher R. Pudney, Pierre J. Rizkallah, Stephen A. Wells, D. Dafydd Jones
Publicado 2021

The Impact of Glycerol on an Affibody Conformation and Its Correlation to Chemical Degradation

por Ingrid Ramm, Adrian Sanchez-Fernandez, Jaeyeong Choi, Christian Lang, Jonas Fransson, Herje Schagerlöf, Marie Wahlgren, Lars Nilsson
Publicado 2021

KIF15 Promotes Progression of Castration Resistant Prostate Cancer by Activating EGFR Signaling Pathway

por Lin Gao, Ru Zhao, Junmei Liu, Wenbo Zhang, Feifei Sun, Qianshuo Yin, Xin Wang, Meng Wang, Tingting Feng, Yiming Qin, Wenjie Cai, Qianni Li, Hanchen Dong, Xueqing Chen, Xueting Xiong, Hui Liu, Hui Liu, Jing Hu, Jing Hu, Weiwen Chen, Bo Han, Bo Han
Publicado 2021

Optimization of Hemoglobin Encapsulation within PLGA Nanoparticles and Their Investigation as Potential Oxygen Carriers

por Clara Coll-Satue, Michelle Maria Theresia Jansman, Peter Waaben Thulstrup, Leticia Hosta-Rigau
Publicado 2021

UBCH5 Family Members Differentially Impact Stabilization of Mutant p53 via RNF128 Iso1 During Barrett’s Progression to Esophageal AdenocarcinomaSummary

por Paramita Ray, Derek J. Nancarrow, Daysha Ferrer-Torres, Zhuwen Wang, May San Martinho, Tonaye Hinton, Joshua H. Wu, Angeline Wu, Danielle Kim Turgeon, Max A. Hammer, Michael K. Dame, Theodore S. Lawrence, Patrick J. O’Brien, Jason R. Spence, David G. Beer, Dipankar Ray
Publicado 2022

Pathogenic D76N Variant of β₂-Microglobulin: Synergy of Diverse Effects in Both the Native and Amyloid States

por Éva Bulyáki, Judit Kun, Tamás Molnár, Alexandra Papp, András Micsonai, Henrietta Vadászi, Borbála Márialigeti, Attila István Kovács, Gabriella Gellén, Keiichi Yamaguchi, Yuxi Lin, Masatomo So, Mihály Józsi, Gitta Schlosser, Young-Ho Lee, Károly Liliom, Yuji Goto, József Kardos
Publicado 2021

PARP1 PARylates and stabilizes STAT5 in FLT3-ITD acute myeloid leukemia and other STAT5-activated cancers

por Anna J. Dellomo, Rachel Abbotts, Christian L. Eberly, Mariusz Karbowski, Maria R. Baer, Tami J. Kingsbury, Feyruz V. Rassool
Publicado 2022