How the spleen reshapes and retains young and old red blood cells: A computational investigation.

por He Li, Zixiang Leonardo Liu, Lu Lu, Pierre Buffet, George Em Karniadakis
Publicado 2021

A modular approach for modeling the cell cycle based on functional response curves.

por Jolan De Boeck, Jan Rombouts, Lendert Gelens
Publicado 2021

Optimal drug synergy in antimicrobial treatments.

por Joseph Peter Torella, Remy Chait, Roy Kishony
Publicado 2010

Ten simple rules for Global North researchers to stop perpetuating helicopter research in the Global South.

por Danny Haelewaters, Tina A Hofmann, Adriana L Romero-Olivares
Publicado 2021

Integration of a physiologically-based pharmacokinetic model with a whole-body, organ-resolved genome-scale model for characterization of ethanol and acetaldehyde metabolism.

por Leo Zhu, William Pei, Ines Thiele, Radhakrishnan Mahadevan
Publicado 2021

Eliminating accidental deviations to minimize generalization error and maximize replicability: Applications in connectomics and genomics.

por Eric W Bridgeford, Shangsi Wang, Zeyi Wang, Ting Xu, Cameron Craddock, Jayanta Dey, Gregory Kiar, William Gray-Roncal, Carlo Colantuoni, Christopher Douville, Stephanie Noble, Carey E Priebe, Brian Caffo, Michael Milham, Xi-Nian Zuo, Consortium for Reliability and Reproducibility, Joshua T Vogelstein
Publicado 2021

Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge.

por Zhaoping Xiong, Minji Jeon, Robert J Allaway, Jaewoo Kang, Donghyeon Park, Jinhyuk Lee, Hwisang Jeon, Miyoung Ko, Hualiang Jiang, Mingyue Zheng, Aik Choon Tan, Xindi Guo, Multi-Targeting Drug DREAM Challenge Community, Kristen K Dang, Alex Tropsha, Chana Hecht, Tirtha K Das, Heather A Carlson, Ruben Abagyan, Justin Guinney, Avner Schlessinger, Ross Cagan
Publicado 2021

Modelling the spatial and temporal constrains of the GABAergic influence on neuronal excitability.

por Aniello Lombardi, Heiko J Luhmann, Werner Kilb
Publicado 2021

Networks of Causal Linkage Between Eigenmodes Characterize Behavioral Dynamics of Caenorhabditis elegans.

por Erik Saberski, Antonia K Bock, Rachel Goodridge, Vitul Agarwal, Tom Lorimer, Scott A Rifkin, George Sugihara
Publicado 2021

Validation of DBFOLD: An efficient algorithm for computing folding pathways of complex proteins.

por Amir Bitran, William M Jacobs, Eugene Shakhnovich
Publicado 2020

ASCENT (Automated Simulations to Characterize Electrical Nerve Thresholds): A pipeline for sample-specific computational modeling of electrical stimulation of peripheral nerves.

por Eric D Musselman, Jake E Cariello, Warren M Grill, Nicole A Pelot
Publicado 2021

Evidence from simulation studies for selective constraints on the codon usage of the Angiosperm psbA gene.

por Antonina Kalkus, Joy Barrett, Theyjasvi Ashok, Brian R Morton
Publicado 2021

Novel peptide-mediated interactions derived from high-resolution 3-dimensional structures.

por Amelie Stein, Patrick Aloy
Publicado 2010

CAMAP: Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation.

por Tariq Daouda, Maude Dumont-Lagacé, Albert Feghaly, Yahya Benslimane, Rébecca Panes, Mathieu Courcelles, Mohamed Benhammadi, Lea Harrington, Pierre Thibault, François Major, Yoshua Bengio, Étienne Gagnon, Sébastien Lemieux, Claude Perreault
Publicado 2021

Hemodynamics-driven mathematical model of first and second heart sound generation.

por Mehrdad Shahmohammadi, Hongxing Luo, Philip Westphal, Richard N Cornelussen, Frits W Prinzen, Tammo Delhaas
Publicado 2021

Ten simple rules for being a faculty advocate of first-year graduate students.

por Kevin A Janes
Publicado 2021

Computational analysis of GAL pathway pinpoints mechanisms underlying natural variation.

por Jiayin Hong, Julius Palme, Bo Hua, Michael Springer
Publicado 2021

The interplay between vaccination and social distancing strategies affects COVID19 population-level outcomes.

por Sharon Guerstein, Victoria Romeo-Aznar, Ma'ayan Dekel, Oren Miron, Nadav Davidovitch, Rami Puzis, Shai Pilosof
Publicado 2021

Conventional measures of intrinsic excitability are poor estimators of neuronal activity under realistic synaptic inputs.

por Adrienn Szabó, Katalin Schlett, Attila Szücs
Publicado 2021

Transcriptomic entropy benchmarks stem cell-derived cardiomyocyte maturation against endogenous tissue at single cell level.

por Suraj Kannan, Michael Farid, Brian L Lin, Matthew Miyamoto, Chulan Kwon
Publicado 2021