Reduced C9orf72 function leads to defective synaptic vesicle release and neuromuscular dysfunction in zebrafish

por Zoé Butti, Yingzhou Edward Pan, Jean Giacomotto, Shunmoogum A. Patten
Publicado 2021

Immunological considerations and challenges for regenerative cellular therapies

por Sandra Petrus-Reurer, Marco Romano, Sarah Howlett, Joanne Louise Jones, Giovanna Lombardi, Kourosh Saeb-Parsy
Publicado 2021

Androgen receptor variant shows heterogeneous expression in prostate cancer according to differentiation stage

por Ada Gjyrezi, Giuseppe Galletti, Jiaren Zhang, Daniel Worroll, Michael Sigouros, Seaho Kim, Victoria Cooley, Karla V. Ballman, Allyson J. Ocean, Manish A. Shah, Joseph M. Scandura, Andrea Sboner, David M. Nanus, Himisha Beltran, Scott Tagawa, Paraskevi Giannakakou
Publicado 2021

An in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients

por Anne C. Gilmore, Sarah J. Flaherty, Veena Somasundaram, David A. Scheiblin, Stephen J. Lockett, David A. Wink, William F. Heinz
Publicado 2021

Actin crosslinker competition and sorting drive emergent GUV size-dependent actin network architecture

por Yashar Bashirzadeh, Steven A. Redford, Chatipat Lorpaiboon, Alessandro Groaz, Hossein Moghimianavval, Thomas Litschel, Petra Schwille, Glen M. Hocky, Aaron R. Dinner, Allen P. Liu
Publicado 2021

In vitro CSC-derived cardiomyocytes exhibit the typical microRNA-mRNA blueprint of endogenous cardiomyocytes

por Mariangela Scalise, Fabiola Marino, Luca Salerno, Teresa Mancuso, Donato Cappetta, Antonella Barone, Elvira Immacolata Parrotta, Annalaura Torella, Domenico Palumbo, Pierangelo Veltri, Antonella De Angelis, Liberato Berrino, Francesco Rossi, Alessandro Weisz, Marcello Rota, Konrad Urbanek, Bernardo Nadal-Ginard, Daniele Torella, Eleonora Cianflone
Publicado 2021

Genetic variants associated with platelet count are predictive of human disease and physiological markers

por Evgenia Mikaelsdottir, Gudmar Thorleifsson, Lilja Stefansdottir, Gisli Halldorsson, Jon K. Sigurdsson, Sigrun H. Lund, Vinicius Tragante, Pall Melsted, Solvi Rognvaldsson, Kristjan Norland, Anna Helgadottir, Magnus K. Magnusson, Gunnar B. Ragnarsson, Sigurdur Y. Kristinsson, Sigrun Reykdal, Brynjar Vidarsson, Ingibjorg J. Gudmundsdottir, Isleifur Olafsson, Pall T. Onundarson, Olof Sigurdardottir, Emil L. Sigurdsson, Gerdur Grondal, Arni J. Geirsson, Gudmundur Geirsson, Julius Gudmundsson, Hilma Holm, Saedis Saevarsdottir, Ingileif Jonsdottir, Gudmundur Thorgeirsson, Daniel F. Gudbjartsson, Unnur Thorsteinsdottir, Thorunn Rafnar, Kari Stefansson
Publicado 2021

Author Correction: Accumulation of formaldehyde causes motor deficits in an in vivo model of hindlimb unloading

por Dandan Yao, Qingyuan He, Shangying Bai, Hang Zhao, Jun Yang, Dehua Cui, Yan Yu, Xuechao Fei, Yufei Mei, Ye Cheng, Shi Yan, Nayan Huang, Yalan Di, Xianjie Cai, Rui Wang, Yajuan Gao, Fangrao Cheng, Shengjie Zhao, Xu Yang, Xiang Cai, Hongbin Han, Jihui Lyu, Zhiqian Tong
Publicado 2021

Deep-coverage spatiotemporal proteome of the picoeukaryote Ostreococcus tauri reveals differential effects of environmental and endogenous 24-hour rhythms

por Holly Kay, Ellen Grünewald, Helen K. Feord, Sergio Gil, Sew Y. Peak-Chew, Alessandra Stangherlin, John S. O’Neill, Gerben van Ooijen
Publicado 2021

Invasive potential of tropical fruit flies in temperate regions under climate change

por Andrew Paul Gutierrez, Luigi Ponti, Markus Neteler, David Maxwell Suckling, José Ricardo Cure
Publicado 2021

Slow viral propagation during initial phase of infection leads to viral persistence in mice

por Haifeng C. Xu, Ruifeng Wang, Prashant V. Shinde, Lara Walotka, Anfei Huang, Gereon Poschmann, Jun Huang, Wei Liu, Kai Stühler, Heiner Schaal, Andreas Bergthaler, Aleksandra A. Pandyra, Cornelia Hardt, Karl S. Lang, Philipp A. Lang
Publicado 2021

Regulation of the immune tolerance system determines the susceptibility to HLA-mediated abacavir-induced skin toxicity

por Takeshi Susukida, Saki Kuwahara, Binbin Song, Akira Kazaoka, Shigeki Aoki, Kousei Ito
Publicado 2021

Single-cell RNA sequencing of human nail unit defines RSPO4 onychofibroblasts and SPINK6 nail epithelium

por Hyun Je Kim, Joon Ho Shim, Ji-Hye Park, Hyun Tae Shin, Jong Sup Shim, Kee-Taek Jang, Woong-Yang Park, Kyung-Hoon Lee, Eun Ji Kwon, Hyung-Suk Jang, Hanseul Yang, Jong Hee Lee, Jun-Mo Yang, Dongyoun Lee
Publicado 2021

Cervical transcutaneous vagal nerve stimulation (ctVNS) improves human cognitive performance under sleep deprivation stress

por Lindsey K. McIntire, R. Andy McKinley, Chuck Goodyear, John P. McIntire, Rebecca D. Brown
Publicado 2021

AGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division

por Vasiliki I. Pantazopoulou, Anastasios D. Delis, Stella Georgiou, Stamatis N. Pagakis, Vicky Filippa, Eleni Dragona, Ismini Kloukina, Elias Chatzitheodoridis, Jonel Trebicka, Athanassios D. Velentzas, Maja Thiele, Sarantis Gagos, Dimitris Thanos, Sofia Tseleni-Balafouta, Dimitrios J. Stravopodis, Ema Anastasiadou
Publicado 2021

Microglial metabolism is a pivotal factor in sexual dimorphism in Alzheimer’s disease

por Marie-Victoire Guillot-Sestier, Ana Rubio Araiz, Virginia Mela, Aline Sayd Gaban, Eoin O’Neill, Lisha Joshi, Edward T. Chouchani, Evanna L. Mills, Marina A. Lynch
Publicado 2021

Accessory proteins of the RAS-MAPK pathway: moving from the side line to the front line

por Silke Pudewell, Christoph Wittich, Neda S. Kazemein Jasemi, Farhad Bazgir, Mohammad R. Ahmadian
Publicado 2021

Placental secretome characterization identifies candidates for pregnancy complications

por Tina Napso, Xiaohui Zhao, Marta Ibañez Lligoña, Ionel Sandovici, Richard G. Kay, Amy L. George, Fiona M. Gribble, Frank Reimann, Claire L. Meek, Russell S. Hamilton, Amanda N. Sferruzzi-Perri
Publicado 2021

North Atlantic warming over six decades drives decreases in krill abundance with no associated range shift

por Martin Edwards, Pierre Hélaouët, Eric Goberville, Alistair Lindley, Geraint A. Tarling, Michael T. Burrows, Angus Atkinson
Publicado 2021

Control of impulsivity by Gi-protein signalling in layer-5 pyramidal neurons of the anterior cingulate cortex

por Bastiaan van der Veen, Sampath K. T. Kapanaiah, Kasyoka Kilonzo, Peter Steele-Perkins, Martin M. Jendryka, Stefanie Schulz, Bosiljka Tasic, Zizhen Yao, Hongkui Zeng, Thomas Akam, Janet R. Nicholson, Birgit Liss, Wiebke Nissen, Anton Pekcec, Dennis Kätzel
Publicado 2021