Targeted transcriptome analysis using synthetic long read sequencing uncovers isoform reprograming in the progression of colon cancer

por Silvia Liu, Indira Wu, Yan-Ping Yu, Michael Balamotis, Baoguo Ren, Tuval Ben Yehezkel, Jian-Hua Luo
Publicado 2021

Exploring the evidence for epigenetic regulation of environmental influences on child health across generations

por Carrie V. Breton, Remy Landon, Linda G. Kahn, Michelle Bosquet Enlow, Alicia K. Peterson, Theresa Bastain, Joseph Braun, Sarah S. Comstock, Cristiane S. Duarte, Alison Hipwell, Hong Ji, Janine M. LaSalle, Rachel L. Miller, Rashelle Musci, Jonathan Posner, Rebecca Schmidt, Shakira F. Suglia, Irene Tung, Daniel Weisenberger, Yeyi Zhu, Rebecca Fry
Publicado 2021

Targeting therapy-resistant lung cancer stem cells via disruption of the AKT/TSPYL5/PTEN positive-feedback loop

por In-Gyu Kim, Jei-Ha Lee, Seo-Yeon Kim, Chang-Kyu Heo, Rae-Kwon Kim, Eun-Wie Cho
Publicado 2021

CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells

por Ashley J. Clark, Niamh Mullooly, Dewi Safitri, Matthew Harris, Tessa de Vries, Antoinette MaassenVanDenBrink, David R. Poyner, Davide Gianni, Mark Wigglesworth, Graham Ladds
Publicado 2021

Auditory cortical micro-networks show differential connectivity during voice and speech processing in humans

por Florence Steiner, Marine Bobin, Sascha Frühholz
Publicado 2021

Guard cells control hypocotyl elongation through HXK1, HY5, and PIF4

por Gilor Kelly, Danja Brandsma, Aiman Egbaria, Ofer Stein, Adi Doron-Faigenboim, Nitsan Lugassi, Eduard Belausov, Hanita Zemach, Felix Shaya, Nir Carmi, Nir Sade, David Granot
Publicado 2021

Plant-soil feedbacks help explain biodiversity-productivity relationships

por Leslie E. Forero, Andrew Kulmatiski, Josephine Grenzer, Jeanette M. Norton
Publicado 2021

TGF-β-dependent reprogramming of amino acid metabolism induces epithelial–mesenchymal transition in non-small cell lung cancers

por Fumie Nakasuka, Sho Tabata, Takeharu Sakamoto, Akiyoshi Hirayama, Hiromichi Ebi, Tadaaki Yamada, Ko Umetsu, Maki Ohishi, Ayano Ueno, Hisatsugu Goto, Masahiro Sugimoto, Yasuhiko Nishioka, Yasuhiro Yamada, Masaru Tomita, Atsuo T. Sasaki, Seiji Yano, Tomoyoshi Soga
Publicado 2021

Childhood socioeconomic status is associated with psychometric intelligence and microstructural brain development

por Hikaru Takeuchi, Yasuyuki Taki, Kohei Asano, Michiko Asano, Yuko Sassa, Susumu Yokota, Yuka Kotozaki, Rui Nouchi, Ryuta Kawashima
Publicado 2021

Author Correction: Exploration of natural red-shifted rhodopsins using a machine learning-based Bayesian experimental design

por Keiichi Inoue, Masayuki Karasuyama, Ryoko Nakamura, Masae Konno, Daichi Yamada, Kentaro Mannen, Takashi Nagata, Yu Inatsu, Hiromu Yawo, Kei Yura, Oded Béjà, Hideki Kandori, Ichiro Takeuchi
Publicado 2021

Author Correction: Development of a functional salivary gland tissue chip with potential for high-content drug screening

por Yuanhui Song, Hitoshi Uchida, Azmeer Sharipol, Lindsay Piraino, Jared A. Mereness, Matthew H. Ingalls, Jonathan Rebhahn, Shawn D. Newlands, Lisa A. DeLouise, Catherine E. Ovitt, Danielle S. W. Benoit
Publicado 2021

Sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice

por John E. Schjenken, David J. Sharkey, Ella S. Green, Hon Yeung Chan, Ricky A. Matias, Lachlan M. Moldenhauer, Sarah A. Robertson
Publicado 2021

CellectSeq: In silico discovery of antibodies targeting integral membrane proteins combining in situ selections and next-generation sequencing

por Abdellali Kelil, Eugenio Gallo, Sunandan Banerjee, Jarrett J. Adams, Sachdev S. Sidhu
Publicado 2021

Author Correction: Submolecular probing of the complement C5a receptor–ligand binding reveals a cooperative two-site binding mechanism

por Andra C. Dumitru, R. N. V. Krishna Deepak, Heng Liu, Melanie Koehler, Cheng Zhang, Hao Fan, David Alsteens
Publicado 2021

Neutron reflectometry and NMR spectroscopy of full-length Bcl-2 protein reveal its membrane localization and conformation

por Ameeq Ul Mushtaq, Jörgen Ådén, Luke A. Clifton, Hanna Wacklin-Knecht, Mario Campana, Artur P. G. Dingeldein, Cecilia Persson, Tobias Sparrman, Gerhard Gröbner
Publicado 2021

Non-quaternary oximes detoxify nerve agents and reactivate nerve agent-inhibited human butyrylcholinesterase

por Gabriel Amitai, Alexander Plotnikov, Shira Chapman, Shlomi Lazar, Rellie Gez, Dan Loewenthal, Khriesto A. Shurrush, Galit Cohen, Leonardo J. Solmesky, Haim Barr, Alan J. Russell
Publicado 2021

Hybrid PET-MRI for early detection of dopaminergic dysfunction and microstructural degradation involved in Parkinson’s disease

por Song’an Shang, Daixin Li, Youyong Tian, Rushuai Li, Hongdong Zhao, Liyun Zheng, Yingdong Zhang, Yu-Chen Chen, Xindao Yin
Publicado 2021

Cyanocobalamin prevents cardiomyopathy in type 1 diabetes by modulating oxidative stress and DNMT-SOCS1/3-IGF-1 signaling

por Masao Kakoki, Purushotham V. Ramanathan, John R. Hagaman, Ruriko Grant, Jennifer C. Wilder, Joan M. Taylor, J. Charles Jennette, Oliver Smithies, Nobuyo Maeda-Smithies
Publicado 2021

A rice QTL GS3.1 regulates grain size through metabolic-flux distribution between flavonoid and lignin metabolons without affecting stress tolerance

por Yi-Min Zhang, Hong-Xiao Yu, Wang-Wei Ye, Jun-Xiang Shan, Nai-Qian Dong, Tao Guo, Yi Kan, You-Huang Xiang, Hai Zhang, Yi-Bing Yang, Ya-Chao Li, Huai-Yu Zhao, Zi-Qi Lu, Shuang-Qin Guo, Jie-Jie Lei, Ben Liao, Xiao-Rui Mu, Ying-Jie Cao, Jia-Jun Yu, Hong-Xuan Lin
Publicado 2021

Plasmodium metabolite HMBPP stimulates feeding of main mosquito vectors on blood and artificial toxic sources

por Viktoria E. Stromsky, Melika Hajkazemian, Elizabeth Vaisbourd, Raimondas Mozūraitis, S. Noushin Emami
Publicado 2021