A promiscuous ancestral enzyme´s structure unveils protein variable regions of the highly diverse metallo-β-lactamase family

por Pablo Perez-Garcia, Stefanie Kobus, Christoph G. W. Gertzen, Astrid Hoeppner, Nicholas Holzscheck, Christoph Heinrich Strunk, Harald Huber, Karl-Erich Jaeger, Holger Gohlke, Filip Kovacic, Sander H. J. Smits, Wolfgang R. Streit, Jennifer Chow
Publicado 2021

DeepLabStream enables closed-loop behavioral experiments using deep learning-based markerless, real-time posture detection

por Jens F. Schweihoff, Matvey Loshakov, Irina Pavlova, Laura Kück, Laura A. Ewell, Martin K. Schwarz
Publicado 2021

R–R–T (resistance–resilience–transformation) typology reveals differential conservation approaches across ecosystems and time

por Guillaume Peterson St-Laurent, Lauren E. Oakes, Molly Cross, Shannon Hagerman
Publicado 2021

Personalized immunoglobulin aptamers for detection of multiple myeloma minimal residual disease in serum

por Claudia Tapia-Alveal, Timothy R. Olsen, Tilla S. Worgall
Publicado 2020

In-vivo efficacy of biodegradable ultrahigh ductility Mg-Li-Zn alloy tracheal stents for pediatric airway obstruction

por Jingyao Wu, Leila J. Mady, Abhijit Roy, Ali Mübin Aral, Boeun Lee, Feng Zheng, Toma Catalin, Youngjae Chun, William R. Wagner, Ke Yang, Humberto E. Trejo Bittar, David Chi, Prashant N. Kumta
Publicado 2020

Brassicaceae transcriptomes reveal convergent evolution of super-accumulation of sinigrin

por Jinghua Yang, Zhangping Li, Jinmin Lian, Guoning Qi, Pibiao Shi, Jiawei He, Zhongyuan Hu, Mingfang Zhang
Publicado 2020

Gene co-expression in the interactome: moving from correlation toward causation via an integrated approach to disease module discovery

por Paola Paci, Giulia Fiscon, Federica Conte, Rui-Sheng Wang, Lorenzo Farina, Joseph Loscalzo
Publicado 2021

A cross-species assessment of behavioral flexibility in compulsive disorders

por Nabil Benzina, Karim N’Diaye, Antoine Pelissolo, Luc Mallet, Eric Burguière
Publicado 2021

Publisher Correction: Estimating and explaining the spread of COVID-19 at the county level in the USA

por Anthony R. Ives, Claudio Bozzuto
Publicado 2021

Coconut genome assembly enables evolutionary analysis of palms and highlights signaling pathways involved in salt tolerance

por Yaodong Yang, Stéphanie Bocs, Haikuo Fan, Alix Armero, Luc Baudouin, Pengwei Xu, Junyang Xu, Dominique This, Chantal Hamelin, Amjad Iqbal, Rashad Qadri, Lixia Zhou, Jing Li, Yi Wu, Zilong Ma, Auguste Emmanuel Issali, Ronan Rivallan, Na Liu, Wei Xia, Ming Peng, Yong Xiao
Publicado 2021

A chicken DNA methylation clock for the prediction of broiler health

por Günter Raddatz, Ryan J. Arsenault, Bridget Aylward, Rose Whelan, Florian Böhl, Frank Lyko
Publicado 2021

NTRK kinase domain mutations in cancer variably impact sensitivity to type I and type II inhibitors

por Romel Somwar, Nicolle E. Hofmann, Bryan Smith, Igor Odintsov, Morana Vojnic, Irina Linkov, Ashley Tam, Inna Khodos, Marissa S. Mattar, Elisa de Stanchina, Daniel Flynn, Marc Ladanyi, Alexander Drilon, Ujwal Shinde, Monika A. Davare
Publicado 2020

Biomolecular condensates as arbiters of biochemical reactions inside the nucleus

por Guillaume Laflamme, Karim Mekhail
Publicado 2020

Integrative multi-omics analysis of muscle-invasive bladder cancer identifies prognostic biomarkers for frontline chemotherapy and immunotherapy

por Qianxing Mo, Roger Li, Dennis O. Adeegbe, Guang Peng, Keith Syson Chan
Publicado 2020

Genetic ancestry, skin pigmentation, and the risk of cutaneous squamous cell carcinoma in Hispanic/Latino and non-Hispanic white populations

por Eric Jorgenson, Hélène Choquet, Jie Yin, Thomas J. Hoffmann, Yambazi Banda, Mark N. Kvale, Neil Risch, Catherine Schaefer, Maryam M. Asgari
Publicado 2020

Development of a sequencing system for spatial decoding of DNA barcode molecules at single-molecule resolution

por Yusuke Oguchi, Hirofumi Shintaku, Sotaro Uemura
Publicado 2020

Structurally distinct telomere-binding proteins in Ustilago maydis execute non-overlapping functions in telomere replication, recombination, and protection

por Eun Young Yu, Syed S. Zahid, Swapna Ganduri, Jeanette H. Sutherland, Min Hsu, William K. Holloman, Neal F. Lue
Publicado 2020

NAD+/NADH redox alterations reconfigure metabolism and rejuvenate senescent human mesenchymal stem cells in vitro

por Xuegang Yuan, Yijun Liu, Brent M. Bijonowski, Ang-Chen Tsai, Qin Fu, Timothy M. Logan, Teng Ma, Yan Li
Publicado 2020

Causal evidence for the adaptive benefits of social foraging in the wild

por Lysanne Snijders, Stefan Krause, Alan N. Tump, Michael Breuker, Chente Ortiz, Sofia Rizzi, Indar W. Ramnarine, Jens Krause, Ralf H.J.M. Kurvers
Publicado 2021

Author Correction: The origin of Rhinocerotoidea and phylogeny of Ceratomorpha (Mammalia, Perissodactyla)

por Bin Bai, Jin Meng, Chi Zhang, Yan-Xin Gong, Yuan-Qing Wang
Publicado 2021