Microfluidic chips provide visual access to in situ soil ecology

por Paola Micaela Mafla-Endara, Carlos Arellano-Caicedo, Kristin Aleklett, Milda Pucetaite, Pelle Ohlsson, Edith C. Hammer
Publicado 2021

Renin–angiotensin system impairs macrophage lipid metabolism to promote age-related macular degeneration in mouse models

por Norihiro Nagai, Hirohiko Kawashima, Eriko Toda, Kohei Homma, Hideto Osada, Naymel A. Guzman, Shinsuke Shibata, Yasuo Uchiyama, Hideyuki Okano, Kazuo Tsubota, Yoko Ozawa
Publicado 2020

Large genome-wide association study identifies three novel risk variants for restless legs syndrome

por Maria Didriksen, Muhammad Sulaman Nawaz, Joseph Dowsett, Steven Bell, Christian Erikstrup, Ole B. Pedersen, Erik Sørensen, Poul J. Jennum, Kristoffer S. Burgdorf, Brendan Burchell, Adam S. Butterworth, Nicole Soranzo, David B. Rye, Lynn Marie Trotti, Prabhjyot Saini, Lilja Stefansdottir, Sigurdur H. Magnusson, Gudmar Thorleifsson, Thordur Sigmundsson, Albert P. Sigurdsson, Katja Van Den Hurk, Franke Quee, Michael W. T. Tanck, Willem H. Ouwehand, David J. Roberts, Eric J. Earley, Michael P. Busch, Alan E. Mast, Grier P. Page, John Danesh, Emanuele Di Angelantonio, Hreinn Stefansson, Henrik Ullum, Kari Stefansson
Publicado 2020

3D test sample for the calibration and quality control of stimulated emission depletion (STED) and confocal microscopes

por Ernest B. van der Wee, Jantina Fokkema, Chris L. Kennedy, Marc del Pozo, D. A. Matthijs de Winter, Peter N. A. Speets, Hans C. Gerritsen, Alfons van Blaaderen
Publicado 2021

Development of a mechanistic model to predict synthetic biotic activity in healthy volunteers and patients with phenylketonuria

por Mark R. Charbonneau, William S. Denney, Nicholas G. Horvath, Pasquale Cantarella, Mary J. Castillo, Marja K. Puurunen, Aoife M. Brennan
Publicado 2021

Substrate-binding destabilizes the hydrophobic cluster to relieve the autoinhibition of bacterial ubiquitin ligase IpaH9.8

por Yuxin Ye, Yuxian Xiong, Hao Huang
Publicado 2020

Dynamin-related protein 1 deficiency accelerates lipopolysaccharide-induced acute liver injury and inflammation in mice

por Lixiang Wang, Xin Li, Yuki Hanada, Nao Hasuzawa, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto
Publicado 2021

“Be kind to yourself”: an interview with Sebastian Groh on being a transgender early career scientist during a global pandemic

Publicado 2021

Extracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections

por Junlan Liu, Zhen Shen, Jin Tang, Qian Huang, Ying Jian, Yao Liu, Yanan Wang, Xiaowei Ma, Qian Liu, Lei He, Min Li
Publicado 2021

Common variants in SOX-2 and congenital cataract genes contribute to age-related nuclear cataract

por Ekaterina Yonova-Doing, Wanting Zhao, Robert P. Igo, Chaolong Wang, Periasamy Sundaresan, Kristine E. Lee, Gyungah R. Jun, Alexessander Couto Alves, Xiaoran Chai, Anita S. Y. Chan, Mei Chin Lee, Allan Fong, Ava G. Tan, Chiea Chuen Khor, Emily Y. Chew, Pirro G. Hysi, Qiao Fan, Jacqueline Chua, Jaeyoon Chung, Jiemin Liao, Johanna M. Colijn, Kathryn P. Burdon, Lars G. Fritsche, Maria K. Swift, Maryam H. Hilmy, Miao Ling Chee, Milly Tedja, Pieter W. M. Bonnemaijer, Preeti Gupta, Queenie S. Tan, Zheng Li, Eranga N. Vithana, Ravilla D. Ravindran, Soon-Phaik Chee, Yuan Shi, Wenting Liu, Xinyi Su, Xueling Sim, Yang Shen, Ya Xing Wang, Hengtong Li, Yih-Chung Tham, Yik Ying Teo, Tin Aung, Kerrin S. Small, Paul Mitchell, Jost B. Jonas, Tien Yin Wong, Astrid E. Fletcher, Caroline C. W. Klaver, Barbara E. K. Klein, Jie Jin Wang, Sudha K. Iyengar, Christopher J. Hammond, Ching-Yu Cheng
Publicado 2020

A general mechanism of KCNE1 modulation of KCNQ1 channels involving non-canonical VSD-PD coupling

por Xiaoan Wu, Marta E. Perez, Sergei Yu Noskov, H. Peter Larsson
Publicado 2021

Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum

por Elizabeth S. Egan, Michael P. Weekes, Usheer Kanjee, Jale Manzo, Ashwin Srinivasan, Christine Lomas-Francis, Connie Westhoff, Junko Takahashi, Mitsunobu Tanaka, Seishi Watanabe, Carlo Brugnara, Steven P. Gygi, Yoshihiko Tani, Manoj T. Duraisingh
Publicado 2018

Archaeopteryx feather sheaths reveal sequential center-out flight-related molting strategy

por Thomas G. Kaye, Michael Pittman, William R. Wahl
Publicado 2020

Single-trial modeling separates multiple overlapping prediction errors during reward processing in human EEG

por Colin W. Hoy, Sheila C. Steiner, Robert T. Knight
Publicado 2021

The kinetics of humoral response and its relationship with the disease severity in COVID-19

por Lili Ren, Lulu Zhang, De Chang, Junwen Wang, Yongfeng Hu, Hong Chen, Li Guo, Chao Wu, Conghui Wang, Yingying Wang, Ying Wang, Geng Wang, Siyuan Yang, Charles S. Dela Cruz, Lokesh Sharma, Linghang Wang, Dingyu Zhang, Jianwei Wang
Publicado 2020

Inhibition of lung tumorigenesis by a small molecule CA170 targeting the immune checkpoint protein VISTA

por Jing Pan, Yao Chen, Qi Zhang, Achia Khatun, Katie Palen, Gang Xin, Li Wang, Chuanjia Yang, Bryon D. Johnson, Charles R. Myers, Shizuko Sei, Robert H. Shoemaker, Ronald A. Lubet, Yian Wang, Weiguo Cui, Ming You
Publicado 2021

Nasopharyngeal carcinoma MHC region deep sequencing identifies HLA and novel non-HLA TRIM31 and TRIM39 loci

por Lvwen Ning, Josephine Mun-Yee Ko, Valen Zhuoyou Yu, Hoi Yan Ng, Candy King-Chi Chan, Lihua Tao, Shiu-Yeung Lam, Merrin Man-Long Leong, Roger Kai-Cheong Ngan, Dora Lai-Wan Kwong, Anne Wing-Mui Lee, Wai-Tong Ng, Ashley Cheng, Stewart Tung, Victor Ho-Fun Lee, Ka-On Lam, Chung-Kong Kwan, Wing-Sum Li, Stephen Yau, Jin-Xin Bei, Maria Li Lung
Publicado 2020

Diversity of neurovascular coupling dynamics along vascular arbors in layer II/III somatosensory cortex

por Ravi L. Rungta, Marc Zuend, Ali-Kemal Aydin, Éric Martineau, Davide Boido, Bruno Weber, Serge Charpak
Publicado 2021

An in situ activity assay for lysyl oxidases

por Huilei Wang, Alan Poe, Lydia Pak, Kavitha Nandakumar, Sandeep Jandu, Jochen Steppan, Reik Löser, Lakshmi Santhanam
Publicado 2021

Human blood microRNA hsa-miR-21-5p induces vitellogenin in the mosquito Aedes aegypti

por Hugo D. Perdomo, Mazhar Hussain, Rhys Parry, Kayvan Etebari, Lauren M. Hedges, Guangmei Zhang, Benjamin L. Schulz, Sassan Asgari
Publicado 2021