KRAS(G12C)–AMG 510 interaction dynamics revealed by all-atom molecular dynamics simulations

por Tatu Pantsar
Publicado 2020

Surface Kondo effect and non-trivial metallic state of the Kondo insulator YbB12

por Kenta Hagiwara, Yoshiyuki Ohtsubo, Masaharu Matsunami, Shin-ichiro Ideta, Kiyohisa Tanaka, Hidetoshi Miyazaki, Julien E. Rault, Patrick Le Fèvre, François Bertran, Amina Taleb-Ibrahimi, Ryu Yukawa, Masaki Kobayashi, Koji Horiba, Hiroshi Kumigashira, Kazuki Sumida, Taichi Okuda, Fumitoshi Iga, Shin-ichi Kimura
Publicado 2016

Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment

por Tyler K. Ulland, Nidhi Jain, Emma E. Hornick, Eric I. Elliott, Gwendolyn M. Clay, Jeffrey J. Sadler, Kathleen A. M. Mills, Ann M. Janowski, A. Paige Davis Volk, Kai Wang, Kevin L. Legge, Lokesh Gakhar, Mohammed Bourdi, Polly J. Ferguson, Mary E. Wilson, Suzanne L. Cassel, Fayyaz S. Sutterwala
Publicado 2016

Heatstroke predictions by machine learning, weather information, and an all-population registry for 12-hour heatstroke alerts

por Soshiro Ogata, Misa Takegami, Taira Ozaki, Takahiro Nakashima, Daisuke Onozuka, Shunsuke Murata, Yuriko Nakaoku, Koyu Suzuki, Akihito Hagihara, Teruo Noguchi, Koji Iihara, Keiichi Kitazume, Tohru Morioka, Shin Yamazaki, Takahiro Yoshida, Yoshiki Yamagata, Kunihiro Nishimura
Publicado 2021

Allele-specific RT-PCR for the rapid detection of recurrent SLC12A3 mutations for Gitelman syndrome

por Ming-Tso Yan, Sung-Sen Yang, Min-Hua Tseng, Chih-Jen Cheng, Jeng-Daw Tsai, Chih-Chien Sung, Yu-Juei Hsu, Shih-Hua Lin
Publicado 2021

Author Correction: AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines

por Liyang Zhang, John A. Zuris, Ramya Viswanathan, Jasmine N. Edelstein, Rolf Turk, Bernice Thommandru, H. Tomas Rube, Steve E. Glenn, Michael A. Collingwood, Nicole M. Bode, Sarah F. Beaudoin, Swarali Lele, Sean N. Scott, Kevin M. Wasko, Steven Sexton, Christopher M. Borges, Mollie S. Schubert, Gavin L. Kurgan, Matthew S. McNeill, Cecilia A. Fernandez, Vic E. Myer, Richard A. Morgan, Mark A. Behlke, Christopher A. Vakulskas
Publicado 2021

Development of thymic tumor in [LSL:Kras G12D ; Pdx1-CRE] mice, an adverse effect associated with accelerated pancreatic carcinogenesis

por Sophie Liot, Naïma El Kholti, Jonathan Balas, Laurent Genestier, Bernard Verrier, Ulrich Valcourt, Elise Lambert
Publicado 2021

Generation of KS-58 as the first K-Ras(G12D)-inhibitory peptide presenting anti-cancer activity in vivo

por Kotaro Sakamoto, Teruaki Masutani, Takatsugu Hirokawa
Publicado 2020

Large scale cytokine profiling uncovers elevated IL12-p70 and IL-17A in severe pediatric acute respiratory distress syndrome

por Judith Ju Ming Wong, Herng Lee Tan, Jieliang Zhou, Jan Hau Lee, Jing Yao Leong, Joo Guan Yeo, Yie Hou Lee
Publicado 2021

Structure of the hyperosmolality-gated calcium-permeable channel OSCA1.2

por Xin Liu, Jiawei Wang, Linfeng Sun
Publicado 2018

Genome-wide high-throughput screening of interactive bacterial metabolite in the algal population using Escherichia coli K-12 Keio collection

por Jina Heo, Kichul Cho, Urim Kim, Dae-Hyun Cho, Sora Ko, Quynh-Giao Tran, Yong Jae Lee, Choong-Min Ryu, Hee-Sik Kim
Publicado 2020

Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity

por S. W. Fanning, L. Hodges-Gallagher, D. C. Myles, R. Sun, C. E. Fowler, I. N. Plant, B. D. Green, C. L. Harmon, G. L. Greene, P. J. Kushner
Publicado 2018

Progression of prostate carcinoma is promoted by adipose stromal cell-secreted CXCL12 signaling in prostate epithelium

por Fei Su, Alexes C. Daquinag, Songyeon Ahn, Achinto Saha, Yulin Dai, Zhongming Zhao, John DiGiovanni, Mikhail G. Kolonin
Publicado 2021

Structural, microstructural, magnetic and electromagnetic absorption properties of spiraled multiwalled carbon nanotubes/barium hexaferrite (MWCNTs/BaFe12O19) hybrid

por Nurshahiera Rosdi, Raba’ah Syahidah Azis, Ismayadi Ismail, Nurhidayaty Mokhtar, Muhammad Misbah Muhammad Zulkimi, Muhammad Syazwan Mustaffa
Publicado 2021

Insights into the structures and electronic properties of Cun+1 μ and CunS μ (n = 1–12; μ = 0, ±1) clusters

por Cheng-Gang Li, Zi-Gang Shen, Yan-Fei Hu, Ya-Nan Tang, Wei-Guang Chen, Bao-Zeng Ren
Publicado 2017

miR-12 and miR-124 contribute to defined early phases of long-lasting and transient memory

por Julia Michely, Susanne Kraft, Uli Müller
Publicado 2017

Vitamin B12 as a carrier of peptide nucleic acid (PNA) into bacterial cells

por Marcin Równicki, Monika Wojciechowska, Aleksandra J. Wierzba, Jakub Czarnecki, Dariusz Bartosik, Dorota Gryko, Joanna Trylska
Publicado 2017

Identification of the functional variant driving ORMDL3 and GSDMB expression in human chromosome 17q12-21 in primary biliary cholangitis

por Yuki Hitomi, Kaname Kojima, Minae Kawashima, Yosuke Kawai, Nao Nishida, Yoshihiro Aiba, Michio Yasunami, Masao Nagasaki, Minoru Nakamura, Katsushi Tokunaga
Publicado 2017

Particle size-related limitations of persistent phosphors based on the doped Y3Al2Ga3O12 system

por Vitalii Boiko, Zhengfa Dai, Marta Markowska, Cristina Leonelli, Cecilia Mortalò, Francesco Armetta, Federica Ursi, Giorgio Nasillo, Maria Luisa Saladino, Dariusz Hreniak
Publicado 2021

Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity

por Divya Sagar, Narendra P. Singh, Rashida Ginwala, Xiaofang Huang, Ramila Philip, Mitzi Nagarkatti, Prakash Nagarkatti, Konstantin Neumann, Jürgen Ruland, Allison M. Andrews, Servio H. Ramirez, Zafar K. Khan, Pooja Jain
Publicado 2017