An alkaloid initiates phosphodiesterase 3A–schlafen 12 dependent apoptosis without affecting the phosphodiesterase activity

por Youwei Ai, Haibing He, Peihao Chen, Bo Yan, Wenbin Zhang, Zhangcheng Ding, Dianrong Li, Jie Chen, Yan Ma, Yang Cao, Jie Zhu, Jiaojiao Li, Jinjie Ou, Shan Du, Xiaodong Wang, Jianzhang Ma, Shuanhu Gao, Xiangbing Qi
Publicado 2020

Fabrication of Li4Ti5O12-TiO2 Nanosheets with Structural Defects as High-Rate and Long-Life Anodes for Lithium-Ion Batteries

por Hui Xu, Jian Chen, Yanhuai Li, Xinli Guo, Yuanfang Shen, Dan Wang, Yao Zhang, Zengmei Wang
Publicado 2017

Extracellular redox sensitivity of Kv1.2 potassium channels

por Victoria A. Baronas, Runying Y. Yang, Harley T. Kurata
Publicado 2017

Pediatric vision screening using the plusoptiX A12C photoscreener in Chinese preschool children aged 3 to 4 years

por Dan Huang, Xuejuan Chen, Xiaohan Zhang, Yue Wang, Hui Zhu, Hui Ding, Jing Bai, Ji Chen, Zhujun Fu, Zijin Wang, Hu Liu
Publicado 2017

12-Hydroxyeicosapentaenoic acid inhibits foam cell formation and ameliorates high-fat diet-induced pathology of atherosclerosis in mice

por Takahiro Nagatake, Yuki Shibata, Sakiko Morimoto, Eri Node, Kento Sawane, So-ichiro Hirata, Jun Adachi, Yuichi Abe, Junko Isoyama, Azusa Saika, Koji Hosomi, Takeshi Tomonaga, Jun Kunisawa
Publicado 2021

Evaluation of a Recombinant Newcastle Disease Virus Expressing Human IL12 against Human Breast Cancer

por Zahiah Mohamed Amin, Muhamad Alhapis Che Ani, Sheau Wei Tan, Swee Keong Yeap, Noorjahan Banu Alitheen, Syed Umar Faruq Syed Najmuddin, Jeevanathan Kalyanasundram, Soon Choy Chan, Abhi Veerakumarasivam, Suet Lin Chia, Khatijah Yusoff
Publicado 2019

SlMYB12 Regulates Flavonol Synthesis in Three Different Cherry Tomato Varieties

por Shaoli Wang, Zhaohui Chu, Ru Jia, Fei Dan, Xiangling Shen, Yang Li, Xinhua Ding
Publicado 2018

Variation in Raw Milk Microbiota Throughout 12 Months and the Impact of Weather Conditions

por Nan Li, Yuezhu Wang, Chunping You, Jing Ren, Wanyi Chen, Huajun Zheng, Zhenmin Liu
Publicado 2018

Tumour-targeted interleukin-12 and entinostat combination therapy improves cancer survival by reprogramming the tumour immune cell landscape

por Kristin C. Hicks, Paul L. Chariou, Yohei Ozawa, Christine M. Minnar, Karin M. Knudson, Thomas J. Meyer, Jing Bian, Margaret Cam, Jeffrey Schlom, Sofia R. Gameiro
Publicado 2021

Contribution of SLC22A12 on hypouricemia and its clinical significance for screening purposes

por Do Hyeon Cha, Heon Yung Gee, Raul Cachau, Jong Mun Choi, Daeui Park, Sun Ha Jee, Seungho Ryu, Kyeong Kyu Kim, Hong-Hee Won, Sophie Limou, Woojae Myung, Cheryl A. Winkler, Sung Kweon Cho
Publicado 2019

Disruption of Cav1.2-mediated signaling is a pathway for ketamine-induced pathology

por Huan Chen, David H. Vandorpe, Xiang Xie, Seth L. Alper, Mark L. Zeidel, Weiqun Yu
Publicado 2020

Differential Expression Profile of NLRs and AIM2 in Glioma and Implications for NLRP12 in Glioblastoma

por Nidhi Sharma, Shivanjali Saxena, Ishan Agrawal, Shalini Singh, Varsha Srinivasan, S. Arvind, Sridhar Epari, Sushmita Paul, Sushmita Jha
Publicado 2019

Mesenchymal stromal cells as carriers of IL-12 reduce primary and metastatic tumors of murine melanoma

por Natalia Kułach, Ewelina Pilny, Tomasz Cichoń, Justyna Czapla, Magdalena Jarosz-Biej, Marek Rusin, Alina Drzyzga, Sybilla Matuszczak, Stanisław Szala, Ryszard Smolarczyk
Publicado 2021

Aldosterone Impairs Mitochondrial Function in Human Cardiac Fibroblasts via A-Kinase Anchor Protein 12

por Jaime Ibarrola, Rafael Sadaba, Ernesto Martinez-Martinez, Amaia Garcia-Peña, Vanessa Arrieta, Virginia Alvarez, Amaya Fernández-Celis, Alicia Gainza, Victoria Cachofeiro, Enrique Santamaria, Joaquin Fernandez-Irigoyen, Frederic Jaisser, Natalia Lopez-Andres
Publicado 2018

Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target

por Revathi Raman, Weam Fallatah, Ayah Al Qaryoute, Sanchi Dhinoja, Pudur Jagadeeswaran
Publicado 2021

A new look at risk patterns related to coronary heart disease incidence using survival tree analysis: 12 Years Longitudinal Study

por Azra Ramezankhani, Farideh Bagherzadeh-Khiabani, Davood Khalili, Fereidoun Azizi, Farzad Hadaegh
Publicado 2017

An alternative conformation of ERβ bound to estradiol reveals H12 in a stable antagonist position

por Paulo C. T. Souza, Larissa C. Textor, Denise C. Melo, Alessandro S. Nascimento, Munir S. Skaf, Igor Polikarpov
Publicado 2017

Pyrocurrent anomalies and intrinsic magnetodielectric behavior near room temperature in Li2Ni2Mo3O12, a compound with distorted honeycomb and spin-chains

por Sanjay Kumar Upadhyay, Kartik K. Iyer, Smita Gohil, Shankar Ghosh, P. L. Paulose, E. V. Sampathkumaran
Publicado 2017

Inflammatory monocytes regulate Th1 oriented immunity to CpG adjuvanted protein vaccines through production of IL-12

por S. De Koker, L. Van Hoecke, A. De Beuckelaer, K. Roose, K. Deswarte, M. A. Willart, P. Bogaert, T. Naessens, B. G. De Geest, X. Saelens, B. N. Lambrecht, J. Grooten
Publicado 2017

Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase

por Colin W. Garvie, Xiaoyun Wu, Malvina Papanastasiou, Sooncheol Lee, James Fuller, Gavin R. Schnitzler, Steven W. Horner, Andrew Baker, Terry Zhang, James P. Mullahoo, Lindsay Westlake, Stephanie H. Hoyt, Marcus Toetzl, Matthew J. Ranaghan, Luc de Waal, Joseph McGaunn, Bethany Kaplan, Federica Piccioni, Xiaoping Yang, Martin Lange, Adrian Tersteegen, Donald Raymond, Timothy A. Lewis, Steven A. Carr, Andrew D. Cherniack, Christopher T. Lemke, Matthew Meyerson, Heidi Greulich
Publicado 2021