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  1. 12681
    CRISPR-Cas9-based mutagenesis frequently provokes on-target mRNA misregulation
    “...CRISPR-Cas9 genome editing is presumed to knock out gene function by generating a frameshift during...”
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  2. 12682
    Spatial rearrangement of the Streptomyces venezuelae linear chromosome during sporogenic development
    “... of multi-genomic hyphae that differentiate into mono-genomic exospores. Here, Szafran et al. show...”
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  3. 12683
    Uncovering de novo gene birth in yeast using deep transcriptomics
    “...Genome-wide studies of de novo genes have tended to focus on genomic open reading frames (ORFs...”
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  4. 12684
    DNA transposon activity is associated with increased mutation rates in genes of rice and other grasses
    “...DNA transposons are numerous in plant genomes. Here, Wicker et al. analyse transposon polymorphisms...”
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  5. 12685
    Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank
    “...Kim Valette et al. perform a genomic study on asthma integrating genome-wide association study...”
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  6. 12686
    Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts
    “...Pleiotropic loci and genome-wide genetic correlations have identified shared heritability across...”
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  7. 12687
    Temporal Stability and Genetic Diversity of 48-Year-Old T-Series Phages
    por Dinesh Subedi, Jeremy J. Barr
    Publicado 2021
    “... the T-even phages produced viable virions. We obtained complete genomes of these T-even phages, along...”
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  8. 12688
    Resources and costs for microbial sequence analysis evaluated using virtual machines and cloud computing.
    “...<h4>Background</h4>The widespread popularity of genomic applications is threatened...”
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  9. 12689
    Leave no stone unturned: individually adapted xerotolerant Thaumarchaeota sheltered below the boulders of the Atacama Desert hyperarid core
    “... across three distantly located boulder accumulations in the Atacama Desert hyperarid core. Results Genome...”
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  10. 12690
    Evolution of Divergent Life History Strategies in Marine Alphaproteobacteria
    “... model to understand how genome content supporting different life history strategies evolved...”
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  11. 12691
    Lifestyle Evolution in Cyanobacterial Symbionts of Sponges
    “... of marine sponges. The first draft genome of a “Ca. Synechococcus spongiarum” group member was recently...”
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  12. 12692
    Hidden diversity of soil giant viruses
    “... and identify 16 novel giant virus genomes, some of which representing novel lineages, including the so far...”
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  13. 12693
    Parental relatedness through time revealed by runs of homozygosity in ancient DNA
    “... of homozygosity (ROH) in the offspring’s genome can give clues. Here, the authors present a method to identify ROH...”
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  14. 12694
    Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals
    “...Identifying causal variants and genes in genome-wide association studies remains a challenge...”
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  15. 12695
    A dsRNA virus with filamentous viral particles
    “...Viruses with double-stranded RNA (dsRNA) genomes form typically isometric particles or are capsid...”
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  16. 12696
    Dynamics of replication origin over-activation
    “... patterns in cancer cells undergoing partial genome re-replication to reveal that re-replication exhibits...”
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  17. 12697
    Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure
    “...Viral capsids need to protect the genome against harsh environmental conditions and cope with high...”
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  18. 12698
    Sociality sculpts similar patterns of molecular evolution in two independently evolved lineages of eusocial bees
    “...Shell et al. compare the molecular evolution of bee genomes across species with varying social...”
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  19. 12699
    Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes
    “...More than 100 risk loci for schizophrenia have been identified by genome-wide association studies...”
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  20. 12700
    Fine scale human genetic structure in three regions of Cameroon reveals episodic diversifying selection
    “... with Cameroonian ethnicities in malaria genome-wide association studies in sub-Saharan Africa. Genotype data...”
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