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13261por Soulafa Mamlouk, Liam Harold Childs, Daniela Aust, Daniel Heim, Friederike Melching, Cristiano Oliveira, Thomas Wolf, Pawel Durek, Dirk Schumacher, Hendrik Bläker, Moritz von Winterfeld, Bastian Gastl, Kerstin Möhr, Andrea Menne, Silke Zeugner, Torben Redmer, Dido Lenze, Sascha Tierling, Markus Möbs, Wilko Weichert, Gunnar Folprecht, Eric Blanc, Dieter Beule, Reinhold Schäfer, Markus Morkel, Frederick Klauschen, Ulf Leser, Christine Sers“... to therapy. Here, the authors use genomic analyses to study heterogeneity in colorectal cancer and perform...”
Publicado 2017
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13262por Emily Yun-Chia Chang, Shuhe Tsai, Maria J. Aristizabal, James P. Wells, Yan Coulombe, Franciele F. Busatto, Yujia A. Chan, Arun Kumar, Yi Dan Zhu, Alan Ying-Hsu Wang, Louis-Alexandre Fournier, Philip Hieter, Michael S. Kobor, Jean-Yves Masson, Peter C. Stirling“...Accumulations of R-loops can lead to genome instability. Here the authors reveal a role for the MRN...”
Publicado 2019
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13263por Yuchen Zhang, Chang Jiang, Stephen J. Trudeau, Yohei Narita, Bo Zhao, Mingxiang Teng, Rui Guo, Benjamin E. Gewurz“... epigenetic factors necessary for EBV latency, we recently performed a human genome-wide CRISPR screen...”
Publicado 2020
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13264por Xin Luo, Yaoxi He, Chao Zhang, Xiechao He, Lanzhen Yan, Min Li, Ting Hu, Yan Hu, Jin Jiang, Xiaoyu Meng, Weizhi Ji, Xudong Zhao, Ping Zheng, Shuhua Xu, Bing Su“... are complex. Here the authors perform whole genome trio sequencing of rhesus monkeys and see no unexpected...”
Publicado 2019
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13265por Beau R. Webber, Cara-lin Lonetree, Mitchell G. Kluesner, Matthew J. Johnson, Emily J. Pomeroy, Miechaleen D. Diers, Walker S. Lahr, Garrett M. Draper, Nicholas J. Slipek, Branden A. Smeester, Klaus N. Lovendahl, Amber N. McElroy, Wendy R. Gordon, Mark J. Osborn, Branden S. Moriarity“...Multiplexed genome engineering with Cas9 can increase efficiency but also the risk of unintended...”
Publicado 2019
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13266por Tae-Min Kim, In Seok Yang, Byung-Joon Seung, Sejoon Lee, Dohyun Kim, Yoo-Jin Ha, Mi-kyoung Seo, Ka-Kyung Kim, Hyun Seok Kim, Jae-Ho Cheong, Jung-Hyang Sur, Hojung Nam, Sangwoo Kim“... avenues. Here, genomic analyses of these tumors highlights a convergence on PI3K-Akt oncogenic pathways....”
Publicado 2020
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13267por Nicola P. Montaldo, Diana L. Bordin, Alessandro Brambilla, Marcel Rösinger, Sarah L. Fordyce Martin, Karine Øian Bjørås, Stefano Bradamante, Per Arne Aas, Antonia Furrer, Lene C. Olsen, Nicolas Kunath, Marit Otterlei, Pål Sætrom, Magnar Bjørås, Leona D. Samson, Barbara van Loon“...How genome stability is maintained at regions of active transcription is currently not entirely...”
Publicado 2019
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13268The genetic landscape of benign thyroid nodules revealed by whole exome and transcriptome sequencingpor Lei Ye, Xiaoyi Zhou, Fengjiao Huang, Weixi Wang, Yicheng Qi, Heng Xu, Yang Shu, Liyun Shen, Xiaochun Fei, Jing Xie, Min Cao, Yulin Zhou, Wei Zhu, Shu Wang, Guang Ning, Weiqing Wang“..., the authors provide genomic evidence that papillary thyroid carcinomas and coincidental benign thyroid nodules...”
Publicado 2017
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13269por M. Charpentier, A. H. Y. Khedher, S. Menoret, A. Brion, K. Lamribet, E. Dardillac, C. Boix, L. Perrouault, L. Tesson, S. Geny, A. De Cian, J. M. Itier, I. Anegon, B. Lopez, C. Giovannangeli, J. P. Concordet“...The integration of exogenous DNA into the genome using CRISPR–Cas9 often presents a challenge...”
Publicado 2018
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13270“...). After the non-polymerase chain reaction (PCR), amplified Bt genomic DNA were fluorescent-labeled using a...”
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13271por Wang,Qin, Wang,Yingli, Yang,Zhen, He,Shaoguo, Wu,Qiang, Li,Jifen, Li,Zhengwen, Zhou,Yan“..., the complete genome sequences of six CYVCV isolates from different hosts were sequenced. Comparisons...”
Publicado 2020
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13272por Frederik Helmprobst, Susanne Kneitz, Barbara Klotz, Magali Naville, Corentin Dechaud, Jean-Nicolas Volff, Manfred Schartl“... of metastasis and increased genomic instability leading to a high mutation rate and the development...”
Publicado 2021
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13273por Nicolas Waespe, Santhosh Dhanraj, Manju Wahala, Elena Tsangaris, Tom Enbar, Bozana Zlateska, Hongbing Li, Robert J. Klaassen, Conrad V. Fernandez, Geoff D. E. Cuvelier, John K. Wu, Yves D. Pastore, Mariana Silva, Jeffrey H. Lipton, Joseé Brossard, Bruno Michon, Sharon Abish, MacGregor Steele, Roona Sinha, Mark J. Belletrutti, Vicky R. Breakey, Lawrence Jardine, Lisa Goodyear, Liat Kofler, Michaela Cada, Lillian Sung, Mary Shago, Stephen W. Scherer, Yigal Dror“...Blood disorders: impact of genomic structural variation Copy number variation in patients...”
Publicado 2017
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13274“... of retroviruses by protecting and transporting the viral genome towards the nucleus of the infected cell until its...”
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13275por Ryan Z Friedman, David M Granas, Connie A Myers, Joseph C Corbo, Barak A Cohen, Michael A White“... in genomic assays of TF binding or chromatin state. To identify sequence features that distinguish enhancers...”
Publicado 2021
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13276por Jarosław Bryk, Emilie Hardouin, Irina Pugach, David Hughes, Rainer Strotmann, Mark Stoneking, Sean Myles“...Genome-wide scans for positive selection in humans provide a promising approach to establish links...”
Publicado 2008
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13277por EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Boet Glandorf, Lieve Herman, Jaime Aguilera, Yi Liu, Andrew Chesson“... to uncertainties about the presence of a gene conferring resistance to antimicrobials in the genome...”
Publicado 2021
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13278“... by resistance to induction of apoptosis, aberrant increased proliferation and genomic instability. Specific...”
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13279“...Nucleotypic theory suggests that genome size play indirect roles in determining organismal fitness...”
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13280por Frederik Helmprobst, Susanne Kneitz, Barbara Klotz, Magali Naville, Corentin Dechaud, Jean-Nicolas Volff, Manfred Schartl“... of metastasis and increased genomic instability leading to a high mutation rate and the development...”
Publicado 2021
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