Fluvastatin mitigates SARS-CoV-2 infection in human lung cells

por Francisco J. Zapatero-Belinchón, Rebecca Moeller, Lisa Lasswitz, Marco van Ham, Miriam Becker, Graham Brogden, Ebba Rosendal, Wenjie Bi, Belén Carriquí-Madroñal, Koushikul Islam, Annasara Lenman, Antonia P. Gunesch, Jared Kirui, Thomas Pietschmann, Anna K. Överby, Lothar Jänsch, Gisa Gerold
Publicado 2021

Repurposing potential of posaconazole and grazoprevir as inhibitors of SARS-CoV-2 helicase

por Syed Hani Abidi, Nahlah Makki Almansour, Daulet Amerzhanov, Khaled S. Allemailem, Wardah Rafaqat, Mahmoud A. A. Ibrahim, Philip la Fleur, Martin Lukac, Syed Ali
Publicado 2021

Complementary methods for SARS-CoV-2 diagnosis in times of material shortage

por Thaisa Lucas Sandri, Juliana Inoue, Johanna Geiger, Johanna-Marie Griesbaum, Constanze Heinzel, Michael Burnet, Rolf Fendel, Peter G. Kremsner, Jana Held, Andrea Kreidenweiss
Publicado 2021

Rapid and sensitive detection of SARS-CoV-2 antibodies by biolayer interferometry

por John V. Dzimianski, Nicholas Lorig-Roach, Sara M. O’Rourke, David L. Alexander, Jacqueline M. Kimmey, Rebecca M. DuBois
Publicado 2020

In vitro efficacy of artemisinin-based treatments against SARS-CoV-2

por Yuyong Zhou, Kerry Gilmore, Santseharay Ramirez, Eva Settels, Karen A. Gammeltoft, Long V. Pham, Ulrik Fahnøe, Shan Feng, Anna Offersgaard, Jakob Trimpert, Jens Bukh, Klaus Osterrieder, Judith M. Gottwein, Peter H. Seeberger
Publicado 2021

Immunoinformatics mapping of potential epitopes in SARS-CoV-2 structural proteins

por Yengkhom Damayanti Devi, Himanshu Ballav Goswami, Sushmita Konwar, Chandrima Doley, Anutee Dolley, Arpita Devi, Chen Chongtham, Dikshita Dowerah, Vashkar Biswa, Latonglila Jamir, Aditya Kumar, Siddhartha Shankar Satapathy, Suvendra Kumar Ray, Ramesh Chandra Deka, Robin Doley, Manabendra Mandal, Sandeep Das, Chongtham Shyamsunder Singh, Partha Pratim Borah, Pabitra Nath, Nima D. Namsa
Publicado 2021

Gamma-irradiated SARS-CoV-2 vaccine candidate, OZG-38.61.3, confers protection from SARS-CoV-2 challenge in human ACEII-transgenic mice

por Raife Dilek Turan, Cihan Tastan, Derya Dilek Kancagi, Bulut Yurtsever, Gozde Sir Karakus, Samed Ozer, Selen Abanuz, Didem Cakirsoy, Gamze Tumentemur, Sevda Demir, Utku Seyis, Recai Kuzay, Muhammer Elek, Miyase Ezgi Kocaoglu, Gurcan Ertop, Serap Arbak, Merve Acikel Elmas, Cansu Hemsinlioglu, Ozden Hatirnaz Ng, Sezer Akyoney, Ilayda Sahin, Cavit Kerem Kayhan, Fatma Tokat, Gurler Akpinar, Murat Kasap, Ayse Sesin Kocagoz, Ugur Ozbek, Dilek Telci, Fikrettin Sahin, Koray Yalcin, Siret Ratip, Umit Ince, Ercument Ovali
Publicado 2021

Seeds of change: reversing the erosion of traditional agroecological knowledge through a citizen science school program in Catalonia, Spain

por Petra Benyei, Laura Aceituno-Mata, Laura Calvet-Mir, Javier Tardío, Manuel Pardo-de-Santayana, David García-del-Amo, Marta Rivera-Ferre, María Molina-Simón, Airy Gras, Antonio Perdomo-Molina, Sara Guadilla-Sáez, Victoria Reyes-García
Publicado 2020

Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase

por Joseph A. Newman, Alice Douangamath, Setayesh Yadzani, Yuliana Yosaatmadja, Antony Aimon, José Brandão-Neto, Louise Dunnett, Tyler Gorrie-stone, Rachael Skyner, Daren Fearon, Matthieu Schapira, Frank von Delft, Opher Gileadi
Publicado 2021

SARS-CoV-2 infection induces the dedifferentiation of multiciliated cells and impairs mucociliary clearance

por Rémy Robinot, Mathieu Hubert, Guilherme Dias de Melo, Françoise Lazarini, Timothée Bruel, Nikaïa Smith, Sylvain Levallois, Florence Larrous, Julien Fernandes, Stacy Gellenoncourt, Stéphane Rigaud, Olivier Gorgette, Catherine Thouvenot, Céline Trébeau, Adeline Mallet, Guillaume Duménil, Samy Gobaa, Raphaël Etournay, Pierre-Marie Lledo, Marc Lecuit, Hervé Bourhy, Darragh Duffy, Vincent Michel, Olivier Schwartz, Lisa A. Chakrabarti
Publicado 2021

Molecular evidence of SARS-CoV-2 in New York before the first pandemic wave

por Matthew M. Hernandez, Ana S. Gonzalez-Reiche, Hala Alshammary, Shelcie Fabre, Zenab Khan, Adriana van De Guchte, Ajay Obla, Ethan Ellis, Mitchell J. Sullivan, Jessica Tan, Bremy Alburquerque, Juan Soto, Ching-Yi Wang, Shwetha Hara Sridhar, Ying-Chih Wang, Melissa Smith, Robert Sebra, Alberto E. Paniz-Mondolfi, Melissa R. Gitman, Michael D. Nowak, Carlos Cordon-Cardo, Marta Luksza, Florian Krammer, Harm van Bakel, Viviana Simon, Emilia Mia Sordillo
Publicado 2021

Immune responses to SARS-CoV-2 in three children of parents with symptomatic COVID-19

por Shidan Tosif, Melanie R. Neeland, Philip Sutton, Paul V. Licciardi, Sohinee Sarkar, Kevin J. Selva, Lien Anh Ha Do, Celeste Donato, Zheng Quan Toh, Rachel Higgins, Carolien Van de Sandt, Melissa M. Lemke, Christina Y. Lee, Suzanne K. Shoffner, Katie L. Flanagan, Kelly B. Arnold, Francesca L. Mordant, Kim Mulholland, Julie Bines, Kate Dohle, Daniel G. Pellicci, Nigel Curtis, Sarah McNab, Andrew Steer, Richard Saffery, Kanta Subbarao, Amy W. Chung, Katherine Kedzierska, David P. Burgner, Nigel W. Crawford
Publicado 2020

Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2

por Yusuke Higuchi, Tatsuya Suzuki, Takao Arimori, Nariko Ikemura, Emiko Mihara, Yuhei Kirita, Eriko Ohgitani, Osam Mazda, Daisuke Motooka, Shota Nakamura, Yusuke Sakai, Yumi Itoh, Fuminori Sugihara, Yoshiharu Matsuura, Satoaki Matoba, Toru Okamoto, Junichi Takagi, Atsushi Hoshino
Publicado 2021

SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals

por Nils C. Gassen, Jan Papies, Thomas Bajaj, Jackson Emanuel, Frederik Dethloff, Robert Lorenz Chua, Jakob Trimpert, Nicolas Heinemann, Christine Niemeyer, Friderike Weege, Katja Hönzke, Tom Aschman, Daniel E. Heinz, Katja Weckmann, Tim Ebert, Andreas Zellner, Martina Lennarz, Emanuel Wyler, Simon Schroeder, Anja Richter, Daniela Niemeyer, Karen Hoffmann, Thomas F. Meyer, Frank L. Heppner, Victor M. Corman, Markus Landthaler, Andreas C. Hocke, Markus Morkel, Nikolaus Osterrieder, Christian Conrad, Roland Eils, Helena Radbruch, Patrick Giavalisco, Christian Drosten, Marcel A. Müller
Publicado 2021

Characterization of humoral and SARS-CoV-2 specific T cell responses in people living with HIV

por Aljawharah Alrubayyi, Ester Gea-Mallorquí, Emma Touizer, Dan Hameiri-Bowen, Jakub Kopycinski, Bethany Charlton, Natasha Fisher-Pearson, Luke Muir, Annachiara Rosa, Chloe Roustan, Christopher Earl, Peter Cherepanov, Pierre Pellegrino, Laura Waters, Fiona Burns, Sabine Kinloch, Tao Dong, Lucy Dorrell, Sarah Rowland-Jones, Laura E. McCoy, Dimitra Peppa
Publicado 2021

SARS-CoV-2 antibody seroprevalence and associated risk factors in an urban district in Cameroon

por Kene Nwosu, Joseph Fokam, Franck Wanda, Lucien Mama, Erol Orel, Nicolas Ray, Jeanine Meke, Armel Tassegning, Desire Takou, Eric Mimbe, Beat Stoll, Josselin Guillebert, Eric Comte, Olivia Keiser, Laura Ciaffi
Publicado 2021

Morphogenesis and cytopathic effect of SARS-CoV-2 infection in human airway epithelial cells

por Na Zhu, Wenling Wang, Zhidong Liu, Chaoyang Liang, Wen Wang, Fei Ye, Baoying Huang, Li Zhao, Huijuan Wang, Weimin Zhou, Yao Deng, Longfei Mao, Chongyu Su, Guangliang Qiang, Taijiao Jiang, Jincun Zhao, Guizhen Wu, Jingdong Song, Wenjie Tan
Publicado 2020

Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation

por Nicholas K. Hurlburt, Emilie Seydoux, Yu-Hsin Wan, Venkata Viswanadh Edara, Andrew B. Stuart, Junli Feng, Mehul S. Suthar, Andrew T. McGuire, Leonidas Stamatatos, Marie Pancera
Publicado 2020

SARS-CoV-2 genomic and subgenomic RNAs in diagnostic samples are not an indicator of active replication

por Soren Alexandersen, Anthony Chamings, Tarka Raj Bhatta
Publicado 2020