A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes

por Tal Noy-Porat, Efi Makdasi, Ron Alcalay, Adva Mechaly, Yinon Levy, Adi Bercovich-Kinori, Ayelet Zauberman, Hadas Tamir, Yfat Yahalom-Ronen, Ma’ayan Israeli, Eyal Epstein, Hagit Achdout, Sharon Melamed, Theodor Chitlaru, Shay Weiss, Eldar Peretz, Osnat Rosen, Nir Paran, Shmuel Yitzhaki, Shmuel C. Shapira, Tomer Israely, Ohad Mazor, Ronit Rosenfeld
Publicado 2020

SARS-CoV-2 specific T cell responses are lower in children and increase with age and time after infection

por Carolyn A. Cohen, Athena P. Y. Li, Asmaa Hachim, David S. C. Hui, Mike Y. W. Kwan, Owen T. Y. Tsang, Susan S. Chiu, Wai Hung Chan, Yat Sun Yau, Niloufar Kavian, Fionn N. L. Ma, Eric H. Y. Lau, Samuel M. S. Cheng, Leo L. M. Poon, Malik Peiris, Sophie A. Valkenburg
Publicado 2021

Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin

por Petra Krafcikova, Jan Silhan, Radim Nencka, Evzen Boura
Publicado 2020

Identification of potent human neutralizing antibodies against SARS-CoV-2 implications for development of therapeutics and prophylactics

por Shaojuan Zhao, Huajun Zhang, Xinglou Yang, Haiwei Zhang, Ying Chen, Yancheng Zhan, Xiaoqing Zhang, Rendi Jiang, Meiqin Liu, Lan Liu, Li Chen, Wei Tang, Cheng Peng, Xiaoxiao Gao, Zhe Zhang, Zhengli Shi, Rui Gong
Publicado 2021

A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry

por Yunkai Zhu, Fei Feng, Gaowei Hu, Yuyan Wang, Yin Yu, Yuanfei Zhu, Wei Xu, Xia Cai, Zhiping Sun, Wendong Han, Rong Ye, Di Qu, Qiang Ding, Xinxin Huang, Hongjun Chen, Wei Xu, Youhua Xie, Qiliang Cai, Zhenghong Yuan, Rong Zhang
Publicado 2021

Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors

por Robert N. Kirchdoerfer, Andrew B. Ward
Publicado 2019

Distinct clinical and immunological profiles of patients with evidence of SARS-CoV-2 infection in sub-Saharan Africa

por Ben Morton, Kayla G. Barnes, Catherine Anscombe, Khuzwayo Jere, Prisca Matambo, Jonathan Mandolo, Raphael Kamng’ona, Comfort Brown, James Nyirenda, Tamara Phiri, Ndaziona P. Banda, Charlotte Van Der Veer, Kwazizira S. Mndolo, Kelvin Mponda, Jamie Rylance, Chimota Phiri, Jane Mallewa, Mulinda Nyirenda, Grace Katha, Paul Kambiya, James Jafali, Henry C. Mwandumba, Stephen B. Gordon, Blantyre COVID-19 Consortium, Jennifer Cornick, Kondwani C. Jambo
Publicado 2021

Point-of-care bulk testing for SARS-CoV-2 by combining hybridization capture with improved colorimetric LAMP

por Lukas Bokelmann, Olaf Nickel, Tomislav Maricic, Svante Pääbo, Matthias Meyer, Stephan Borte, Stephan Riesenberg
Publicado 2021

Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain

por Timothy J. C. Tan, Meng Yuan, Kaylee Kuzelka, Gilberto C. Padron, Jacob R. Beal, Xin Chen, Yiquan Wang, Joel Rivera-Cardona, Xueyong Zhu, Beth M. Stadtmueller, Christopher B. Brooke, Ian A. Wilson, Nicholas C. Wu
Publicado 2021

Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya

por Ifedayo M. O. Adetifa, Sophie Uyoga, John N. Gitonga, Daisy Mugo, Mark Otiende, James Nyagwange, Henry K. Karanja, James Tuju, Perpetual Wanjiku, Rashid Aman, Mercy Mwangangi, Patrick Amoth, Kadondi Kasera, Wangari Ng’ang’a, Charles Rombo, Christine Yegon, Khamisi Kithi, Elizabeth Odhiambo, Thomas Rotich, Irene Orgut, Sammy Kihara, Christian Bottomley, Eunice W. Kagucia, Katherine E. Gallagher, Anthony Etyang, Shirine Voller, Teresa Lambe, Daniel Wright, Edwine Barasa, Benjamin Tsofa, Philip Bejon, Lynette I. Ochola-Oyier, Ambrose Agweyu, J. Anthony G. Scott, George M. Warimwe
Publicado 2021

Author Correction: Evidence for SARS-CoV-2 related coronaviruses circulating in bats and pangolins in Southeast Asia

por Supaporn Wacharapluesadee, Chee Wah Tan, Patarapol Maneeorn, Prateep Duengkae, Feng Zhu, Yutthana Joyjinda, Thongchai Kaewpom, Wan Ni Chia, Weenassarin Ampoot, Beng Lee Lim, Kanthita Worachotsueptrakun, Vivian Chih-Wei Chen, Nutthinee Sirichan, Chanida Ruchisrisarod, Apaporn Rodpan, Kirana Noradechanon, Thanawadee Phaichana, Niran Jantarat, Boonchu Thongnumchaima, Changchun Tu, Gary Crameri, Martha M. Stokes, Thiravat Hemachudha, Lin-Fa Wang
Publicado 2021

A broadly neutralizing humanized ACE2-targeting antibody against SARS-CoV-2 variants

por Yanyun Du, Rui Shi, Ying Zhang, Xiaomin Duan, Li Li, Jing Zhang, Fengze Wang, Ruixue Zhang, Hao Shen, Yue Wang, Zheng Wu, Qianwen Peng, Ting Pan, Wanwei Sun, Weijin Huang, Yue Feng, Hui Feng, Junyu Xiao, Wenjie Tan, Youchun Wang, Chenhui Wang, Jinghua Yan
Publicado 2021

An adenovirus-vectored COVID-19 vaccine confers protection from SARS-COV-2 challenge in rhesus macaques

por Liqiang Feng, Qian Wang, Chao Shan, Chenchen Yang, Ying Feng, Jia Wu, Xiaolin Liu, Yiwu Zhou, Rendi Jiang, Peiyu Hu, Xinglong Liu, Fan Zhang, Pingchao Li, Xuefeng Niu, Yichu Liu, Xuehua Zheng, Jia Luo, Jing Sun, Yingying Gu, Bo Liu, Yongcun Xu, Chufang Li, Weiqi Pan, Jincun Zhao, Changwen Ke, Xinwen Chen, Tao Xu, Nanshan Zhong, Suhua Guan, Zhiming Yuan, Ling Chen
Publicado 2020

Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease

por Haixia Su, Sheng Yao, Wenfeng Zhao, Yumin Zhang, Jia Liu, Qiang Shao, Qingxing Wang, Minjun Li, Hang Xie, Weijuan Shang, Changqiang Ke, Lu Feng, Xiangrui Jiang, Jingshan Shen, Gengfu Xiao, Hualiang Jiang, Leike Zhang, Yang Ye, Yechun Xu
Publicado 2021

Large variation in anti-SARS-CoV-2 antibody prevalence among essential workers in Geneva, Switzerland

por Silvia Stringhini, María-Eugenia Zaballa, Nick Pullen, Carlos de Mestral, Javier Perez-Saez, Roxane Dumont, Attilio Picazio, Francesco Pennacchio, Yaron Dibner, Sabine Yerly, Helene Baysson, Nicolas Vuilleumier, Jean-François Balavoine, Delphine Bachmann, Didier Trono, Didier Pittet, François Chappuis, Omar Kherad, Laurent Kaiser, Andrew S. Azman, SEROCoV-WORK + Study Group, Idris Guessous
Publicado 2021

IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals

por Michal A. Stanczak, David E. Sanin, Petya Apostolova, Gabriele Nerz, Dimitrios Lampaki, Maike Hofmann, Daniel Steinmann, Marvin Krohn-Grimberghe, Robert Thimme, Gerhard Mittler, Cornelius F. Waller, Edward J. Pearce, Erika L. Pearce
Publicado 2021

Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity

por Linh T. Bui, Nichelle I. Winters, Mei-I Chung, Chitra Joseph, Austin J. Gutierrez, Arun C. Habermann, Taylor S. Adams, Jonas C. Schupp, Sergio Poli, Lance M. Peter, Chase J. Taylor, Jessica B. Blackburn, Bradley W. Richmond, Andrew G. Nicholson, Doris Rassl, William A. Wallace, Ivan O. Rosas, R. Gisli Jenkins, Naftali Kaminski, Jonathan A. Kropski, Nicholas E. Banovich, Human Cell Atlas Lung Biological Network
Publicado 2021

Effect of specific non-pharmaceutical intervention policies on SARS-CoV-2 transmission in the counties of the United States

por Bingyi Yang, Angkana T. Huang, Bernardo Garcia-Carreras, William E. Hart, Andrea Staid, Matt D. T. Hitchings, Elizabeth C. Lee, Chanelle J. Howe, Kyra H. Grantz, Amy Wesolowksi, Joseph Chadi Lemaitre, Susan Rattigan, Carlos Moreno, Brooke A. Borgert, Celeste Dale, Nicole Quigley, Andrew Cummings, Alizée McLorg, Kaelene LoMonaco, Sarah Schlossberg, Drew Barron-Kraus, Harrison Shrock, UFCOVID Interventions Team, Justin Lessler, Carl D. Laird, Derek A. T. Cummings
Publicado 2021

Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease

por Lifeng Fu, Fei Ye, Yong Feng, Feng Yu, Qisheng Wang, Yan Wu, Cheng Zhao, Huan Sun, Baoying Huang, Peihua Niu, Hao Song, Yi Shi, Xuebing Li, Wenjie Tan, Jianxun Qi, George Fu Gao
Publicado 2020

Multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity

por Irene A. Abela, Chloé Pasin, Magdalena Schwarzmüller, Selina Epp, Michèle E. Sickmann, Merle M. Schanz, Peter Rusert, Jacqueline Weber, Stefan Schmutz, Annette Audigé, Liridona Maliqi, Annika Hunziker, Maria C. Hesselman, Cyrille R. Niklaus, Jochen Gottschalk, Eméry Schindler, Alexander Wepf, Urs Karrer, Aline Wolfensberger, Silvana K. Rampini, Patrick M. Meyer Sauteur, Christoph Berger, Michael Huber, Jürg Böni, Dominique L. Braun, Maddalena Marconato, Markus G. Manz, Beat M. Frey, Huldrych F. Günthard, Roger D. Kouyos, Alexandra Trkola
Publicado 2021