Revealing fine-scale spatiotemporal differences in SARS-CoV-2 introduction and spread

por Gage K. Moreno, Katarina M. Braun, Kasen K. Riemersma, Michael A. Martin, Peter J. Halfmann, Chelsea M. Crooks, Trent Prall, David Baker, John J. Baczenas, Anna S. Heffron, Mitchell Ramuta, Manjeet Khubbar, Andrea M. Weiler, Molly A. Accola, William M. Rehrauer, Shelby L. O’Connor, Nasia Safdar, Caitlin S. Pepperell, Trivikram Dasu, Sanjib Bhattacharyya, Yoshihiro Kawaoka, Katia Koelle, David H. O’Connor, Thomas C. Friedrich
Publicado 2020

Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing

por Sepideh Sadegh, Julian Matschinske, David B. Blumenthal, Gihanna Galindez, Tim Kacprowski, Markus List, Reza Nasirigerdeh, Mhaned Oubounyt, Andreas Pichlmair, Tim Daniel Rose, Marisol Salgado-Albarrán, Julian Späth, Alexey Stukalov, Nina K. Wenke, Kevin Yuan, Josch K. Pauling, Jan Baumbach
Publicado 2020

Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19

por Adam K. Wheatley, Jennifer A. Juno, Jing J. Wang, Kevin J. Selva, Arnold Reynaldi, Hyon-Xhi Tan, Wen Shi Lee, Kathleen M. Wragg, Hannah G. Kelly, Robyn Esterbauer, Samantha K. Davis, Helen E. Kent, Francesca L. Mordant, Timothy E. Schlub, David L. Gordon, David S. Khoury, Kanta Subbarao, Deborah Cromer, Tom P. Gordon, Amy W. Chung, Miles P. Davenport, Stephen J. Kent
Publicado 2021

Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape

por Zhiqiang Ku, Xuping Xie, Edgar Davidson, Xiaohua Ye, Hang Su, Vineet D. Menachery, Yize Li, Zihao Yuan, Xianwen Zhang, Antonio E. Muruato, Ariadna Grinyo i Escuer, Breanna Tyrell, Kyle Doolan, Benjamin J. Doranz, Daniel Wrapp, Paul F. Bates, Jason S. McLellan, Susan R. Weiss, Ningyan Zhang, Pei-Yong Shi, Zhiqiang An
Publicado 2021

A high-resolution temporal atlas of the SARS-CoV-2 translatome and transcriptome

por Doyeon Kim, Sukjun Kim, Joori Park, Hee Ryung Chang, Jeeyoon Chang, Junhak Ahn, Heedo Park, Junehee Park, Narae Son, Gihyeon Kang, Jeonghun Kim, Kisoon Kim, Man-Seong Park, Yoon Ki Kim, Daehyun Baek
Publicado 2021

Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysis

por Rowena A. Bull, Thiruni N. Adikari, James M. Ferguson, Jillian M. Hammond, Igor Stevanovski, Alicia G. Beukers, Zin Naing, Malinna Yeang, Andrey Verich, Hasindu Gamaarachchi, Ki Wook Kim, Fabio Luciani, Sacha Stelzer-Braid, John-Sebastian Eden, William D. Rawlinson, Sebastiaan J. van Hal, Ira W. Deveson
Publicado 2020

Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors

por Sho Iketani, Farhad Forouhar, Hengrui Liu, Seo Jung Hong, Fang-Yu Lin, Manoj S. Nair, Arie Zask, Yaoxing Huang, Li Xing, Brent R. Stockwell, Alejandro Chavez, David D. Ho
Publicado 2021

Favipiravir antiviral efficacy against SARS-CoV-2 in a hamster model

por Jean-Sélim Driouich, Maxime Cochin, Guillaume Lingas, Grégory Moureau, Franck Touret, Paul-Rémi Petit, Géraldine Piorkowski, Karine Barthélémy, Caroline Laprie, Bruno Coutard, Jérémie Guedj, Xavier de Lamballerie, Caroline Solas, Antoine Nougairède
Publicado 2021

SARS-CoV-2 antibody prevalence in England following the first peak of the pandemic

por Helen Ward, Christina Atchison, Matthew Whitaker, Kylie E. C. Ainslie, Joshua Elliott, Lucy Okell, Rozlyn Redd, Deborah Ashby, Christl A. Donnelly, Wendy Barclay, Ara Darzi, Graham Cooke, Steven Riley, Paul Elliott
Publicado 2021

Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection

por Niyati Desai, Azfar Neyaz, Annamaria Szabolcs, Angela R. Shih, Jonathan H. Chen, Vishal Thapar, Linda T. Nieman, Alexander Solovyov, Arnav Mehta, David J. Lieb, Anupriya S. Kulkarni, Christopher Jaicks, Katherine H. Xu, Michael J. Raabe, Christopher J. Pinto, Dejan Juric, Ivan Chebib, Robert B. Colvin, Arthur Y. Kim, Robert Monroe, Sarah E. Warren, Patrick Danaher, Jason W. Reeves, Jingjing Gong, Erroll H. Rueckert, Benjamin D. Greenbaum, Nir Hacohen, Stephen M. Lagana, Miguel N. Rivera, Lynette M. Sholl, James R. Stone, David T. Ting, Vikram Deshpande
Publicado 2020

A novel SARS-CoV-2 related coronavirus in bats from Cambodia

por Deborah Delaune, Vibol Hul, Erik A. Karlsson, Alexandre Hassanin, Tey Putita Ou, Artem Baidaliuk, Fabiana Gámbaro, Matthieu Prot, Vuong Tan Tu, Sokha Chea, Lucy Keatts, Jonna Mazet, Christine K. Johnson, Philippe Buchy, Philippe Dussart, Tracey Goldstein, Etienne Simon-Lorière, Veasna Duong
Publicado 2021

Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives

por Kangsa Amporndanai, Xiaoli Meng, Weijuan Shang, Zhenmig Jin, Michael Rogers, Yao Zhao, Zihe Rao, Zhi-Jie Liu, Haitao Yang, Leike Zhang, Paul M. O’Neill, S. Samar Hasnain
Publicado 2021

Cryo-EM analysis of the post-fusion structure of the SARS-CoV spike glycoprotein

por Xiaoyi Fan, Duanfang Cao, Lingfei Kong, Xinzheng Zhang
Publicado 2020

SARS-CoV-2 viral load is associated with increased disease severity and mortality

por Jesse Fajnzylber, James Regan, Kendyll Coxen, Heather Corry, Colline Wong, Alexandra Rosenthal, Daniel Worrall, Francoise Giguel, Alicja Piechocka-Trocha, Caroline Atyeo, Stephanie Fischinger, Andrew Chan, Keith T. Flaherty, Kathryn Hall, Michael Dougan, Edward T. Ryan, Elizabeth Gillespie, Rida Chishti, Yijia Li, Nikolaus Jilg, Dusan Hanidziar, Rebecca M. Baron, Lindsey Baden, Athe M. Tsibris, Katrina A. Armstrong, Daniel R. Kuritzkes, Galit Alter, Bruce D. Walker, Xu Yu, Jonathan Z. Li, The Massachusetts Consortium for Pathogen Readiness
Publicado 2020

Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2

por Jon Arizti-Sanz, Catherine A. Freije, Alexandra C. Stanton, Brittany A. Petros, Chloe K. Boehm, Sameed Siddiqui, Bennett M. Shaw, Gordon Adams, Tinna-Solveig F. Kosoko-Thoroddsen, Molly E. Kemball, Jessica N. Uwanibe, Fehintola V. Ajogbasile, Philomena E. Eromon, Robin Gross, Loni Wronka, Katie Caviness, Lisa E. Hensley, Nicholas H. Bergman, Bronwyn L. MacInnis, Christian T. Happi, Jacob E. Lemieux, Pardis C. Sabeti, Cameron Myhrvold
Publicado 2020

Evidence of exposure to SARS-CoV-2 in cats and dogs from households in Italy

por E. I. Patterson, G. Elia, A. Grassi, A. Giordano, C. Desario, M. Medardo, S. L. Smith, E. R. Anderson, T. Prince, G. T. Patterson, E. Lorusso, M. S. Lucente, G. Lanave, S. Lauzi, U. Bonfanti, A. Stranieri, V. Martella, F. Solari Basano, V. R. Barrs, A. D. Radford, U. Agrimi, G. L. Hughes, S. Paltrinieri, N. Decaro
Publicado 2020

SARS-CoV-2 transmission across age groups in France and implications for control

por Cécile Tran Kiem, Paolo Bosetti, Juliette Paireau, Pascal Crépey, Henrik Salje, Noémie Lefrancq, Arnaud Fontanet, Daniel Benamouzig, Pierre-Yves Boëlle, Jean-Claude Desenclos, Lulla Opatowski, Simon Cauchemez
Publicado 2021

The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2

por Ryan D. Chow, Medha Majety, Sidi Chen
Publicado 2021

The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA

por Jasmine Cubuk, Jhullian J. Alston, J. Jeremías Incicco, Sukrit Singh, Melissa D. Stuchell-Brereton, Michael D. Ward, Maxwell I. Zimmerman, Neha Vithani, Daniel Griffith, Jason A. Wagoner, Gregory R. Bowman, Kathleen B. Hall, Andrea Soranno, Alex S. Holehouse
Publicado 2021

SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication

por Yuchen Zhang, Rui Guo, Sharon H. Kim, Hardik Shah, Shuting Zhang, Jin Hua Liang, Ying Fang, Matteo Gentili, Colin N. O’ Leary, Steven J. Elledge, Deborah T. Hung, Vamsi K. Mootha, Benjamin E. Gewurz
Publicado 2021