A single dose of replication-competent VSV-vectored vaccine expressing SARS-CoV-2 S1 protects against virus replication in a hamster model of severe COVID-19

por Delphine C. Malherbe, Drishya Kurup, Christoph Wirblich, Adam J. Ronk, Chad Mire, Natalia Kuzmina, Noor Shaik, Sivakumar Periasamy, Matthew A. Hyde, Julie M. Williams, Pei-Yong Shi, Matthias J. Schnell, Alexander Bukreyev
Publicado 2021

BRCA2 binding through a cryptic repeated motif to HSF2BP oligomers does not impact meiotic recombination

por Rania Ghouil, Simona Miron, Lieke Koornneef, Jasper Veerman, Maarten W. Paul, Marie-Hélène Le Du, Esther Sleddens-Linkels, Sari E. van Rossum-Fikkert, Yvette van Loon, Natalia Felipe-Medina, Alberto M. Pendas, Alex Maas, Jeroen Essers, Pierre Legrand, Willy M. Baarends, Roland Kanaar, Sophie Zinn-Justin, Alex N. Zelensky
Publicado 2021

Human embryonic stem cell-derived cardiomyocyte platform screens inhibitors of SARS-CoV-2 infection

por Thomas L. Williams, Maria T. Colzani, Robyn G. C. Macrae, Emma L. Robinson, Stuart Bloor, Edward J. D. Greenwood, Jun Ru Zhan, Gregory Strachan, Rhoda E. Kuc, Duuamene Nyimanu, Janet J. Maguire, Paul J. Lehner, Sanjay Sinha, Anthony P. Davenport
Publicado 2021

Substituted 1,2,3-triazoles: a new class of nitrification inhibitors

por Bethany I. Taggert, Charlie Walker, Deli Chen, Uta Wille
Publicado 2021

Whole genome sequencing of nearly isogenic WMI and WLI inbred rats identifies genes potentially involved in depression and stress reactivity

por Tristan V. de Jong, Panjun Kim, Victor Guryev, Megan K. Mulligan, Robert W. Williams, Eva E. Redei, Hao Chen
Publicado 2021

Fluoxetine increases brain MeCP2 immuno-positive cells in a female Mecp2 heterozygous mouse model of Rett syndrome through endogenous serotonin

por Claudia Villani, Mirjana Carli, Anna Maria Castaldo, Giuseppina Sacchetti, Roberto William Invernizzi
Publicado 2021

Structure-function analysis of purified proanthocyanidins reveals a role for polymer size in suppressing inflammatory responses

por Audrey Inge Schytz Andersen-Civil, Milla Marleena Leppä, Stig M. Thamsborg, Juha-Pekka Salminen, Andrew R. Williams
Publicado 2021

Faecal biomarkers in type 1 diabetes with and without diabetic nephropathy

por Signe Abitz Winther, Miia Maininki Mannerla, Marie Frimodt-Møller, Frederik Persson, Tine Willum Hansen, Markku Lehto, Sohvi Hörkkö, Michael Blaut, Carol Forsblom, Per-Henrik Groop, Peter Rossing
Publicado 2021

Identifying individuals with high risk of Alzheimer’s disease using polygenic risk scores

por Ganna Leonenko, Emily Baker, Joshua Stevenson-Hoare, Annerieke Sierksma, Mark Fiers, Julie Williams, Bart de Strooper, Valentina Escott-Price
Publicado 2021

Maternal control of visceral asymmetry evolution in Astyanax cavefish

por Li Ma, Mandy Ng, Janet Shi, Aniket V. Gore, Daniel Castranova, Brant M. Weinstein, William R. Jeffery
Publicado 2021

Nucleation of amorphous shear bands at nanotwins in boron suboxide

por Qi An, K. Madhav Reddy, Jin Qian, Kevin J. Hemker, Ming-Wei Chen, William A. Goddard III
Publicado 2016

G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis

por Annemarie Boleij, Payam Fathi, William Dalton, Ben Park, Xinqun Wu, David Huso, Jawara Allen, Sepideh Besharati, Robert A. Anders, Franck Housseau, Amanda E. Mackenzie, Laura Jenkins, Graeme. Milligan, Shaoguang Wu, Cynthia L. Sears
Publicado 2021

A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC

por Michael J. Schell, Mingli Yang, Jamie K. Teer, Fang Yin Lo, Anup Madan, Domenico Coppola, Alvaro N. A. Monteiro, Michael V. Nebozhyn, Binglin Yue, Andrey Loboda, Gabriel A. Bien-Willner, Danielle M. Greenawalt, Timothy J. Yeatman
Publicado 2016

6mer seed toxicity in tumor suppressive microRNAs

por Quan Q. Gao, William E. Putzbach, Andrea E. Murmann, Siquan Chen, Aishe A. Sarshad, Johannes M. Peter, Elizabeth T. Bartom, Markus Hafner, Marcus E. Peter
Publicado 2018

Germline AGO2 mutations impair RNA interference and human neurological development

por Davor Lessel, Daniela M. Zeitler, Margot R. F. Reijnders, Andriy Kazantsev, Fatemeh Hassani Nia, Alexander Bartholomäus, Victoria Martens, Astrid Bruckmann, Veronika Graus, Allyn McConkie-Rosell, Marie McDonald, Bernarda Lozic, Ee-Shien Tan, Erica Gerkes, Jessika Johannsen, Jonas Denecke, Aida Telegrafi, Evelien Zonneveld-Huijssoon, Henny H. Lemmink, Breana W. M. Cham, Tanja Kovacevic, Linda Ramsdell, Kimberly Foss, Diana Le Duc, Diana Mitter, Steffen Syrbe, Andreas Merkenschlager, Margje Sinnema, Bianca Panis, Joanna Lazier, Matthew Osmond, Taila Hartley, Jeremie Mortreux, Tiffany Busa, Chantal Missirian, Pankaj Prasun, Sabine Lüttgen, Ilaria Mannucci, Ivana Lessel, Claudia Schob, Stefan Kindler, John Pappas, Rachel Rabin, Marjolein Willemsen, Thatjana Gardeitchik, Katharina Löhner, Patrick Rump, Kerith-Rae Dias, Carey-Anne Evans, Peter Ian Andrews, Tony Roscioli, Han G. Brunner, Chieko Chijiwa, M. E. Suzanne Lewis, Rami Abou Jamra, David A. Dyment, Kym M. Boycott, Alexander P. A. Stegmann, Christian Kubisch, Ene-Choo Tan, Ghayda M. Mirzaa, Kirsty McWalter, Tjitske Kleefstra, Rolph Pfundt, Zoya Ignatova, Gunter Meister, Hans-Jürgen Kreienkamp
Publicado 2020

TFEB regulates murine liver cell fate during development and regeneration

por Nunzia Pastore, Tuong Huynh, Niculin J. Herz, Alessia Calcagni’, Tiemo J. Klisch, Lorenzo Brunetti, Kangho Ho Kim, Marco De Giorgi, Ayrea Hurley, Annamaria Carissimo, Margherita Mutarelli, Niya Aleksieva, Luca D’Orsi, William R. Lagor, David D. Moore, Carmine Settembre, Milton J. Finegold, Stuart J. Forbes, Andrea Ballabio
Publicado 2020

Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice

por Ja Young Kim-Muller, Jason Fan, Young Jung R. Kim, Seung-Ah Lee, Emi Ishida, William S. Blaner, Domenico Accili
Publicado 2016

A systematic comprehensive longitudinal evaluation of dietary factors associated with acute myocardial infarction and fatal coronary heart disease

por Soodabeh Milanlouei, Giulia Menichetti, Yanping Li, Joseph Loscalzo, Walter C. Willett, Albert-László Barabási
Publicado 2020

Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution

por Massimo Kube, Fabian Kohler, Elija Feigl, Baki Nagel-Yüksel, Elena M. Willner, Jonas J. Funke, Thomas Gerling, Pierre Stömmer, Maximilian N. Honemann, Thomas G. Martin, Sjors H. W. Scheres, Hendrik Dietz
Publicado 2020

Urban vacant lands impart hydrological benefits across city landscapes

por Christa Kelleher, Heather E. Golden, Sean Burkholder, William Shuster
Publicado 2020