Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases

por Rachel Fellows, Jérémy Denizot, Claudia Stellato, Alessandro Cuomo, Payal Jain, Elena Stoyanova, Szabina Balázsi, Zoltán Hajnády, Anke Liebert, Juri Kazakevych, Hector Blackburn, Renan Oliveira Corrêa, José Luís Fachi, Fabio Takeo Sato, Willian R. Ribeiro, Caroline Marcantonio Ferreira, Hélène Perée, Mariangela Spagnuolo, Raphaël Mattiuz, Csaba Matolcsi, Joana Guedes, Jonathan Clark, Marc Veldhoen, Tiziana Bonaldi, Marco Aurélio Ramirez Vinolo, Patrick Varga-Weisz
Publicado 2018

Escherichia coli FtsA forms lipid-bound minirings that antagonize lateral interactions between FtsZ protofilaments

por Marcin Krupka, Veronica W. Rowlett, Dustin Morado, Heidi Vitrac, Kara Schoenemann, Jun Liu, William Margolin
Publicado 2017

PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA

por Tovah A. Day, Jacob V. Layer, J. Patrick Cleary, Srijoy Guha, Kristen E. Stevenson, Trevor Tivey, Sunhee Kim, Anna C. Schinzel, Francesca Izzo, John Doench, David E. Root, William C. Hahn, Brendan D. Price, David M. Weinstock
Publicado 2017

Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines

por Eddie Cano-Gamez, Blagoje Soskic, Theodoros I. Roumeliotis, Ernest So, Deborah J. Smyth, Marta Baldrighi, David Willé, Nikolina Nakic, Jorge Esparza-Gordillo, Christopher G. C. Larminie, Paola G. Bronson, David F. Tough, Wendy C. Rowan, Jyoti S. Choudhary, Gosia Trynka
Publicado 2020

Gut microbiomes of wild great apes fluctuate seasonally in response to diet

por Allison L. Hicks, Kerry Jo Lee, Mara Couto-Rodriguez, Juber Patel, Rohini Sinha, Cheng Guo, Sarah H. Olson, Anton Seimon, Tracie A. Seimon, Alain U. Ondzie, William B. Karesh, Patricia Reed, Kenneth N. Cameron, W. Ian Lipkin, Brent L. Williams
Publicado 2018

January 2016 extensive summer melt in West Antarctica favoured by strong El Niño

por Julien P. Nicolas, Andrew M. Vogelmann, Ryan C. Scott, Aaron B. Wilson, Maria P. Cadeddu, David H. Bromwich, Johannes Verlinde, Dan Lubin, Lynn M. Russell, Colin Jenkinson, Heath H. Powers, Maciej Ryczek, Gregory Stone, Jonathan D. Wille
Publicado 2017

Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface

por C. Coral Domínguez-Medina, Marisol Pérez-Toledo, Anna E. Schager, Jennifer L. Marshall, Charlotte N. Cook, Saeeda Bobat, Hyea Hwang, Byeong Jae Chun, Erin Logan, Jack A. Bryant, Will M. Channell, Faye C. Morris, Sian E. Jossi, Areej Alshayea, Amanda E. Rossiter, Paul A. Barrow, William G. Horsnell, Calman A. MacLennan, Ian R. Henderson, Jeremy H. Lakey, James C. Gumbart, Constantino López-Macías, Vassiliy N. Bavro, Adam F. Cunningham
Publicado 2020

Genome-wide rare variant analysis for thousands of phenotypes in over 70,000 exomes from two cohorts

por Elizabeth T. Cirulli, Simon White, Robert W. Read, Gai Elhanan, William J. Metcalf, Francisco Tanudjaja, Donna M. Fath, Efren Sandoval, Magnus Isaksson, Karen A. Schlauch, Joseph J. Grzymski, James T. Lu, Nicole L. Washington
Publicado 2020

State-level tracking of COVID-19 in the United States

por H. Juliette T. Unwin, Swapnil Mishra, Valerie C. Bradley, Axel Gandy, Thomas A. Mellan, Helen Coupland, Jonathan Ish-Horowicz, Michaela A. C. Vollmer, Charles Whittaker, Sarah L. Filippi, Xiaoyue Xi, Mélodie Monod, Oliver Ratmann, Michael Hutchinson, Fabian Valka, Harrison Zhu, Iwona Hawryluk, Philip Milton, Kylie E. C. Ainslie, Marc Baguelin, Adhiratha Boonyasiri, Nick F. Brazeau, Lorenzo Cattarino, Zulma Cucunuba, Gina Cuomo-Dannenburg, Ilaria Dorigatti, Oliver D. Eales, Jeffrey W. Eaton, Sabine L. van Elsland, Richard G. FitzJohn, Katy A. M. Gaythorpe, William Green, Wes Hinsley, Benjamin Jeffrey, Edward Knock, Daniel J. Laydon, John Lees, Gemma Nedjati-Gilani, Pierre Nouvellet, Lucy Okell, Kris V. Parag, Igor Siveroni, Hayley A. Thompson, Patrick Walker, Caroline E. Walters, Oliver J. Watson, Lilith K. Whittles, Azra C. Ghani, Neil M. Ferguson, Steven Riley, Christl A. Donnelly, Samir Bhatt, Seth Flaxman
Publicado 2020

Genetic loci associated with heart rate variability and their effects on cardiac disease risk

por Ilja M. Nolte, M. Loretto Munoz, Vinicius Tragante, Azmeraw T. Amare, Rick Jansen, Ahmad Vaez, Benedikt von der Heyde, Christy L. Avery, Joshua C. Bis, Bram Dierckx, Jenny van Dongen, Stephanie M. Gogarten, Philippe Goyette, Jussi Hernesniemi, Ville Huikari, Shih-Jen Hwang, Deepali Jaju, Kathleen F. Kerr, Alexander Kluttig, Bouwe P. Krijthe, Jitender Kumar, Sander W. van der Laan, Leo-Pekka Lyytikäinen, Adam X. Maihofer, Arpi Minassian, Peter J. van der Most, Martina Müller-Nurasyid, Michel Nivard, Erika Salvi, James D. Stewart, Julian F. Thayer, Niek Verweij, Andrew Wong, Delilah Zabaneh, Mohammad H. Zafarmand, Abdel Abdellaoui, Sulayma Albarwani, Christine Albert, Alvaro Alonso, Foram Ashar, Juha Auvinen, Tomas Axelsson, Dewleen G. Baker, Paul I. W. de Bakker, Matteo Barcella, Riad Bayoumi, Rob J. Bieringa, Dorret Boomsma, Gabrielle Boucher, Annie R. Britton, Ingrid Christophersen, Andrea Dietrich, George B. Ehret, Patrick T. Ellinor, Markku Eskola, Janine F. Felix, John S. Floras, Oscar H. Franco, Peter Friberg, Maaike G. J. Gademan, Mark A. Geyer, Vilmantas Giedraitis, Catharina A. Hartman, Daiane Hemerich, Albert Hofman, Jouke-Jan Hottenga, Heikki Huikuri, Nina Hutri-Kähönen, Xavier Jouven, Juhani Junttila, Markus Juonala, Antti M. Kiviniemi, Jan A. Kors, Meena Kumari, Tatiana Kuznetsova, Cathy C. Laurie, Joop D. Lefrandt, Yong Li, Yun Li, Duanping Liao, Marian C. Limacher, Henry J. Lin, Cecilia M. Lindgren, Steven A. Lubitz, Anubha Mahajan, Barbara McKnight, Henriette Meyer zu Schwabedissen, Yuri Milaneschi, Nina Mononen, Andrew P. Morris, Mike A. Nalls, Gerjan Navis, Melanie Neijts, Kjell Nikus, Kari E. North, Daniel T. O'Connor, Johan Ormel, Siegfried Perz, Annette Peters, Bruce M. Psaty, Olli T. Raitakari, Victoria B. Risbrough, Moritz F. Sinner, David Siscovick, Johannes H. Smit, Nicholas L. Smith, Elsayed Z. Soliman, Nona Sotoodehnia, Jan A. Staessen, Phyllis K. Stein, Adrienne M. Stilp, Katarzyna Stolarz-Skrzypek, Konstantin Strauch, Johan Sundström, Cees A. Swenne, Ann-Christine Syvänen, Jean-Claude Tardif, Kent D. Taylor, Alexander Teumer, Timothy A. Thornton, Lesley E. Tinker, André G. Uitterlinden, Jessica van Setten, Andreas Voss, Melanie Waldenberger, Kirk C. Wilhelmsen, Gonneke Willemsen, Quenna Wong, Zhu-Ming Zhang, Alan B. Zonderman, Daniele Cusi, Michele K. Evans, Halina K. Greiser, Pim van der Harst, Mohammad Hassan, Erik Ingelsson, Marjo-Riitta Järvelin, Stefan Kääb, Mika Kähönen, Mika Kivimaki, Charles Kooperberg, Diana Kuh, Terho Lehtimäki, Lars Lind, Caroline M. Nievergelt, Chris J. O'Donnell, Albertine J. Oldehinkel, Brenda Penninx, Alexander P. Reiner, Harriëtte Riese, Arie M. van Roon, John D. Rioux, Jerome I. Rotter, Tamar Sofer, Bruno H. Stricker, Henning Tiemeier, Tanja G. M. Vrijkotte, Folkert W. Asselbergs, Bianca J. J. M. Brundel, Susan R. Heckbert, Eric A. Whitsel, Marcel den Hoed, Harold Snieder, Eco J. C. de Geus
Publicado 2017

Electro-osmotic capture and ionic discrimination of peptide and protein biomarkers with FraC nanopores

por Gang Huang, Kherim Willems, Misha Soskine, Carsten Wloka, Giovanni Maglia
Publicado 2017

Microbial community-level regulation explains soil carbon responses to long-term litter manipulations

por Katerina Georgiou, Rose Z. Abramoff, John Harte, William J. Riley, Margaret S. Torn
Publicado 2017

Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease

por Edmund J. Keliher, Yu-Xiang Ye, Gregory R. Wojtkiewicz, Aaron D. Aguirre, Benoit Tricot, Max L. Senders, Hannah Groenen, Francois Fay, Carlos Perez-Medina, Claudia Calcagno, Giuseppe Carlucci, Thomas Reiner, Yuan Sun, Gabriel Courties, Yoshiko Iwamoto, Hye-Yeong Kim, Cuihua Wang, John W. Chen, Filip K. Swirski, Hsiao-Ying Wey, Jacob Hooker, Zahi A. Fayad, Willem J. M. Mulder, Ralph Weissleder, Matthias Nahrendorf
Publicado 2017

Deconvolution of Buparlisib’s mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention

por Thomas Bohnacker, Andrea E. Prota, Florent Beaufils, John E. Burke, Anna Melone, Alison J. Inglis, Denise Rageot, Alexander M. Sele, Vladimir Cmiljanovic, Natasa Cmiljanovic, Katja Bargsten, Amol Aher, Anna Akhmanova, J. Fernando Díaz, Doriano Fabbro, Marketa Zvelebil, Roger L. Williams, Michel O. Steinmetz, Matthias P. Wymann
Publicado 2017

Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia

por Xi Jiang, Chao Hu, Kyle Ferchen, Ji Nie, Xiaolong Cui, Chih-Hong Chen, Liting Cheng, Zhixiang Zuo, William Seibel, Chunjiang He, Yixuan Tang, Jennifer R. Skibbe, Mark Wunderlich, William C. Reinhold, Lei Dong, Chao Shen, Stephen Arnovitz, Bryan Ulrich, Jiuwei Lu, Hengyou Weng, Rui Su, Huilin Huang, Yungui Wang, Chenying Li, Xi Qin, James C. Mulloy, Yi Zheng, Jiajie Diao, Jie Jin, Chong Li, Paul P. Liu, Chuan He, Yuan Chen, Jianjun Chen
Publicado 2017

Insufficient antibody validation challenges oestrogen receptor beta research

por Sandra Andersson, Mårten Sundberg, Nusa Pristovsek, Ahmed Ibrahim, Philip Jonsson, Borbala Katona, Carl-Magnus Clausson, Agata Zieba, Margareta Ramström, Ola Söderberg, Cecilia Williams, Anna Asplund
Publicado 2017

Author Correction: Chemokine receptor trafficking coordinates neutrophil clustering and dispersal at wounds in zebrafish

por Caroline Coombs, Antonios Georgantzoglou, Hazel A. Walker, Julian Patt, Nicole Merten, Hugo Poplimont, Elisabeth M. Busch-Nentwich, Sarah Williams, Christina Kotsi, Evi Kostenis, Milka Sarris
Publicado 2020

Imaging the square of the correlated two-electron wave function of a hydrogen molecule

por M. Waitz, R. Y. Bello, D. Metz, J. Lower, F. Trinter, C. Schober, M. Keiling, U. Lenz, M. Pitzer, K. Mertens, M. Martins, J. Viefhaus, S. Klumpp, T. Weber, L. Ph. H. Schmidt, J. B. Williams, M. S. Schöffler, V. V. Serov, A. S. Kheifets, L. Argenti, A. Palacios, F. Martín, T. Jahnke, R. Dörner
Publicado 2017

A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer

por Paola A. Betancur, Brian J. Abraham, Ying Y. Yiu, Stephen B. Willingham, Farnaz Khameneh, Mark Zarnegar, Angera H. Kuo, Kelly McKenna, Yoko Kojima, Nicholas J. Leeper, Po Ho, Phung Gip, Tomek Swigut, Richard I. Sherwood, Michael F. Clarke, George Somlo, Richard A. Young, Irving L. Weissman
Publicado 2017

Deletion of Topoisomerase 1 in excitatory neurons causes genomic instability and early onset neurodegeneration

por Giulia Fragola, Angela M. Mabb, Bonnie Taylor-Blake, Jesse K. Niehaus, William D. Chronister, Hanqian Mao, Jeremy M. Simon, Hong Yuan, Zibo Li, Michael J. McConnell, Mark J. Zylka
Publicado 2020