Misic, a general deep learning-based method for the high-throughput cell segmentation of complex bacterial communities

por Swapnesh Panigrahi, Dorothée Murat, Antoine Le Gall, Eugénie Martineau, Kelly Goldlust, Jean-Bernard Fiche, Sara Rombouts, Marcelo Nöllmann, Leon Espinosa, Tâm Mignot
Publicado 2021

Distinct population code for movement kinematics and changes of ongoing movements in human subthalamic nucleus

por Dennis London, Arash Fazl, Kalman Katlowitz, Marisol Soula, Michael H Pourfar, Alon Y Mogilner, Roozbeh Kiani
Publicado 2021

Early life experience sets hard limits on motor learning as evidenced from artificial arm use

por Roni O Maimon-Mor, Hunter R Schone, David Henderson Slater, A Aldo Faisal, Tamar R Makin
Publicado 2021

A distributed residue network permits conformational binding specificity in a conserved family of actin remodelers

por Theresa Hwang, Sara S Parker, Samantha M Hill, Meucci W Ilunga, Robert A Grant, Ghassan Mouneimne, Amy E Keating
Publicado 2021

A 3D adult zebrafish brain atlas (AZBA) for the digital age

por Justin W Kenney, Patrick E Steadman, Olivia Young, Meng Ting Shi, Maris Polanco, Saba Dubaishi, Kristopher Covert, Thomas Mueller, Paul W Frankland
Publicado 2021

Efficacy of FFP3 respirators for prevention of SARS-CoV-2 infection in healthcare workers

por Mark Ferris, Rebecca Ferris, Chris Workman, Eoin O'Connor, David A Enoch, Emma Goldesgeyme, Natalie Quinnell, Parth Patel, Jo Wright, Geraldine Martell, Christine Moody, Ashley Shaw, Christopher JR Illingworth, Nicholas J Matheson, Michael P Weekes
Publicado 2021

An essential, kinetoplastid-specific GDP-Fuc: β-D-Gal α-1,2-fucosyltransferase is located in the mitochondrion of Trypanosoma brucei

por Giulia Bandini, Sebastian Damerow, Maria Lucia Sempaio Guther, Hongjie Guo, Angela Mehlert, Jose Carlos Paredes Franco, Stephen Beverley, Michael AJ Ferguson
Publicado 2021

Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy

por Lisa M Strong, Chunmei Chang, Julia F Riley, C Alexander Boecker, Thomas G Flower, Cosmo Z Buffalo, Xuefeng Ren, Andrea KH Stavoe, Erika LF Holzbaur, James H Hurley
Publicado 2021

Early prediction of in-hospital death of COVID-19 patients: a machine-learning model based on age, blood analyses, and chest x-ray score

por Emirena Garrafa, Marika Vezzoli, Marco Ravanelli, Davide Farina, Andrea Borghesi, Stefano Calza, Roberto Maroldi
Publicado 2021

Electron cryo-tomography reveals the subcellular architecture of growing axons in human brain organoids

por Patrick C Hoffmann, Stefano L Giandomenico, Iva Ganeva, Michael R Wozny, Magdalena Sutcliffe, Madeline A Lancaster, Wanda Kukulski
Publicado 2021

Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics

por Michael I Barton, Stuart A MacGowan, Mikhail A Kutuzov, Omer Dushek, Geoffrey John Barton, P Anton van der Merwe
Publicado 2021

Adult stem cells and niche cells segregate gradually from common precursors that build the adult Drosophila ovary during pupal development

por Amy Reilein, Helen V Kogan, Rachel Misner, Karen Sophia Park, Daniel Kalderon
Publicado 2021

A small, computationally flexible network produces the phenotypic diversity of song recognition in crickets

por Jan Clemens, Stefan Schöneich, Konstantinos Kostarakos, R Matthias Hennig, Berthold Hedwig
Publicado 2021

The cell adhesion molecule Sdk1 shapes assembly of a retinal circuit that detects localized edges

por Pierre-Luc Rochon, Catherine Theriault, Aline Giselle Rangel Olguin, Arjun Krishnaswamy
Publicado 2021

The roles of history, chance, and natural selection in the evolution of antibiotic resistance

por Alfonso Santos-Lopez, Christopher W Marshall, Allison L Haas, Caroline Turner, Javier Rasero, Vaughn S Cooper
Publicado 2021

Common host variation drives malaria parasite fitness in healthy human red cells

por Emily R Ebel, Frans A Kuypers, Carrie Lin, Dmitri A Petrov, Elizabeth S Egan
Publicado 2021

PGFinder, a novel analysis pipeline for the consistent, reproducible, and high-resolution structural analysis of bacterial peptidoglycans

por Ankur V Patel, Robert D Turner, Aline Rifflet, Adelina E Acosta-Martin, Andrew Nichols, Milena M Awad, Dena Lyras, Ivo Gomperts Boneca, Marshall Bern, Mark O Collins, Stéphane Mesnage
Publicado 2021

Tracking the movement of discrete gating charges in a voltage-gated potassium channel

por Michael F Priest, Elizabeth EL Lee, Francisco Bezanilla
Publicado 2021

Disrupted PGR-B and ESR1 signaling underlies defective decidualization linked to severe preeclampsia

por Tamara Garrido-Gomez, Nerea Castillo-Marco, Mónica Clemente-Ciscar, Teresa Cordero, Irene Muñoz-Blat, Alicia Amadoz, Jorge Jimenez-Almazan, Rogelio Monfort-Ortiz, Reyes Climent, Alfredo Perales-Marin, Carlos Simon
Publicado 2021

Correction of amblyopia in cats and mice after the critical period

por Ming-fai Fong, Kevin R Duffy, Madison P Leet, Christian T Candler, Mark F Bear
Publicado 2021