Paths and pathways that generate cell-type heterogeneity and developmental progression in hematopoiesis

por Juliet R Girard, Lauren M Goins, Dung M Vuu, Mark S Sharpley, Carrie M Spratford, Shreya R Mantri, Utpal Banerjee
Publicado 2021

Protein kinase Cδ is essential for the IgG response against T-cell-independent type 2 antigens and commensal bacteria

por Saori Fukao, Kei Haniuda, Hiromasa Tamaki, Daisuke Kitamura
Publicado 2021

Determining the probability of hemiplasy in the presence of incomplete lineage sorting and introgression

por Mark S Hibbins, Matthew JS Gibson, Matthew W Hahn
Publicado 2020

The hepatic AMPK-TET1-SIRT1 axis regulates glucose homeostasis

por Chunbo Zhang, Tianyu Zhong, Yuanyuan Li, Xianfeng Li, Xiaopeng Yuan, Linlin Liu, Weilin Wu, Jing Wu, Ye Wu, Rui Liang, Xinhua Xie, Chuanchuan Kang, Yuwen Liu, Zhonghong Lai, Jianbo Xiao, Zhixian Tang, Riqun Jin, Yan Wang, Yongwei Xiao, Jin Zhang, Jian Li, Qian Liu, Zhongsheng Sun, Jianing Zhong
Publicado 2021

Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly

por María J Conde-Dusman, Partha N Dey, Óscar Elía-Zudaire, Luis G Rabaneda, Carmen García-Lira, Teddy Grand, Victor Briz, Eric R Velasco, Raül Andero, Sergio Niñerola, Angel Barco, Pierre Paoletti, John F Wesseling, Fabrizio Gardoni, Steven J Tavalin, Isabel Perez-Otaño
Publicado 2021

Quantitative spatial and temporal assessment of regulatory element activity in zebrafish

por Shipra Bhatia, Dirk Jan Kleinjan, Kirsty Uttley, Anita Mann, Nefeli Dellepiane, Wendy A Bickmore
Publicado 2021

Remodeling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte division

por Jin Rong Ow, Matias J Caldez, Gözde Zafer, Juat Chin Foo, Hong Yu Li, Soumita Ghosh, Heike Wollmann, Amaury Cazenave-Gassiot, Chee Bing Ong, Markus R Wenk, Weiping Han, Hyungwon Choi, Philipp Kaldis
Publicado 2020

Single-cell RNA-seq reveals transcriptomic heterogeneity mediated by host–pathogen dynamics in lymphoblastoid cell lines

por Elliott D SoRelle, Joanne Dai, Emmanuela N Bonglack, Emma M Heckenberg, Jeffrey Y Zhou, Stephanie N Giamberardino, Jeffrey A Bailey, Simon G Gregory, Cliburn Chan, Micah A Luftig
Publicado 2021

Disturbed retinoid metabolism upon loss of rlbp1a impairs cone function and leads to subretinal lipid deposits and photoreceptor degeneration in the zebrafish retina

por Domino K Schlegel, Srinivasagan Ramkumar, Johannes von Lintig, Stephan CF Neuhauss
Publicado 2021

Correction: Single-cell RNA-seq reveals transcriptomic heterogeneity mediated by host–pathogen dynamics in lymphoblastoid cell lines

por Elliott D SoRelle, Joanne Dai, Emmanuela N Bonglack, Emma M Heckenberg, Jeffrey Y Zhou, Stephanie N Giamberardino, Jeffrey A Bailey, Simon G Gregory, Cliburn Chan, Micah A Luftig
Publicado 2021

The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice

por Michael Jonathan Lehrke, Michael Jeremy Shapiro, Matthew J Rajcula, Madeleine M Kennedy, Shaylene A McCue, Kay L Medina, Virginia Smith Shapiro
Publicado 2021

Reshaping of bacterial molecular hydrogen metabolism contributes to the outgrowth of commensal E. coli during gut inflammation

por Elizabeth R Hughes, Maria G Winter, Laice Alves da Silva, Matthew K Muramatsu, Angel G Jimenez, Caroline C Gillis, Luisella Spiga, Rachael B Chanin, Renato L Santos, Wenhan Zhu, Sebastian E Winter
Publicado 2021

Short-chain fatty acids activate acetyltransferase p300

por Sydney P Thomas, John M Denu
Publicado 2021

Proposed therapy, developed in a Pcdh15-deficient mouse, for progressive loss of vision in human Usher syndrome

por Saumil Sethna, Wadih M Zein, Sehar Riaz, Arnaud PJ Giese, Julie M Schultz, Todd Duncan, Robert B Hufnagel, Carmen C Brewer, Andrew J Griffith, T Michael Redmond, Saima Riazuddin, Thomas B Friedman, Zubair M Ahmed
Publicado 2021

Spatial alanine metabolism determines local growth dynamics of Escherichia coli colonies

por Francisco Díaz-Pascual, Martin Lempp, Kazuki Nosho, Hannah Jeckel, Jeanyoung K Jo, Konstantin Neuhaus, Raimo Hartmann, Eric Jelli, Mads Frederik Hansen, Alexa Price-Whelan, Lars EP Dietrich, Hannes Link, Knut Drescher
Publicado 2021

Met and Cxcr4 cooperate to protect skeletal muscle stem cells against inflammation-induced damage during regeneration

por Ines Lahmann, Joscha Griger, Jie-Shin Chen, Yao Zhang, Markus Schuelke, Carmen Birchmeier
Publicado 2021

Finger somatotopy is preserved after tetraplegia but deteriorates over time

por Sanne Kikkert, Dario Pfyffer, Michaela Verling, Patrick Freund, Nicole Wenderoth
Publicado 2021

Spatial modulation of individual behaviors enables an ordered structure of diverse phenotypes during bacterial group migration

por Yang Bai, Caiyun He, Pan Chu, Junjiajia Long, Xuefei Li, Xiongfei Fu
Publicado 2021

The inner mechanics of rhodopsin guanylyl cyclase during cGMP-formation revealed by real-time FTIR spectroscopy

por Paul Fischer, Shatanik Mukherjee, Enrico Peter, Matthias Broser, Franz Bartl, Peter Hegemann
Publicado 2021

The role of TAp63γ and P53 point mutations in regulating DNA repair, mutational susceptibility and invasion of bladder cancer cells

por Hsiang-Tsui Wang, Hyun-Wook Lee, Mao-wen Weng, Yan Liu, William C Huang, Herbert Lepor, Xue-Ru Wu, Moon-shong Tang
Publicado 2021