mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia

por Soyeon Lim, You-Joung Kim, Sooyeon Park, Ji-heon Choi, Young Hoon Sung, Katsuhiko Nishimori, Zbynek Kozmik, Han-Woong Lee, Jin Woo Kim
Publicado 2021

Spatiotemporal control of cell cycle acceleration during axolotl spinal cord regeneration

por Emanuel Cura Costa, Leo Otsuki, Aida Rodrigo Albors, Elly M Tanaka, Osvaldo Chara
Publicado 2021

Parallel functional testing identifies enhancers active in early postnatal mouse brain

por Jason T Lambert, Linda Su-Feher, Karol Cichewicz, Tracy L Warren, Iva Zdilar, Yurong Wang, Kenneth J Lim, Jessica L Haigh, Sarah J Morse, Cesar P Canales, Tyler W Stradleigh, Erika Castillo Palacios, Viktoria Haghani, Spencer D Moss, Hannah Parolini, Diana Quintero, Diwash Shrestha, Daniel Vogt, Leah C Byrne, Alex S Nord
Publicado 2021

Structural insight into the dual function of LbpB in mediating Neisserial pathogenesis

por Ravi Yadav, Srinivas Govindan, Courtney Daczkowski, Andrew Mesecar, Srinivas Chakravarthy, Nicholas Noinaj
Publicado 2021

Dynamics and variability in the pleiotropic effects of adaptation in laboratory budding yeast populations

por Christopher W Bakerlee, Angela M Phillips, Alex N Nguyen Ba, Michael M Desai
Publicado 2021

Deep evolutionary origin of gamete-directed zygote activation by KNOX/BELL transcription factors in green plants

por Tetsuya Hisanaga, Shota Fujimoto, Yihui Cui, Katsutoshi Sato, Ryosuke Sano, Shohei Yamaoka, Takayuki Kohchi, Frédéric Berger, Keiji Nakajima
Publicado 2021

Tumor-derived extracellular vesicles regulate tumor-infiltrating regulatory T cells via the inhibitory immunoreceptor CD300a

por Yuta Nakazawa, Nanako Nishiyama, Hitoshi Koizumi, Kazumasa Kanemaru, Chigusa Nakahashi-Oda, Akira Shibuya
Publicado 2021

TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states

por Simiao Xu, Yangyang Liu, Ruixiang Hu, Min Wang, Oliver Stöhr, Yibo Xiong, Liang Chen, Hong Kang, Lingyun Zheng, Songjie Cai, Li He, Cunchuan Wang, Kyle D Copps, Morris F White, Ji Miao
Publicado 2021

Protein phosphatase 1 in association with Bud14 inhibits mitotic exit in Saccharomyces cerevisiae

por Dilara Kocakaplan, Hüseyin Karabürk, Cansu Dilege, Idil Kirdök, Seyma Nur Bektas, Ayse Koca Caydasi
Publicado 2021

Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor

por Peter Ahorukomeye, Maria M Disotuar, Joanna Gajewiak, Santhosh Karanth, Maren Watkins, Samuel D Robinson, Paula Flórez Salcedo, Nicholas A Smith, Brian J Smith, Amnon Schlegel, Briony E Forbes, Baldomero Olivera, Danny Hung-Chieh Chou, Helena Safavi-Hemami
Publicado 2019

The influence of biological and lifestyle factors on circulating cell-free DNA in blood plasma

por Nicole Laurencia Yuwono, Kristina Warton, Caroline Elizabeth Ford
Publicado 2021

NHR-8 and P-glycoproteins uncouple xenobiotic resistance from longevity in chemosensory C. elegans mutants

por Gabriel A Guerrero, Maxime J Derisbourg, Felix AMC Mayr, Laura E Wester, Marco Giorda, J Eike Dinort, Matías D Hartman, Klara Schilling, María José Alonso-De Gennaro, Ryan J Lu, Bérénice A Benayoun, Martin S Denzel
Publicado 2021

Preventing collateral damage

por Harry Quon, Fred Bunz
Publicado 2021

IFN-γ mediates Paneth cell death via suppression of mTOR

por Alessandra Araujo, Alexandra Safronova, Elise Burger, Américo López-Yglesias, Shilpi Giri, Ellie T Camanzo, Andrew T Martin, Sergei Grivennikov, Felix Yarovinsky
Publicado 2021

Intergenerational adaptations to stress are evolutionarily conserved, stress-specific, and have deleterious trade-offs

por Nicholas O Burton, Alexandra Willis, Kinsey Fisher, Fabian Braukmann, Jonathan Price, Lewis Stevens, L Ryan Baugh, Aaron Reinke, Eric A Miska
Publicado 2021

3D cell neighbour dynamics in growing pseudostratified epithelia

por Harold Fernando Gómez, Mathilde Sabine Dumond, Leonie Hodel, Roman Vetter, Dagmar Iber
Publicado 2021

Behavioral control by depolarized and hyperpolarized states of an integrating neuron

por Aylesse Sordillo, Cornelia I Bargmann
Publicado 2021

Aversive stimuli bias corticothalamic responses to motivationally significant cues

por Federica Lucantonio, Eunyoung Kim, Zhixiao Su, Anna J Chang, Bilal A Bari, Jeremiah Y Cohen
Publicado 2021

Sex difference analyses under scrutiny

por Colby J Vorland
Publicado 2021

Emerging dynamics from high-resolution spatial numerical epidemics

por Olivier Thomine, Samuel Alizon, Corentin Boennec, Marc Barthelemy, Mircea Sofonea
Publicado 2021