Neutrophil-mediated oxidative stress and albumin structural damage predict COVID-19-associated mortality

por Mohamed A Badawy, Basma A Yasseen, Riem M El-Messiery, Engy A Abdel-Rahman, Aya A Elkhodiry, Azza G Kamel, Hajar El-sayed, Asmaa M Shedra, Rehab Hamdy, Mona Zidan, Diaa Al-Raawi, Mahmoud Hammad, Nahla Elsharkawy, Mohamed El Ansary, Ahmed Al-Halfawy, Alaa Elhadad, Ashraf Hatem, Sherif Abouelnaga, Laura L Dugan, Sameh Saad Ali
Publicado 2021

Mapping the visual world to the human brain

por Betina Ip, Holly Bridge
Publicado 2021

Population receptive fields in nonhuman primates from whole-brain fMRI and large-scale neurophysiology in visual cortex

por P Christiaan Klink, Xing Chen, Wim Vanduffel, Pieter R Roelfsema
Publicado 2021

Topological network analysis of patient similarity for precision management of acute blood pressure in spinal cord injury

por Abel Torres-Espín, Jenny Haefeli, Reza Ehsanian, Dolores Torres, Carlos A Almeida, J Russell Huie, Austin Chou, Dmitriy Morozov, Nicole Sanderson, Benjamin Dirlikov, Catherine G Suen, Jessica L Nielson, Nikos Kyritsis, Debra D Hemmerle, Jason F Talbott, Geoffrey T Manley, Sanjay S Dhall, William D Whetstone, Jacqueline C Bresnahan, Michael S Beattie, Stephen L McKenna, Jonathan Z Pan, Adam R Ferguson, The TRACK-SCI Investigators
Publicado 2021

Type 1 polyisoprenoid diphosphate phosphatase modulates geranylgeranyl-mediated control of HMG CoA reductase and UBIAD1

por Rania Elsabrouty, Youngah Jo, Seonghwan Hwang, Dong-Jae Jun, Russell A DeBose-Boyd
Publicado 2021

Columnar processing of border ownership in primate visual cortex

por Tom P Franken, John H Reynolds
Publicado 2021

Impaired mRNA splicing and proteostasis in preadipocytes in obesity-related metabolic disease

por Julia Sánchez-Ceinos, Rocío Guzmán-Ruiz, Oriol Alberto Rangel-Zúñiga, Jaime López-Alcalá, Elena Moreno-Caño, Mercedes Del Río-Moreno, Juan Luis Romero-Cabrera, Pablo Pérez-Martínez, Elsa Maymo-Masip, Joan Vendrell, Sonia Fernández-Veledo, José Manuel Fernández-Real, Jurga Laurencikiene, Mikael Rydén, Antonio Membrives, Raul M Luque, José López-Miranda, María M Malagón
Publicado 2021

Maturation of persistent and hyperpolarization-activated inward currents shapes the differential activation of motoneuron subtypes during postnatal development

por Simon A Sharples, Gareth B Miles
Publicado 2021

Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation

por Xiao-Tong Lin, Hong-Qiang Yu, Lei Fang, Ye Tan, Ze-Yu Liu, Di Wu, Jie Zhang, Hao-Jun Xiong, Chuan-Ming Xie
Publicado 2021

Phases of cortical actomyosin dynamics coupled to the neuroblast polarity cycle

por Chet Huan Oon, Kenneth E Prehoda
Publicado 2021

Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation

por Jesse M Hansen, Avital Horowitz, Eric M Lynch, Daniel P Farrell, Joel Quispe, Frank DiMaio, Justin M Kollman
Publicado 2021

REST/NRSF drives homeostatic plasticity of inhibitory synapses in a target-dependent fashion

por Cosimo Prestigio, Daniele Ferrante, Antonella Marte, Alessandra Romei, Gabriele Lignani, Franco Onofri, Pierluigi Valente, Fabio Benfenati, Pietro Baldelli
Publicado 2021

Genetic, cellular, and structural characterization of the membrane potential-dependent cell-penetrating peptide translocation pore

por Evgeniya Trofimenko, Gianvito Grasso, Mathieu Heulot, Nadja Chevalier, Marco A Deriu, Gilles Dubuis, Yoan Arribat, Marc Serulla, Sebastien Michel, Gil Vantomme, Florine Ory, Linh Chi Dam, Julien Puyal, Francesca Amati, Anita Lüthi, Andrea Danani, Christian Widmann
Publicado 2021

A computational screen for alternative genetic codes in over 250,000 genomes

por Yekaterina Shulgina, Sean R Eddy
Publicado 2021

The Lyme disease agent co-opts adiponectin receptor-mediated signaling in its arthropod vector

por Xiaotian Tang, Yongguo Cao, Gunjan Arora, Jesse Hwang, Andaleeb Sajid, Courtney L Brown, Sameet Mehta, Alejandro Marín-López, Yu-Min Chuang, Ming-Jie Wu, Hongwei Ma, Utpal Pal, Sukanya Narasimhan, Erol Fikrig
Publicado 2021

Silencing long ascending propriospinal neurons after spinal cord injury improves hindlimb stepping in the adult rat

por Courtney T Shepard, Amanda M Pocratsky, Brandon L Brown, Morgan A Van Rijswijck, Rachel M Zalla, Darlene A Burke, Johnny R Morehouse, Amberley S Riegler, Scott R Whittemore, David SK Magnuson
Publicado 2021

Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation

por Drew Wilfahrt, Rachael L Philips, Jyoti Lama, Monika Kizerwetter, Michael Jeremy Shapiro, Shaylene A McCue, Madeleine M Kennedy, Matthew J Rajcula, Hu Zeng, Virginia Smith Shapiro
Publicado 2021

Single-cell-level protein analysis revealing the roles of autoantigen-reactive B lymphocytes in autoimmune disease and the murine model

por Takemichi Fukasawa, Ayumi Yoshizaki, Satoshi Ebata, Asako Yoshizaki-Ogawa, Yoshihide Asano, Atsushi Enomoto, Kiyoshi Miyagawa, Yutaka Kazoe, Kazuma Mawatari, Takehiko Kitamori, Shinichi Sato
Publicado 2021

Growth-dependent signals drive an increase in early G1 cyclin concentration to link cell cycle entry with cell growth

por Robert A Sommer, Jerry T DeWitt, Raymond Tan, Douglas R Kellogg
Publicado 2021

Ct threshold values, a proxy for viral load in community SARS-CoV-2 cases, demonstrate wide variation across populations and over time

por A Sarah Walker, Emma Pritchard, Thomas House, Julie V Robotham, Paul J Birrell, Iain Bell, John I Bell, John N Newton, Jeremy Farrar, Ian Diamond, Ruth Studley, Jodie Hay, Karina-Doris Vihta, Timothy EA Peto, Nicole Stoesser, Philippa C Matthews, David W Eyre, Koen B Pouwels, COVID-19 Infection Survey team
Publicado 2021