A multiscale approach to modelling drug metabolism by membrane-bound cytochrome P450 enzymes.

por Richard Lonsdale, Sarah L Rouse, Mark S P Sansom, Adrian J Mulholland
Publicado 2014

Exploration of the structural requirements of Aurora Kinase B inhibitors by a combined QSAR, modelling and molecular simulation approach

por Sajda Ashraf, Kara E. Ranaghan, Christopher J. Woods, Adrian J. Mulholland, Zaheer Ul-Haq
Publicado 2021

Dynamical origins of heat capacity changes in enzyme-catalysed reactions

por Marc W. van der Kamp, Erica J. Prentice, Kirsty L. Kraakman, Michael Connolly, Adrian J. Mulholland, Vickery L. Arcus
Publicado 2018

Maintaining and breaking symmetry in homomeric coiled-coil assemblies

por Guto G. Rhys, Christopher W. Wood, Eric J. M. Lang, Adrian J. Mulholland, R. Leo Brady, Andrew R. Thomson, Derek N. Woolfson
Publicado 2018

Structural resolution of switchable states of a de novo peptide assembly

por William M. Dawson, Eric J. M. Lang, Guto G. Rhys, Kathryn L. Shelley, Christopher Williams, R. Leo Brady, Matthew P. Crump, Adrian J. Mulholland, Derek N. Woolfson
Publicado 2021

Construction and in vivo assembly of a catalytically proficient and hyperthermostable de novo enzyme

por Daniel W. Watkins, Jonathan M. X. Jenkins, Katie J. Grayson, Nicola Wood, Jack W. Steventon, Kristian K. Le Vay, Matthew I. Goodwin, Anna S. Mullen, Henry J. Bailey, Matthew P. Crump, Fraser MacMillan, Adrian J. Mulholland, Gus Cameron, Richard B. Sessions, Stephen Mann, J. L. Ross Anderson
Publicado 2017