DNAJB6b-enriched small extracellular vesicles decrease polyglutamine aggregation in in vitro and in vivo models of Huntington disease

por Bhagyashree S. Joshi, Sameh A. Youssef, Reinier Bron, Alain de Bruin, Harm H. Kampinga, Inge S. Zuhorn
Publicado 2021

Acute systemic loss of Mad2 leads to intestinal atrophy in adult mice

por Klaske M. Schukken, Yinan Zhu, Petra L. Bakker, Mirjam H. Koster, Liesbeth Harkema, Sameh A. Youssef, Alain de Bruin, Floris Foijer
Publicado 2021

Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia

por Marcela Doktorova, Irene Zwarts, Tim van Zutphen, Theo H. van Dijk, Vincent W. Bloks, Liesbeth Harkema, Alain de Bruin, Michael Downes, Ronald M. Evans, Henkjan J. Verkade, Johan W. Jonker
Publicado 2017

Preoperative fasting protects against renal ischemia-reperfusion injury in aged and overweight mice.

por Franny Jongbloed, Ron W F de Bruin, Jeroen L A Pennings, César Payán-Gómez, Sandra van den Engel, Conny T van Oostrom, Alain de Bruin, Jan H J Hoeijmakers, Harry van Steeg, Jan N M IJzermans, Martijn E T Dollé
Publicado 2014

The hepatocyte IKK:NF-κB axis promotes liver steatosis by stimulating de novo lipogenesis and cholesterol synthesis

por Andries Heida, Nanda Gruben, Leen Catrysse, Martijn Koehorst, Mirjam Koster, Niels J. Kloosterhuis, Albert Gerding, Rick Havinga, Vincent W. Bloks, Laura Bongiovanni, Justina C. Wolters, Theo van Dijk, Geert van Loo, Alain de Bruin, Folkert Kuipers, Debby P.Y. Koonen, Bart van de Sluis
Publicado 2021