Roles of Macrophages in Atherogenesis

por Lia Farahi, Satyesh K. Sinha, Aldons J. Lusis
Publicado 2021

Machine Learning Reveals Time-Varying Microbial Predictors with Complex Effects on Glucose Regulation

por Oliver Aasmets, Kreete Lüll, Jennifer M. Lang, Calvin Pan, Johanna Kuusisto, Krista Fischer, Markku Laakso, Aldons J. Lusis, Elin Org
Publicado 2021

Natural variation of macrophage activation as disease-relevant phenotype predictive of inflammation and cancer survival

por Konrad Buscher, Erik Ehinger, Pritha Gupta, Akula Bala Pramod, Dennis Wolf, George Tweet, Calvin Pan, Charles D. Mills, Aldons J. Lusis, Klaus Ley
Publicado 2017

Suppression of inflammatory arthritis in human serum paraoxonase 1 transgenic mice

por Christina Charles-Schoeman, Jennifer Wang, Ani Shahbazian, Yuen Yin Lee, Xiaoyan Wang, Victor Grijalva, Ernest Brahn, Diana M. Shih, Asokan Devarajan, Christy Montano, Aldons J. Lusis, Srinivasa T. Reddy
Publicado 2020

Impact of Individual Traits, Saturated Fat, and Protein Source on the Gut Microbiome

por Jennifer M. Lang, Calvin Pan, Rita M. Cantor, W. H. Wilson Tang, Jose Carlos Garcia-Garcia, Ira Kurtz, Stanley L. Hazen, Nathalie Bergeron, Ronald M. Krauss, Aldons J. Lusis
Publicado 2018

NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice

por Fangfei Guo, Marcus Seldin, Miklós Péterfy, Sarada Charugundla, Zhiqiang Zhou, Stephen D. Lee, Alice Mouton, Prashant Rajbhandari, Wenchao Zhang, Matteo Pellegrini, Peter Tontonoz, Aldons J. Lusis, Diana M. Shih
Publicado 2021

Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice

por Zhengyi Zhang, An-Chieh Feng, David Salisbury, Xin Liu, Xiaohui Wu, Jason Kim, Irina Lapina, Dan Wang, Brennan Lee, Josue Fraga, Calvin Pan, Kevin J. Williams, Aldons J. Lusis, Phil Scumpia, Tamer Sallam
Publicado 2020

Allelic variation on murine chromosome 11 modifies host inflammatory responses and resistance to Bacillus anthracis.

por Jill K Terra, Bryan France, Christopher K Cote, Amy Jenkins, Joel A Bozue, Susan L Welkos, Ragini Bhargava, Chi-Lee Ho, Margarete Mehrabian, Calvin Pan, Aldons J Lusis, Richard C Davis, Steven M LeVine, Kenneth A Bradley
Publicado 2011

XX sex chromosome complement promotes atherosclerosis in mice

por Yasir AlSiraj, Xuqi Chen, Sean E. Thatcher, Ryan E. Temel, Lei Cai, Eric Blalock, Wendy Katz, Heba M. Ali, Michael Petriello, Pan Deng, Andrew J. Morris, Xuping Wang, Aldons J. Lusis, Arthur P. Arnold, Karen Reue, Katherine Thompson, Patrick Tso, Lisa A. Cassis
Publicado 2019

Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

por David Z. Pan, Kristina M. Garske, Marcus Alvarez, Yash V. Bhagat, James Boocock, Elina Nikkola, Zong Miao, Chelsea K. Raulerson, Rita M. Cantor, Mete Civelek, Craig A. Glastonbury, Kerrin S. Small, Michael Boehnke, Aldons J. Lusis, Janet S. Sinsheimer, Karen L. Mohlke, Markku Laakso, Päivi Pajukanta, Arthur Ko
Publicado 2018

Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

por David Z. Pan, Kristina M. Garske, Marcus Alvarez, Yash V. Bhagat, James Boocock, Elina Nikkola, Zong Miao, Chelsea K. Raulerson, Rita M. Cantor, Mete Civelek, Craig A. Glastonbury, Kerrin S. Small, Michael Boehnke, Aldons J. Lusis, Janet S. Sinsheimer, Karen L. Mohlke, Markku Laakso, Päivi Pajukanta, Arthur Ko
Publicado 2018

FAM13A affects body fat distribution and adipocyte function

por Mohsen Fathzadeh, Jiehan Li, Abhiram Rao, Naomi Cook, Indumathi Chennamsetty, Marcus Seldin, Xiang Zhou, Panjamaporn Sangwung, Michael J. Gloudemans, Mark Keller, Allan Attie, Jing Yang, Martin Wabitsch, Ivan Carcamo-Orive, Yuko Tada, Aldons J. Lusis, Myung Kyun Shin, Cliona M. Molony, Tracey McLaughlin, Gerald Reaven, Stephen B. Montgomery, Dermot Reilly, Thomas Quertermous, Erik Ingelsson, Joshua W. Knowles
Publicado 2020

An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease

por Ariella T. Cohain, William T. Barrington, Daniel M. Jordan, Noam D. Beckmann, Carmen A. Argmann, Sander M. Houten, Alexander W. Charney, Raili Ermel, Katyayani Sukhavasi, Oscar Franzen, Simon Koplev, Carl Whatling, Gillian M. Belbin, Jialiang Yang, Ke Hao, Eimear E. Kenny, Zhidong Tu, Jun Zhu, Li-Ming Gan, Ron Do, Chiara Giannarelli, Jason C. Kovacic, Arno Ruusalepp, Aldons J. Lusis, Johan L. M. Bjorkegren, Eric E. Schadt
Publicado 2021

Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells

por Juliane Hitzel, Eunjee Lee, Yi Zhang, Sofia Iris Bibli, Xiaogang Li, Sven Zukunft, Beatrice Pflüger, Jiong Hu, Christoph Schürmann, Andrea Estefania Vasconez, James A. Oo, Adelheid Kratzer, Sandeep Kumar, Flávia Rezende, Ivana Josipovic, Dominique Thomas, Hector Giral, Yannick Schreiber, Gerd Geisslinger, Christian Fork, Xia Yang, Fragiska Sigala, Casey E. Romanoski, Jens Kroll, Hanjoong Jo, Ulf Landmesser, Aldons J. Lusis, Dmitry Namgaladze, Ingrid Fleming, Matthias S. Leisegang, Jun Zhu, Ralf P. Brandes
Publicado 2018

Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure

por Pablo Cordero, Victoria N. Parikh, Elizabeth T. Chin, Ayca Erbilgin, Michael J. Gloudemans, Ching Shang, Yong Huang, Alex C. Chang, Kevin S. Smith, Frederick Dewey, Kathia Zaleta, Michael Morley, Jeff Brandimarto, Nicole Glazer, Daryl Waggott, Aleksandra Pavlovic, Mingming Zhao, Christine S. Moravec, W. H. Wilson Tang, Jamie Skreen, Christine Malloy, Sridhar Hannenhalli, Hongzhe Li, Scott Ritter, Mingyao Li, Daniel Bernstein, Andrew Connolly, Hakon Hakonarson, Aldons J. Lusis, Kenneth B. Margulies, Anna A. Depaoli-Roach, Stephen B. Montgomery, Matthew T. Wheeler, Thomas Cappola, Euan A. Ashley
Publicado 2019