Mining the transcriptome for rare disease therapies: a comparison of the efficiencies of two data mining approaches and a targeted cell-based drug screen

por A. J. Mears, S. C. Schock, J. Hadwen, S. Putos, D. Dyment, K. M. Boycott, Alex MacKenzie
Publicado 2017

High-throughput kinome-RNAi screen identifies protein kinase R activator (PACT) as a novel genetic modifier of CUG foci integrity in myotonic dystrophy type 1 (DM1).

por Nafisa Neault, Sean O'Reilly, Aiman Tariq Baig, Julio Plaza-Diaz, Mehrdad Azimi, Faraz Farooq, Stephen D Baird, Alex MacKenzie
Publicado 2021