Neutrophil recruitment limited by high-affinity bent β2 integrin binding ligand in cis

par Zhichao Fan, Sara McArdle, Alex Marki, Zbigniew Mikulski, Edgar Gutierrez, Britta Engelhardt, Urban Deutsch, Mark Ginsberg, Alex Groisman, Klaus Ley
Publié 2016

Endothelial Heparan Sulfate Mediates Hepatic Neutrophil Trafficking and Injury during Staphylococcus aureus Sepsis

par Gregory J. Golden, Alejandro Gómez Toledo, Alex Marki, James T. Sorrentino, Claire Morris, Raquel J. Riley, Charlotte Spliid, Qiongyu Chen, Ingrid Cornax, Nathan E. Lewis, Nissi Varki, Dzung Le, Johan Malmström, Christofer Karlsson, Klaus Ley, Victor Nizet, Jeffrey D. Esko
Publié 2021

A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense

par Dennis Wolf, Nathaly Anto-Michel, Hermann Blankenbach, Ansgar Wiedemann, Konrad Buscher, Jan David Hohmann, Bock Lim, Marina Bäuml, Alex Marki, Maximilian Mauler, Daniel Duerschmied, Zhichao Fan, Holger Winkels, Daniel Sidler, Philipp Diehl, Dirk M Zajonc, Ingo Hilgendorf, Peter Stachon, Timoteo Marchini, Florian Willecke, Maximilian Schell, Björn Sommer, Constantin von zur Muhlen, Jochen Reinöhl, Teresa Gerhardt, Edward F. Plow, Valentin Yakubenko, Peter Libby, Christoph Bode, Klaus Ley, Karlheinz Peter, Andreas Zirlik
Publié 2018