Beyond the List: Bioagent-Agnostic Signatures Could Enable a More Flexible and Resilient Biodefense Posture Than an Approach Based on Priority Agent Lists Alone

par Owen P. Leiser, Errett C. Hobbs, Amy C. Sims, George W. Korch, Karen L. Taylor
Publié 2021

Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation

par Joshua M. Thornbrough, Babal K. Jha, Boyd Yount, Stephen A. Goldstein, Yize Li, Ruth Elliott, Amy C. Sims, Ralph S. Baric, Robert H. Silverman, Susan R. Weiss
Publié 2016

Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis

par Vineet D. Menachery, Lisa E. Gralinski, Hugh D. Mitchell, Kenneth H. Dinnon, Sarah R. Leist, Boyd L. Yount, Rachel L. Graham, Eileen T. McAnarney, Kelly G. Stratton, Adam S. Cockrell, Kari Debbink, Amy C. Sims, Katrina M. Waters, Ralph S. Baric
Publié 2017

Unfolded Protein Response Inhibition Reduces Middle East Respiratory Syndrome Coronavirus-Induced Acute Lung Injury

par Amy C. Sims, Hugh D. Mitchell, Lisa E. Gralinski, Jennifer E. Kyle, Kristin E. Burnum-Johnson, Mariam Lam, M. Leslie Fulcher, Ande West, Richard D. Smith, Scott H. Randell, Thomas O. Metz, Timothy P. Sheahan, Katrina M. Waters, Ralph S. Baric
Publié 2021

MPLEx: a Robust and Universal Protocol for Single-Sample Integrative Proteomic, Metabolomic, and Lipidomic Analyses

par Ernesto S. Nakayasu, Carrie D. Nicora, Amy C. Sims, Kristin E. Burnum-Johnson, Young-Mo Kim, Jennifer E. Kyle, Melissa M. Matzke, Anil K. Shukla, Rosalie K. Chu, Athena A. Schepmoes, Jon M. Jacobs, Ralph S. Baric, Bobbie-Jo Webb-Robertson, Richard D. Smith, Thomas O. Metz
Publié 2016

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

par Maria L. Agostini, Erica L. Andres, Amy C. Sims, Rachel L. Graham, Timothy P. Sheahan, Xiaotao Lu, Everett Clinton Smith, James Brett Case, Joy Y. Feng, Robert Jordan, Adrian S. Ray, Tomas Cihlar, Dustin Siegel, Richard L. Mackman, Michael O. Clarke, Ralph S. Baric, Mark R. Denison
Publié 2018

Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV

par Timothy P. Sheahan, Amy C. Sims, Sarah R. Leist, Alexandra Schäfer, John Won, Ariane J. Brown, Stephanie A. Montgomery, Alison Hogg, Darius Babusis, Michael O. Clarke, Jamie E. Spahn, Laura Bauer, Scott Sellers, Danielle Porter, Joy Y. Feng, Tomas Cihlar, Robert Jordan, Mark R. Denison, Ralph S. Baric
Publié 2020

Pathogenic Influenza Viruses and Coronaviruses Utilize Similar and Contrasting Approaches To Control Interferon-Stimulated Gene Responses

par Vineet D. Menachery, Amie J. Eisfeld, Alexandra Schäfer, Laurence Josset, Amy C. Sims, Sean Proll, Shufang Fan, Chengjun Li, Gabriele Neumann, Susan C. Tilton, Jean Chang, Lisa E. Gralinski, Casey Long, Richard Green, Christopher M. Williams, Jeffrey Weiss, Melissa M. Matzke, Bobbie-Jo Webb-Robertson, Athena A. Schepmoes, Anil K. Shukla, Thomas O. Metz, Richard D. Smith, Katrina M. Waters, Michael G. Katze, Yoshihiro Kawaoka, Ralph S. Baric
Publié 2014