ABHD11 maintains 2-oxoglutarate metabolism by preserving functional lipoylation of the 2-oxoglutarate dehydrogenase complex

por Peter S. J. Bailey, Brian M. Ortmann, Anthony W. Martinelli, Jack W. Houghton, Ana S. H. Costa, Stephen P. Burr, Robin Antrobus, Christian Frezza, James A. Nathan
Publicado 2020

Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis

por John S. O’ Neill, Nathaniel P. Hoyle, J. Brian Robertson, Rachel S. Edgar, Andrew D. Beale, Sew Y. Peak-Chew, Jason Day, Ana S. H. Costa, Christian Frezza, Helen C. Causton
Publicado 2020

Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis

por Clément Bodineau, Mercedes Tomé, Sarah Courtois, Ana S. H. Costa, Marco Sciacovelli, Benoit Rousseau, Elodie Richard, Pierre Vacher, Carlos Parejo-Pérez, Emilie Bessede, Christine Varon, Pierre Soubeyran, Christian Frezza, Piedad del Socorro Murdoch, Victor H. Villar, Raúl V. Durán
Publicado 2021

Long-term increased carnitine palmitoyltransferase 1A expression in ventromedial hypotalamus causes hyperphagia and alters the hypothalamic lipidomic profile.

por Paula Mera, Joan Francesc Mir, Gemma Fabriàs, Josefina Casas, Ana S H Costa, Maria Ida Malandrino, José-Antonio Fernández-López, Xavier Remesar, Su Gao, Shigeru Chohnan, Maria Sol Rodríguez-Peña, Harald Petry, Guillermina Asins, Fausto G Hegardt, Laura Herrero, Dolors Serra
Publicado 2014

Cancer associated fibroblast FAK regulates malignant cell metabolism

por Fevzi Demircioglu, Jun Wang, Juliana Candido, Ana S. H. Costa, Pedro Casado, Beatriz de Luxan Delgado, Louise E. Reynolds, Jesus Gomez-Escudero, Emma Newport, Vinothini Rajeeve, Ann-Marie Baker, Marina Roy-Luzarraga, Trevor A. Graham, Julie Foster, Yu Wang, James J. Campbell, Rajinder Singh, Penglie Zhang, Thomas J. Schall, Frances R. Balkwill, Jane Sosabowski, Pedro R. Cutillas, Christian Frezza, Patricia Sancho, Kairbaan Hodivala-Dilke
Publicado 2020