eIF2B as a Target for Viral Evasion of PKR-Mediated Translation Inhibition

por Jennifer Deborah Wuerth, Matthias Habjan, Markus Kainulainen, Besim Berisha, Damien Bertheloot, Giulio Superti-Furga, Andreas Pichlmair, Friedemann Weber
Publicado 2020

Genotoxic stress in constitutive trisomies induces autophagy and the innate immune response via the cGAS-STING pathway

por Maria Krivega, Clara M. Stiefel, Sahar Karbassi, Line L. Andersen, Narendra K. Chunduri, Neysan Donnelly, Andreas Pichlmair, Zuzana Storchová
Publicado 2021

Sequestration by IFIT1 impairs translation of 2'O-unmethylated capped RNA.

por Matthias Habjan, Philipp Hubel, Livia Lacerda, Christian Benda, Cathleen Holze, Christian H Eberl, Angelika Mann, Eveline Kindler, Cristina Gil-Cruz, John Ziebuhr, Volker Thiel, Andreas Pichlmair
Publicado 2013

NUDT2 initiates viral RNA degradation by removal of 5′-phosphates

por Beatrice T. Laudenbach, Karsten Krey, Quirin Emslander, Line Lykke Andersen, Alexander Reim, Pietro Scaturro, Sarah Mundigl, Christopher Dächert, Katrin Manske, Markus Moser, Janos Ludwig, Dirk Wohlleber, Andrea Kröger, Marco Binder, Andreas Pichlmair
Publicado 2021

The Zinc Finger Antiviral Protein ZAP Restricts Human Cytomegalovirus and Selectively Binds and Destabilizes Viral <i>UL4</i> / <i>UL5</i> Transcripts

por Ana Cristina Gonzalez-Perez, Markus Stempel, Emanuel Wyler, Christian Urban, Antonio Piras, Thomas Hennig, Sabina Ganskih, Yuanjie Wei, Albert Heim, Markus Landthaler, Andreas Pichlmair, Lars Dölken, Mathias Munschauer, Florian Erhard, Melanie M. Brinkmann
Publicado 2021

Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing

por Sepideh Sadegh, Julian Matschinske, David B. Blumenthal, Gihanna Galindez, Tim Kacprowski, Markus List, Reza Nasirigerdeh, Mhaned Oubounyt, Andreas Pichlmair, Tim Daniel Rose, Marisol Salgado-Albarrán, Julian Späth, Alexey Stukalov, Nina K. Wenke, Kevin Yuan, Josch K. Pauling, Jan Baumbach
Publicado 2020

Cross-species analysis of viral nucleic acid interacting proteins identifies TAOKs as innate immune regulators

por Friederike L. Pennemann, Assel Mussabekova, Christian Urban, Alexey Stukalov, Line Lykke Andersen, Vincent Grass, Teresa Maria Lavacca, Cathleen Holze, Lila Oubraham, Yasmine Benamrouche, Enrico Girardi, Rasha E. Boulos, Rune Hartmann, Giulio Superti-Furga, Matthias Habjan, Jean-Luc Imler, Carine Meignin, Andreas Pichlmair
Publicado 2021

Human cytomegalovirus-induced host protein citrullination is crucial for viral replication

por Gloria Griffante, Francesca Gugliesi, Selina Pasquero, Valentina Dell’Oste, Matteo Biolatti, Ari J. Salinger, Santanu Mondal, Paul R. Thompson, Eranthie Weerapana, Robert J. Lebbink, Jasper A. Soppe, Thomas Stamminger, Virginie Girault, Andreas Pichlmair, Gábor Oroszlán, Donald M. Coen, Marco De Andrea, Santo Landolfo
Publicado 2021

Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’

por David S. Fischer, Meshal Ansari, Karolin I. Wagner, Sebastian Jarosch, Yiqi Huang, Christoph H. Mayr, Maximilian Strunz, Niklas J. Lang, Elvira D’Ippolito, Monika Hammel, Laura Mateyka, Simone Weber, Lisa S. Wolff, Klaus Witter, Isis E. Fernandez, Gabriela Leuschner, Katrin Milger, Marion Frankenberger, Lorenz Nowak, Katharina Heinig-Menhard, Ina Koch, Mircea G. Stoleriu, Anne Hilgendorff, Jürgen Behr, Andreas Pichlmair, Benjamin Schubert, Fabian J. Theis, Dirk H. Busch, Herbert B. Schiller, Kilian Schober
Publicado 2021