Phosphorylation of 4E-BP1 in the mammalian brain is not altered by LRRK2 expression or pathogenic mutations.

por Alzbeta Trancikova, Adamantios Mamais, Philip J Webber, Klodjan Stafa, Elpida Tsika, Liliane Glauser, Andrew B West, Rina Bandopadhyay, Darren J Moore
Publicado 2012

Inhibition of LRRK2 kinase activity promotes anterograde axonal transport and presynaptic targeting of α-synuclein

por Charlotte F. Brzozowski, Baraa A. Hijaz, Vijay Singh, Nolwazi Z. Gcwensa, Kaela Kelly, Edward S. Boyden, Andrew B. West, Deblina Sarkar, Laura A. Volpicelli-Daley
Publicado 2021

LRRK2 levels in immune cells are increased in Parkinson’s disease

por D. A. Cook, G. T. Kannarkat, A. F. Cintron, Laura M. Butkovich, Kyle B. Fraser, J. Chang, N. Grigoryan, S. A. Factor, Andrew B. West, J. M. Boss, M. G. Tansey
Publicado 2017

Sex-based differences in the activation of peripheral blood monocytes in early Parkinson disease

por Samantha M. Carlisle, Hongwei Qin, R. Curtis Hendrickson, Jordana E. Muwanguzi, Elliot J. Lefkowitz, Richard E. Kennedy, Zhaoqi Yan, Talene A. Yacoubian, Etty N. Benveniste, Andrew B. West, Ashley S. Harms, David G. Standaert
Publicado 2021