Cholesterol metabolism drives regulatory B cell IL-10 through provision of geranylgeranyl pyrophosphate

por Jack A. Bibby, Harriet A. Purvis, Thomas Hayday, Anita Chandra, Klaus Okkenhaug, Sofia Rosenzweig, Ivona Aksentijevich, Michael Wood, Helen J. Lachmann, Claudia Kemper, Andrew P. Cope, Esperanza Perucha
Publicado 2020

3D Bayesian cluster analysis of super-resolution data reveals LAT recruitment to the T cell synapse

por Juliette Griffié, Leigh Shlomovich, David J. Williamson, Michael Shannon, Jesse Aaron, Satya Khuon, Garth L. Burn, Lies Boelen, Ruby Peters, Andrew P. Cope, Edward A. K. Cohen, Patrick Rubin-Delanchy, Dylan M. Owen
Publicado 2017

Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking.

por Ian C Scott, Seth D Seegobin, Sophia Steer, Rachael Tan, Paola Forabosco, Anne Hinks, Stephen Eyre, Ann W Morgan, Anthony G Wilson, Lynne J Hocking, Paul Wordsworth, Anne Barton, Jane Worthington, Andrew P Cope, Cathryn M Lewis
Publicado 2013

The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells

por Esperanza Perucha, Rossella Melchiotti, Jack A Bibby, Wing Wu, Klaus Stensgaard Frederiksen, Ceri A. Roberts, Zoe Hall, Gaelle LeFriec, Kevin A. Robertson, Paul Lavender, Jens Gammeltoft Gerwien, Leonie S. Taams, Julian L. Griffin, Emanuele de Rinaldis, Lisa G. M. van Baarsen, Claudia Kemper, Peter Ghazal, Andrew P. Cope
Publicado 2019