Host-directed therapy in foals can enhance functional innate immunity and reduce severity of Rhodococcus equi pneumonia

por Angela I. Bordin, Noah D. Cohen, Steve Giguère, Jocelyne M. Bray, Londa J. Berghaus, Brenton Scott, Rena Johnson, Magnus Hook
Publicado 2021

The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferon by engaging cytosolic DNA sensing in macrophages.

por Krystal J Vail, Bibiana Petri da Silveira, Samantha L Bell, Noah D Cohen, Angela I Bordin, Kristin L Patrick, Robert O Watson
Publicado 2021

Differences in the genome, methylome, and transcriptome do not differentiate isolates of Streptococcus equi subsp. equi from horses with acute clinical signs from isolates of inapp...

por Ellen Ruth A Morris, Ashley G Boyle, Miia Riihimäki, Anna Aspán, Eman Anis, Andrew E Hillhouse, Ivan Ivanov, Angela I Bordin, John Pringle, Noah D Cohen
Publicado 2021

Safe and effective aerosolization of in vitro transcribed mRNA to the respiratory tract epithelium of horses without a transfection agent

por Rebecca M. Legere, Noah D. Cohen, Cristina Poveda, Jocelyne M. Bray, Rola Barhoumi, Joseph A. Szule, Andrés de la Concha-Bermejillo, Angela I. Bordin, Jeroen Pollet
Publicado 2021

Antibody activities in hyperimmune plasma against the Rhodococcus equi virulence -associated protein A or poly-N-acetyl glucosamine are associated with protection of foals against...

por Susanne K Kahn, Colette Cywes-Bentley, Glenn P Blodgett, Nathan M Canaday, Carly E Turner-Garcia, Mariana Vinacur, Sophia C Cortez-Ramirez, Patrick J Sutter, Sarah C Meyer, Angela I Bordin, Daniel R Vlock, Gerald B Pier, Noah D Cohen
Publicado 2021