Full-length transcript characterization of SF3B1 mutation in chronic lymphocytic leukemia reveals downregulation of retained introns

par Alison D. Tang, Cameron M. Soulette, Marijke J. van Baren, Kevyn Hart, Eva Hrabeta-Robinson, Catherine J. Wu, Angela N. Brooks
Publié 2020

eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants.

par Alexis M Thornton, Lishan Fang, April Lo, Maria McSharry, David Haan, Casey O'Brien, Alice H Berger, Marios Giannakis, Angela N Brooks
Publié 2021

Inflammation drives alternative first exon usage to regulate immune genes including a novel iron-regulated isoform of Aim2

par Elektra K Robinson, Pratibha Jagannatha, Sergio Covarrubias, Matthew Cattle, Valeriya Smaliy, Rojin Safavi, Barbara Shapleigh, Robin Abu-Shumays, Miten Jain, Suzanne M Cloonan, Mark Akeson, Angela N Brooks, Susan Carpenter
Publié 2021

Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma

par Hector H. Huang, Ian D. Ferguson, Alexis M. Thornton, Prabhakar Bastola, Christine Lam, Yu-Hsiu T. Lin, Priya Choudhry, Margarette C. Mariano, Makeba D. Marcoulis, Chin Fen Teo, Julia Malato, Paul J. Phojanakong, Thomas G. Martin, Jeffrey L. Wolf, Sandy W. Wong, Nina Shah, Byron Hann, Angela N. Brooks, Arun P. Wiita
Publié 2020