Crystal structures of the mitochondrial deacylase Sirtuin 4 reveal isoform-specific acyl recognition and regulation features

par Martin Pannek, Zeljko Simic, Matthew Fuszard, Marat Meleshin, Dante Rotili, Antonello Mai, Mike Schutkowski, Clemens Steegborn
Publié 2017

Class II HDAC inhibition hampers hepatic stellate cell activation by induction of microRNA-29.

par Inge Mannaerts, Nathalie Eysackers, Oscar O Onyema, Katrien Van Beneden, Sergio Valente, Antonello Mai, Margarete Odenthal, Leo A van Grunsven
Publié 2013

Intergenerational inheritance of high fat diet-induced cardiac lipotoxicity in Drosophila

par Maria Clara Guida, Ryan Tyge Birse, Alessandra Dall’Agnese, Paula Coutinho Toto, Soda Balla Diop, Antonello Mai, Peter D. Adams, Pier Lorenzo Puri, Rolf Bodmer
Publié 2019

Sirtinol treatment reduces inflammation in human dermal microvascular endothelial cells.

par Angela Orecchia, Claudia Scarponi, Francesca Di Felice, Elisa Cesarini, Simona Avitabile, Antonello Mai, Maria Luisa Mauro, Valentina Sirri, Giovanna Zambruno, Cristina Albanesi, Giorgio Camilloni, Cristina M Failla
Publié 2011

HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal

par Lucia Rossi, Cecilia Battistelli, Valeria de Turris, Valeria Noce, Clemens Zwergel, Sergio Valente, Alessandra Moioli, Andrea Manzione, Marco Palladino, Veronica Bordoni, Alessandro Domenici, Paolo Menè, Antonello Mai, Marco Tripodi, Raffaele Strippoli
Publié 2018

Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

par Jay H. Kalin, Muzhou Wu, Andrea V. Gomez, Yun Song, Jayanta Das, Dawn Hayward, Nkosi Adejola, Mingxuan Wu, Izabela Panova, Hye Jin Chung, Edward Kim, Holly J. Roberts, Justin M. Roberts, Polina Prusevich, Jeliazko R. Jeliazkov, Shourya S. Roy Burman, Louise Fairall, Charles Milano, Abdulkerim Eroglu, Charlotte M. Proby, Albena T. Dinkova-Kostova, Wayne W. Hancock, Jeffrey J. Gray, James E. Bradner, Sergio Valente, Antonello Mai, Nicole M. Anders, Michelle A. Rudek, Yong Hu, Byungwoo Ryu, John W. R. Schwabe, Andrea Mattevi, Rhoda M. Alani, Philip A. Cole
Publié 2018