U2 snRNA structure is influenced by SF3A and SF3B proteins but not by SF3B inhibitors.

por Veronica K Urabe, Meredith Stevers, Arun K Ghosh, Melissa S Jurica
Publicado 2021

Mechanism of Darunavir (DRV)’s High Genetic Barrier to HIV-1 Resistance: A Key V32I Substitution in Protease Rarely Occurs, but Once It Occurs, It Predisposes HIV-1 To Develop DRV...

por Manabu Aoki, Debananda Das, Hironori Hayashi, Hiromi Aoki-Ogata, Yuki Takamatsu, Arun K. Ghosh, Hiroaki Mitsuya
Publicado 2018

Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors

por Constantin Cretu, Patricia Gee, Xiang Liu, Anant Agrawal, Tuong-Vi Nguyen, Arun K. Ghosh, Andrew Cook, Melissa Jurica, Nicholas A. Larsen, Vladimir Pena
Publicado 2021

GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection

por Shin-ichiro Hattori, Nobuyo Higshi-Kuwata, Jakka Raghavaiah, Debananda Das, Haydar Bulut, David A. Davis, Yuki Takamatsu, Kouki Matsuda, Nobutoki Takamune, Naoki Kishimoto, Tadashi Okamura, Shogo Misumi, Robert Yarchoan, Kenji Maeda, Arun K. Ghosh, Hiroaki Mitsuya
Publicado 2020

A Mouse Model for <italic toggle="yes">Betacoronavirus</italic> Subgroup 2c Using a Bat Coronavirus Strain HKU5 Variant

por Sudhakar Agnihothram, Boyd L. Yount, Eric F. Donaldson, Jeremy Huynh, Vineet D. Menachery, Lisa E. Gralinski, Rachel L. Graham, Michelle M. Becker, Sakshi Tomar, Trevor D. Scobey, Heather L. Osswald, Alan Whitmore, Robin Gopal, Arun K. Ghosh, Andrew Mesecar, Maria Zambon, Mark Heise, Mark R. Denison, Ralph S. Baric
Publicado 2014

A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication

por Shin-ichiro Hattori, Nobuyo Higashi-Kuwata, Hironori Hayashi, Srinivasa Rao Allu, Jakka Raghavaiah, Haydar Bulut, Debananda Das, Brandon J. Anson, Emma K. Lendy, Yuki Takamatsu, Nobutoki Takamune, Naoki Kishimoto, Kazutaka Murayama, Kazuya Hasegawa, Mi Li, David A. Davis, Eiichi N. Kodama, Robert Yarchoan, Alexander Wlodawer, Shogo Misumi, Andrew D. Mesecar, Arun K. Ghosh, Hiroaki Mitsuya
Publicado 2021