USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth

par Maria E. Gierisch, Gloria Pedot, Franziska Walser, Laura A. Lopez-Garcia, Patricia Jaaks, Felix K. Niggli, Beat W. Schäfer
Publié 2019

Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity

par Gabriele Manzella, Leonie D. Schreck, Willemijn B. Breunis, Jan Molenaar, Hans Merks, Frederic G. Barr, Wenyue Sun, Michaela Römmele, Luduo Zhang, Joelle Tchinda, Quy A. Ngo, Peter Bode, Olivier Delattre, Didier Surdez, Bharat Rekhi, Felix K. Niggli, Beat W. Schäfer, Marco Wachtel
Publié 2020

BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma

par Dominik Laubscher, Berkley E. Gryder, Benjamin D. Sunkel, Thorkell Andresson, Marco Wachtel, Sudipto Das, Bernd Roschitzki, Witold Wolski, Xiaoli S. Wu, Hsien-Chao Chou, Young K. Song, Chaoyu Wang, Jun S. Wei, Meng Wang, Xinyu Wen, Quy Ai Ngo, Joana G. Marques, Christopher R. Vakoc, Beat W. Schäfer, Benjamin Z. Stanton, Javed Khan
Publié 2021