A high-throughput cell-based assay pipeline for the preclinical development of bacterial DsbA inhibitors as antivirulence therapeutics

por Anthony D. Verderosa, Rabeb Dhouib, Yaoqin Hong, Taylah K. Anderson, Begoña Heras, Makrina Totsika
Publicado 2021

Comparative sequence, structure and redox analyses of Klebsiella pneumoniae DsbA show that anti-virulence target DsbA enzymes fall into distinct classes.

por Fabian Kurth, Kieran Rimmer, Lakshmanane Premkumar, Biswaranjan Mohanty, Wilko Duprez, Maria A Halili, Stephen R Shouldice, Begoña Heras, David P Fairlie, Martin J Scanlon, Jennifer L Martin
Publicado 2013

Molecular and Structural Characterization of a Novel <named-content content-type="genus-species">Escherichia coli</named-content> Interleukin Receptor Mimic Protein

por Danilo G. Moriel, Begoña Heras, Jason J. Paxman, Alvin W. Lo, Lendl Tan, Matthew J. Sullivan, Samantha J. Dando, Scott A. Beatson, Glen C. Ulett, Mark A. Schembri
Publicado 2016

A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance

por Emily J. Furlong, Alvin W. Lo, Fabian Kurth, Lakshmanane Premkumar, Makrina Totsika, Maud E. S. Achard, Maria A. Halili, Begoña Heras, Andrew E. Whitten, Hassanul G. Choudhury, Mark A. Schembri, Jennifer L. Martin
Publicado 2017

Author Correction: A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance

por Emily J. Furlong, Alvin W. Lo, Fabian Kurth, Lakshmanane Premkumar, Makrina Totsika, Maud E. S. Achard, Maria A. Halili, Begoña Heras, Andrew E. Whitten, Hassanul G. Choudhury, Mark A. Schembri, Jennifer L. Martin
Publicado 2019

Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules

por Jason J. Paxman, Alvin W. Lo, Matthew J. Sullivan, Santosh Panjikar, Michael Kuiper, Andrew E. Whitten, Geqing Wang, Chi-Hao Luan, Danilo G. Moriel, Lendl Tan, Kate M. Peters, Minh-Duy Phan, Christine L. Gee, Glen C. Ulett, Mark A. Schembri, Begoña Heras
Publicado 2019