Vaccines for human fungal diseases: close but still a long way to go

por Lorena V. N. Oliveira, Ruiying Wang, Charles A. Specht, Stuart M. Levitz
Publicado 2021

A Glycosylphosphatidylinositol Anchor Is Required for Membrane Localization but Dispensable for Cell Wall Association of Chitin Deacetylase 2 in <named-content content-type="genus-...

por Nicole M. Gilbert, Lorina G. Baker, Charles A. Specht, Jennifer K. Lodge
Publicado 2012

Robust Stimulation of Humoral and Cellular Immune Responses following Vaccination with Antigen-Loaded β-Glucan Particles

por Haibin Huang, Gary R. Ostroff, Chrono K. Lee, Charles A. Specht, Stuart M. Levitz
Publicado 2010

Induction of Protective Immunity to Cryptococcal Infection in Mice by a Heat-Killed, Chitosan-Deficient Strain of <named-content content-type="genus-species">Cryptococcus neoforman...

por Rajendra Upadhya, Woei C. Lam, Brian Maybruck, Charles A. Specht, Stuart M. Levitz, Jennifer K. Lodge
Publicado 2016

<named-content content-type="genus-species">Cryptococcus neoformans</named-content> Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis

por Rajendra Upadhya, Lorina G. Baker, Woei C. Lam, Charles A. Specht, Maureen J. Donlin, Jennifer K. Lodge
Publicado 2018

The Aminoalkylindole BML-190 Negatively Regulates Chitosan Synthesis via the Cyclic AMP/Protein Kinase A1 Pathway in <named-content content-type="genus-species">Cryptococcus neofor...

por Brian T. Maybruck, Woei C. Lam, Charles A. Specht, Ma. Xenia G. Ilagan, Maureen J. Donlin, Jennifer K. Lodge
Publicado 2019

Linkage Specificity and Role of Properdin in Activation of the Alternative Complement Pathway by Fungal Glycans

por Sarika Agarwal, Charles A. Specht, Haibin Huang, Gary R. Ostroff, Sanjay Ram, Peter A. Rice, Stuart M. Levitz
Publicado 2011

Lung eosinophils elicited during allergic and acute aspergillosis express RORγt and IL-23R but do not require IL-23 for IL-17 production.

por Bhawna Yadav, Charles A Specht, Chrono K Lee, Maria Pokrovskii, Jun R Huh, Dan R Littman, Stuart M Levitz
Publicado 2021

Chitosan Biosynthesis and Virulence in the Human Fungal Pathogen <named-content content-type="genus-species">Cryptococcus gattii</named-content>

por Woei C. Lam, Rajendra Upadhya, Charles A. Specht, Abigail E. Ragsdale, Camaron R. Hole, Stuart M. Levitz, Jennifer K. Lodge
Publicado 2019

Cross Talk between the Cell Wall Integrity and Cyclic AMP/Protein Kinase A Pathways in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>

por Maureen J. Donlin, Rajendra Upadhya, Kimberly J. Gerik, Woei Lam, Laura G. VanArendonk, Charles A. Specht, Neil K. Sharma, Jennifer K. Lodge
Publicado 2014

Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing <italic toggle="yes">Cryptococcus</italic> Alkaline Extracts

por Charles A. Specht, Chrono K. Lee, Haibin Huang, Donald J. Tipper, Zu T. Shen, Jennifer K. Lodge, John Leszyk, Gary R. Ostroff, Stuart M. Levitz
Publicado 2015

Vaccination with Recombinant <italic toggle="yes">Cryptococcus</italic> Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain an...

por Charles A. Specht, Chrono K. Lee, Haibin Huang, Maureen M. Hester, Jianhua Liu, Bridget A. Luckie, Melanie A. Torres Santana, Zeynep Mirza, Payam Khoshkenar, Ambily Abraham, Zu T. Shen, Jennifer K. Lodge, Ali Akalin, Jane Homan, Gary R. Ostroff, Stuart M. Levitz
Publicado 2017

Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression

por Patricia P. Yee, Yiju Wei, Soo-Yeon Kim, Tong Lu, Stephen Y. Chih, Cynthia Lawson, Miaolu Tang, Zhijun Liu, Benjamin Anderson, Krishnamoorthy Thamburaj, Megan M. Young, Dawit G. Aregawi, Michael J. Glantz, Brad E. Zacharia, Charles S. Specht, Hong-Gang Wang, Wei Li
Publicado 2020