Interleukin-21 receptor signalling is important for innate immune protection against HSV-2 infections.

por Sine K Kratholm, Marie B Iversen, Line Reinert, Simon K Jensen, Marianne Hokland, Thomas Andersen, Andrew Rankin, Deborah Young, Sebastian Frische, Søren R Paludan, Christian K Holm
Publicado 2013

Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses

por Christian K. Holm, Stine H. Rahbek, Hans Henrik Gad, Rasmus O. Bak, Martin R. Jakobsen, Zhaozaho Jiang, Anne Louise Hansen, Simon K. Jensen, Chenglong Sun, Martin K. Thomsen, Anders Laustsen, Camilla G. Nielsen, Kasper Severinsen, Yingluo Xiong, Dara L. Burdette, Veit Hornung, Robert Jan Lebbink, Mogens Duch, Katherine A. Fitzgerald, Shervin Bahrami, Jakob Giehm Mikkelsen, Rune Hartmann, Søren R. Paludan
Publicado 2016

Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming

por David Olagnier, Aske M. Brandtoft, Camilla Gunderstofte, Nikolaj L. Villadsen, Christian Krapp, Anne L. Thielke, Anders Laustsen, Suraj Peri, Anne Louise Hansen, Lene Bonefeld, Jacob Thyrsted, Victor Bruun, Marie B. Iversen, Lin Lin, Virginia M. Artegoitia, Chenhe Su, Long Yang, Rongtuan Lin, Siddharth Balachandran, Yonglun Luo, Mette Nyegaard, Bernadette Marrero, Raphaela Goldbach-Mansky, Mona Motwani, Dylan G. Ryan, Katherine A. Fitzgerald, Luke A. O’Neill, Anne K. Hollensen, Christian K. Damgaard, Frank v. de Paoli, Hanne C. Bertram, Martin R. Jakobsen, Thomas B. Poulsen, Christian K. Holm
Publicado 2018

SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

por David Olagnier, Ensieh Farahani, Jacob Thyrsted, Julia Blay-Cadanet, Angela Herengt, Manja Idorn, Alon Hait, Bruno Hernaez, Alice Knudsen, Marie Beck Iversen, Mirjam Schilling, Sofie E. Jørgensen, Michelle Thomsen, Line S. Reinert, Michael Lappe, Huy-Dung Hoang, Victoria H. Gilchrist, Anne Louise Hansen, Rasmus Ottosen, Camilla G. Nielsen, Charlotte Møller, Demi van der Horst, Suraj Peri, Siddharth Balachandran, Jinrong Huang, Martin Jakobsen, Esben B. Svenningsen, Thomas B. Poulsen, Lydia Bartsch, Anne L. Thielke, Yonglun Luo, Tommy Alain, Jan Rehwinkel, Antonio Alcamí, John Hiscott, Trine H. Mogensen, Søren R. Paludan, Christian K. Holm
Publicado 2020