Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein–protein interactions

por Eline Sijbesma, Emira Visser, Kathrin Plitzko, Philipp Thiel, Lech-Gustav Milroy, Markus Kaiser, Luc Brunsveld, Christian Ottmann
Publicado 2020

Molecular basis for inhibition of adhesin-mediated bacterial-host interactions through a peptide-binding domain

por Shuaiqi Guo, Hossein Zahiri, Corey Stevens, Daniel C. Spaanderman, Lech-Gustav Milroy, Christian Ottmann, Luc Brunsveld, Ilja K. Voets, Peter L. Davies
Publicado 2021

Ultra-large chemical libraries for the discovery of high-affinity peptide binders

por Anthony J. Quartararo, Zachary P. Gates, Bente A. Somsen, Nina Hartrampf, Xiyun Ye, Arisa Shimada, Yasuhiro Kajihara, Christian Ottmann, Bradley L. Pentelute
Publicado 2020

Intermolecular channels direct crystal orientation in mineralized collagen

por YiFei Xu, Fabio Nudelman, E. Deniz Eren, Maarten J. M. Wirix, Bram Cantaert, Wouter H. Nijhuis, Daniel Hermida-Merino, Giuseppe Portale, Paul H. H. Bomans, Christian Ottmann, Heiner Friedrich, Wim Bras, Anat Akiva, Joseph P. R. O. Orgel, Fiona C. Meldrum, Nico Sommerdijk
Publicado 2020