A scalable Drosophila assay for clinical interpretation of human PTEN variants in suppression of PI3K/AKT induced cellular proliferation.

por Payel Ganguly, Landiso Madonsela, Jesse T Chao, Christopher J R Loewen, Timothy P O'Connor, Esther M Verheyen, Douglas W Allan
Publicado 2021

A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria.

por Sujoy Lahiri, Jesse T Chao, Shabnam Tavassoli, Andrew K O Wong, Vineet Choudhary, Barry P Young, Christopher J R Loewen, William A Prinz
Publicado 2014

Viral proteins as a potential driver of histone depletion in dinoflagellates

por Nicholas A. T. Irwin, Benjamin J. E. Martin, Barry P. Young, Martin J. G. Browne, Andrew Flaus, Christopher J. R. Loewen, Patrick J. Keeling, LeAnn J. Howe
Publicado 2018

Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction

por Kathryn L. Post, Manuel Belmadani, Payel Ganguly, Fabian Meili, Riki Dingwall, Troy A. McDiarmid, Warren M. Meyers, Caitlin Herrington, Barry P. Young, Daniel B. Callaghan, Sanja Rogic, Matthew Edwards, Ana Niciforovic, Alessandro Cau, Catharine H. Rankin, Timothy P. O’Connor, Shernaz X. Bamji, Christopher J. R. Loewen, Douglas W. Allan, Paul Pavlidis, Kurt Haas
Publicado 2020