A TFEB nuclear export signal integrates amino acid supply and glucose availability

par Linxin Li, Hans J. Friedrichsen, Sarah Andrews, Sarah Picaud, Laurent Volpon, Kaochin Ngeow, Georgina Berridge, Roman Fischer, Katherine L. B. Borden, Panagis Filippakopoulos, Colin R. Goding
Publié 2018

Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells

par Rasmus Freter, Paola Falletta, Omid Omrani, Mahdi Rasa, Katharine Herbert, Francesco Annunziata, Alberto Minetti, Anna Krepelova, Lisa Adam, Sandra Käppel, Tina Rüdiger, Zhao-Qi Wang, Colin R. Goding, Francesco Neri
Publié 2021

Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads

par Shuyang Chen, Changpeng Han, Xiao Miao, Xin Li, Chengqian Yin, Junrong Zou, Min Liu, Shanshan Li, Lukasz Stawski, Bo Zhu, Qiong Shi, Zhi-Xiang Xu, Chunying Li, Colin R. Goding, Jun Zhou, Rutao Cui
Publié 2019

Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma

par Jose Mario Gonzalez-Meljem, Scott Haston, Gabriela Carreno, John R. Apps, Sara Pozzi, Christina Stache, Grace Kaushal, Alex Virasami, Leonidas Panousopoulos, Seyedeh Neda Mousavy-Gharavy, Ana Guerrero, Mamunur Rashid, Nital Jani, Colin R. Goding, Thomas S. Jacques, David J. Adams, Jesus Gil, Cynthia L. Andoniadou, Juan Pedro Martinez-Barbera
Publié 2017

BRN2 is a non-canonical melanoma tumor-suppressor

par Michael Hamm, Pierre Sohier, Valérie Petit, Jérémy H. Raymond, Véronique Delmas, Madeleine Le Coz, Franck Gesbert, Colin Kenny, Zackie Aktary, Marie Pouteaux, Florian Rambow, Alain Sarasin, Nisamanee Charoenchon, Alfonso Bellacosa, Luis Sanchez-del-Campo, Laura Mosteo, Martin Lauss, Dies Meijer, Eirikur Steingrimsson, Göran B. Jönsson, Robert A. Cornell, Irwin Davidson, Colin R. Goding, Lionel Larue
Publié 2021

Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers

par Eva Pérez-Guijarro, Panagiotis Karras, Metehan Cifdaloz, Raúl Martínez-Herranz, Estela Cañón, Osvaldo Graña, Celia Horcajada-Reales, Direna Alonso-Curbelo, Tonantzin G. Calvo, Gonzalo Gómez-López, Nicolas Bellora, Erica Riveiro-Falkenbach, Pablo L. Ortiz-Romero, José L. Rodríguez-Peralto, Lorena Maestre, Giovanna Roncador, Juan C. de Agustín Asensio, Colin R. Goding, Eduardo Eyras, Diego Megías, Raúl Méndez, María S. Soengas
Publié 2016

The protective role of DOT1L in UV-induced melanomagenesis

par Bo Zhu, Shuyang Chen, Hongshen Wang, Chengqian Yin, Changpeng Han, Cong Peng, Zhaoqian Liu, Lixin Wan, Xiaoyang Zhang, Jie Zhang, Christine G. Lian, Peilin Ma, Zhi-xiang Xu, Sharon Prince, Tao Wang, Xiumei Gao, Yujiang Shi, Dali Liu, Min Liu, Wenyi Wei, Zhi Wei, Jingxuan Pan, Yongjun Wang, Zhenyu Xuan, Jay Hess, Nicholas K. Hayward, Colin R. Goding, Xiang Chen, Jun Zhou, Rutao Cui
Publié 2018

Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5 −/− mice

par Yan Li, Roberto Tinoco, Lisa Elmén, Igor Segota, Yibo Xian, Yu Fujita, Avinash Sahu, Raphy Zarecki, Kerrie Marie, Yongmei Feng, Ali Khateb, Dennie T. Frederick, Shiri K. Ashkenazi, Hyungsoo Kim, Eva Guijarro Perez, Chi-Ping Day, Rafael S. Segura Muñoz, Robert Schmaltz, Shibu Yooseph, Miguel A. Tam, Tongwu Zhang, Emily Avitan-Hersh, Lihi Tzur, Shoshana Roizman, Ilanit Boyango, Gil Bar-Sela, Amir Orian, Randal J. Kaufman, Marcus Bosenberg, Colin R. Goding, Bas Baaten, Mitchell P. Levesque, Reinhard Dummer, Kevin Brown, Glenn Merlino, Eytan Ruppin, Keith Flaherty, Amanda Ramer-Tait, Tao Long, Scott N. Peterson, Linda M. Bradley, Ze’ev A. Ronai
Publié 2019