Mitotic Errors Promote Genomic Instability and Leukemia in a Novel Mouse Model of Fanconi Anemia

por Donna M. Edwards, Donna M. Edwards, Donna M. Edwards, Dana K. Mitchell, Dana K. Mitchell, Zahi Abdul-Sater, Zahi Abdul-Sater, Ka-Kui Chan, Ka-Kui Chan, Zejin Sun, Aditya Sheth, Aditya Sheth, Ying He, Li Jiang, Jin Yuan, Richa Sharma, Richa Sharma, Magdalena Czader, Pei-Ju Chin, Yie Liu, Guillermo de Cárcer, Grzegorz Nalepa, Grzegorz Nalepa, Grzegorz Nalepa, Grzegorz Nalepa, Hal E. Broxmeyer, D. Wade Clapp, D. Wade Clapp, D. Wade Clapp, D. Wade Clapp, Elizabeth A. Sierra Potchanant, Elizabeth A. Sierra Potchanant
Publicado 2021

Inhibition of p21 activated kinase (PAK) reduces airway responsiveness in vivo and in vitro in murine and human airways.

por Wyn C Hoover, Wenwu Zhang, Zhidong Xue, Huanling Gao, Jonathan Chernoff, D Wade Clapp, Susan J Gunst, Robert S Tepper
Publicado 2012

Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK.

por Long-Sheng Chang, Janet L Oblinger, Abbi E Smith, Marc Ferrer, Steven P Angus, Eric Hawley, Alejandra M Petrilli, Roberta L Beauchamp, Lars Björn Riecken, Serkan Erdin, Ming Poi, Jie Huang, Waylan K Bessler, Xiaohu Zhang, Rajarshi Guha, Craig Thomas, Sarah S Burns, Thomas S K Gilbert, Li Jiang, Xiaohong Li, Qingbo Lu, Jin Yuan, Yongzheng He, Shelley A H Dixon, Andrea Masters, David R Jones, Charles W Yates, Stephen J Haggarty, Salvatore La Rosa, D Bradley Welling, Anat O Stemmer-Rachamimov, Scott R Plotkin, James F Gusella, Justin Guinney, Helen Morrison, Vijaya Ramesh, Cristina Fernandez-Valle, Gary L Johnson, Jaishri O Blakeley, D Wade Clapp, Synodos for NF2 Consortium
Publicado 2021