Modeling genome-wide enzyme evolution predicts strong epistasis underlying catalytic turnover rates

por David Heckmann, Daniel C. Zielinski, Bernhard O. Palsson
Publicado 2018

The quantitative metabolome is shaped by abiotic constraints

por Amir Akbari, James T. Yurkovich, Daniel C. Zielinski, Bernhard O. Palsson
Publicado 2021

Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models

por David Heckmann, Colton J. Lloyd, Nathan Mih, Yuanchi Ha, Daniel C. Zielinski, Zachary B. Haiman, Abdelmoneim Amer Desouki, Martin J. Lercher, Bernhard O. Palsson
Publicado 2018