Modeling genome-wide enzyme evolution predicts strong epistasis underlying catalytic turnover rates

par David Heckmann, Daniel C. Zielinski, Bernhard O. Palsson
Publié 2018

The quantitative metabolome is shaped by abiotic constraints

par Amir Akbari, James T. Yurkovich, Daniel C. Zielinski, Bernhard O. Palsson
Publié 2021

Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models

par David Heckmann, Colton J. Lloyd, Nathan Mih, Yuanchi Ha, Daniel C. Zielinski, Zachary B. Haiman, Abdelmoneim Amer Desouki, Martin J. Lercher, Bernhard O. Palsson
Publié 2018