Natural variants in SARS-CoV-2 Spike protein pinpoint structural and functional hotspots with implications for prophylaxis and therapeutic strategies

par Suman Pokhrel, Benjamin R. Kraemer, Scott Burkholz, Daria Mochly-Rosen
Publié 2021

Increased elastase sensitivity and decreased intramolecular interactions in the more transmissible 501Y.V1 and 501Y.V2 SARS-CoV-2 variants' spike protein-an in silico analysis.

par Suman Pokhrel, Benjamin R Kraemer, Lucia Lee, Kate Samardzic, Daria Mochly-Rosen
Publié 2021

Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator

par Sunhee Hwang, Karen Mruk, Simin Rahighi, Andrew G. Raub, Che-Hong Chen, Lisa E. Dorn, Naoki Horikoshi, Soichi Wakatsuki, James K. Chen, Daria Mochly-Rosen
Publié 2018

VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington’s disease

par Xing Guo, XiaoYan Sun, Di Hu, Ya-Juan Wang, Hisashi Fujioka, Rajan Vyas, Sudha Chakrapani, Amit Umesh Joshi, Yu Luo, Daria Mochly-Rosen, Xin Qi
Publié 2016

Transcriptome analysis and prognosis of ALDH isoforms in human cancer

par Peter Mu-Hsin Chang, Che-Hong Chen, Chi-Chun Yeh, Hsueh-Ju Lu, Tze-Tze Liu, Ming-Huang Chen, Chun-Yu Liu, Alexander T. H. Wu, Muh-Hwa Yang, Shyh-Kuan Tai, Daria Mochly-Rosen, Chi-Ying F. Huang
Publié 2018

A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats

par Julio C. B. Ferreira, Juliane C. Campos, Nir Qvit, Xin Qi, Luiz H. M. Bozi, Luiz R. G. Bechara, Vanessa M. Lima, Bruno B. Queliconi, Marie-Helene Disatnik, Paulo M. M. Dourado, Alicia J. Kowaltowski, Daria Mochly-Rosen
Publié 2019