Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization

por Serif Senturk, Nitin H. Shirole, Dawid G. Nowak, Vincenzo Corbo, Debjani Pal, Alexander Vaughan, David A. Tuveson, Lloyd C. Trotman, Justin B. Kinney, Raffaella Sordella
Publicado 2017

RhoC interacts with integrin α5β1 and enhances its trafficking in migrating pancreatic carcinoma cells.

por Ningfeng Fiona Li, Emilios Gemenetzidis, Francis J Marshall, Derek Davies, Yongwei Yu, Kristopher Frese, Fieke E M Froeling, Adam K Woolf, Roger M Feakins, Yoshiki Naito, Christine Iacobuzio-Donahue, David A Tuveson, Ian R Hart, Hemant M Kocher
Publicado 2013

Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade

por Sebastian R. Nielsen, Jan E. Strøbech, Edward R. Horton, Rene Jackstadt, Anu Laitala, Marina C. Bravo, Giorgia Maltese, Adina R. D. Jensen, Raphael Reuten, Maria Rafaeva, Saadia A. Karim, Chang-Il Hwang, Luis Arnes, David A. Tuveson, Owen J. Sansom, Jennifer P. Morton, Janine T. Erler
Publicado 2021