Inhibition of calpain blocks the phagosomal escape of Listeria monocytogenes.

par Gloria Lopez-Castejon, David Corbett, Marie Goldrick, Ian S Roberts, David Brough
Publié 2012

Redefining the ancestral origins of the interleukin-1 superfamily

par Jack Rivers-Auty, Michael J. D. Daniels, Isaac Colliver, David L. Robertson, David Brough
Publié 2018

Salmonella typhimurium-induced IL-1 release from primary human monocytes requires NLRP3 and can occur in the absence of pyroptosis

par Catherine E. Diamond, Keith Weng Kit Leong, Maurizio Vacca, Jack Rivers-Auty, David Brough, Alessandra Mortellaro
Publié 2017

A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation

par Sohaib Nizami, Val Millar, Kanisa Arunasalam, Tryfon Zarganes-Tzitzikas, David Brough, Gary Tresadern, Paul E. Brennan, John B. Davis, Daniel Ebner, Elena Di Daniel
Publié 2021

Evidence That a TRPA1-Mediated Murine Model of Temporomandibular Joint Pain Involves NLRP3 Inflammasome Activation

par Xenia Kodji, Zizheng Kee, Robyn McKenna, Joao de Sousa Valente, Harriet Ravenscroft, Hayley McMillan, John Gamble, Yvonne Dombrowski, Paul Moynagh, David Brough, Fionnuala T. Lundy, Susan D. Brain, Ikhlas A. El Karim
Publié 2021

Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models

par Michael J. D. Daniels, Jack Rivers-Auty, Tom Schilling, Nicholas G. Spencer, William Watremez, Victoria Fasolino, Sophie J. Booth, Claire S. White, Alex G. Baldwin, Sally Freeman, Raymond Wong, Clare Latta, Shi Yu, Joshua Jackson, Nicolas Fischer, Violette Koziel, Thierry Pillot, James Bagnall, Stuart M. Allan, Pawel Paszek, James Galea, Michael K. Harte, Claudia Eder, Catherine B. Lawrence, David Brough
Publié 2016