Identification and Evaluation of Improved 4′-<italic toggle="yes">O</italic>-(Alkyl) 4,5-Disubstituted 2-Deoxystreptamines as Next-Generation Aminoglycoside Antibiotics

por Stefan Duscha, Heithem Boukari, Dimitri Shcherbakov, Sumantha Salian, Sandrina Silva, Ann Kendall, Takayuki Kato, Rashid Akbergenov, Deborah Perez-Fernandez, Bruno Bernet, Swapna Vaddi, Pia Thommes, Jochen Schacht, David Crich, Andrea Vasella, Erik C. Böttger
Publicado 2014

Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis

por Katja Becker, Sha Cao, Anna Nilsson, Maria Erlandsson, Sven-Kevin Hotop, Janis Kuka, Jon Hansen, Klara Haldimann, Solveiga Grinberga, Talia Berruga-Fernández, Douglas L. Huseby, Reza Shariatgorji, Evelina Lindmark, Björn Platzack, Erik C. Böttger, David Crich, Lena E. Friberg, Carina Vingsbo Lundberg, Diarmaid Hughes, Mark Brönstrup, Per E. Andrén, Edgars Liepinsh, Sven N. Hobbie
Publicado 2021