Dynamic modelling of the PI3K/MTOR signalling network uncovers biphasic dependence of mTORC1 activity on the mTORC2 subunit SIN1.

par Milad Ghomlaghi, Guang Yang, Sung-Young Shin, David E James, Lan K Nguyen
Publié 2021

Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training

par Maximilian Kleinert, Benjamin L. Parker, Thomas E. Jensen, Steffen H. Raun, Phung Pham, Xiuqing Han, David E. James, Erik A. Richter, Lykke Sylow
Publié 2018

Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy

par Mengbo Li, Benjamin L. Parker, Evangeline Pearson, Benjamin Hunter, Jacob Cao, Yen Chin Koay, Oneka Guneratne, David E. James, Jean Yang, Sean Lal, John F. O’Sullivan
Publié 2020

A hierarchical approach to removal of unwanted variation for large-scale metabolomics data

par Taiyun Kim, Owen Tang, Stephen T. Vernon, Katharine A. Kott, Yen Chin Koay, John Park, David E. James, Stuart M. Grieve, Terence P. Speed, Pengyi Yang, Gemma A. Figtree, John F. O’Sullivan, Jean Yee Hwa Yang
Publié 2021

Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival

par Marin E. Nelson, Sujoy Lahiri, Jenny D. Y. Chow, Frances L. Byrne, Stefan R. Hargett, David S. Breen, Ellen M. Olzomer, Lindsay E. Wu, Gregory J. Cooney, Nigel Turner, David E. James, Jill K. Slack-Davis, Carolin Lackner, Stephen H. Caldwell, Kyle L. Hoehn
Publié 2017

Correction: Corrigendum: 14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function

par Simone M. Schoenwaelder, Roxane Darbousset, Susan L. Cranmer, Hayley S. Ramshaw, Stephanie L. Orive, Sharelle Sturgeon, Yuping Yuan, Yu Yao, James R. Krycer, Joanna Woodcock, Jessica Maclean, Stuart Pitson, Zhaohua Zheng, Darren C. Henstridge, Dianne van der Wal, Elizabeth E. Gardiner, Michael C. Berndt, Robert K. Andrews, David E. James, Angel F. Lopez, Shaun P. Jackson
Publié 2017

14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function

par Simone M. Schoenwaelder, Roxane Darbousset, Susan L. Cranmer, Hayley S. Ramshaw, Stephanie L. Orive, Sharelle Sturgeon, Yuping Yuan, Yu Yao, James R. Krycer, Joanna Woodcock, Jessica Maclean, Stuart Pitson, Zhaohua Zheng, Darren C. Henstridge, Dianne van der Wal, Elizabeth E. Gardiner, Michael C. Berndt, Robert K. Andrews, David E. James, Angel F. Lopez, Shaun P. Jackson
Publié 2016

Global redox proteome and phosphoproteome analysis reveals redox switch in Akt

par Zhiduan Su, James G. Burchfield, Pengyi Yang, Sean J. Humphrey, Guang Yang, Deanne Francis, Sabina Yasmin, Sung-Young Shin, Dougall M. Norris, Alison L. Kearney, Miro A. Astore, Jonathan Scavuzzo, Kelsey H. Fisher-Wellman, Qiao-Ping Wang, Benjamin L. Parker, G. Gregory Neely, Fatemeh Vafaee, Joyce Chiu, Reichelle Yeo, Philip J. Hogg, Daniel J. Fazakerley, Lan K. Nguyen, Serdar Kuyucak, David E. James
Publié 2019