Gating of TonB-dependent transporters by substrate-specific forced remodelling

por Samuel J. Hickman, Rachael E. M. Cooper, Luca Bellucci, Emanuele Paci, David J. Brockwell
Publicado 2017

A force-activated trip switch triggers rapid dissociation of a colicin from its immunity protein.

por Oliver E Farrance, Eleanore Hann, Renata Kaminska, Nicholas G Housden, Sasha R Derrington, Colin Kleanthous, Sheena E Radford, David J Brockwell
Publicado 2013

Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM

por Matthew G. Iadanza, Anna J. Higgins, Bob Schiffrin, Antonio N. Calabrese, David J. Brockwell, Alison E. Ashcroft, Sheena E. Radford, Neil A. Ranson
Publicado 2016

Distortion of the bilayer and dynamics of the BAM complex in lipid nanodiscs

por Matthew G. Iadanza, Bob Schiffrin, Paul White, Matthew A. Watson, Jim E. Horne, Anna J. Higgins, Antonio N. Calabrese, David J. Brockwell, Roman Tuma, Antreas C. Kalli, Sheena E. Radford, Neil A. Ranson
Publicado 2020

Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients

por Antonio N. Calabrese, Bob Schiffrin, Matthew Watson, Theodoros K. Karamanos, Martin Walko, Julia R. Humes, Jim E. Horne, Paul White, Andrew J. Wilson, Antreas C. Kalli, Roman Tuma, Alison E. Ashcroft, David J. Brockwell, Sheena E. Radford
Publicado 2020

An in vivo platform to select and evolve aggregation-resistant proteins

por Jessica S. Ebo, Janet C. Saunders, Paul W. A. Devine, Alice M. Gordon, Amy S. Warwick, Bob Schiffrin, Stacey E. Chin, Elizabeth England, James D. Button, Christopher Lloyd, Nicholas J. Bond, Alison E. Ashcroft, Sheena E. Radford, David C. Lowe, David J. Brockwell
Publicado 2020

The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding

por Paul White, Samuel F. Haysom, Matthew G. Iadanza, Anna J. Higgins, Jonathan M. Machin, James M. Whitehouse, Jim E. Horne, Bob Schiffrin, Charlotte Carpenter-Platt, Antonio N. Calabrese, Kelly M. Storek, Steven T. Rutherford, David J. Brockwell, Neil A. Ranson, Sheena E. Radford
Publicado 2021