Directed evolution of prenylated FMN-dependent Fdc supports efficient in vivo isobutene production

por Annica Saaret, Benoît Villiers, François Stricher, Macha Anissimova, Mélodie Cadillon, Reynard Spiess, Sam Hay, David Leys
Publicado 2021

Mass spectrometry locates local and allosteric conformational changes that occur on cofactor binding

por Rebecca Beveridge, Lukasz G. Migas, Karl A. P. Payne, Nigel S. Scrutton, David Leys, Perdita E. Barran
Publicado 2016

UbiD domain dynamics underpins aromatic decarboxylation

por Stephen A. Marshall, Karl A. P. Payne, Karl Fisher, Gabriel R. Titchiner, Colin Levy, Sam Hay, David Leys
Publicado 2021

Zymophore identification enables the discovery of novel phenylalanine ammonia lyase enzymes

por Nicholas J. Weise, Syed T. Ahmed, Fabio Parmeggiani, James L. Galman, Mark S. Dunstan, Simon J. Charnock, David Leys, Nicholas J. Turner
Publicado 2017

The UbiX flavin prenyltransferase reaction mechanism resembles class I terpene cyclase chemistry

por Stephen A. Marshall, Karl A. P. Payne, Karl Fisher, Mark D. White, Aisling Ní Cheallaigh, Arune Balaikaite, Stephen E. J. Rigby, David Leys
Publicado 2019