USP15-dependent lysosomal pathway controls p53-R175H turnover in ovarian cancer cells

por Achuth Padmanabhan, Nicholes Candelaria, Kwong-Kwok Wong, Bryan C. Nikolai, David M. Lonard, Bert W. O’Malley, JoAnne S. Richards
Publicado 2018

A genome-scale CRISPR Cas9 dropout screen identifies synthetically lethal targets in SRC-3 inhibited cancer cells

por Yosi Gilad, Yossi Eliaz, Yang Yu, Adam M. Dean, San Jung Han, Li Qin, Bert W. O’Malley, David M. Lonard
Publicado 2021

XBP1 links the 12-hour clock to NAFLD and regulation of membrane fluidity and lipid homeostasis

por Huan Meng, Naomi M. Gonzales, David M. Lonard, Nagireddy Putluri, Bokai Zhu, Clifford C. Dacso, Brian York, Bert W. O’Malley
Publicado 2020

Steroid receptor coactivator 3 (SRC-3/AIB1) is enriched and functional in mouse and human Tregs

por Bryan C. Nikolai, Prashi Jain, David L. Cardenas, Brian York, Qin Feng, Neil J. McKenna, Subhamoy Dasgupta, David M. Lonard, Bert W. O’Malley
Publicado 2021

Targeting NSD2-mediated SRC-3 liquid–liquid phase separation sensitizes bortezomib treatment in multiple myeloma

por Jing Liu, Ying Xie, Jing Guo, Xin Li, Jingjing Wang, Hongmei Jiang, Ziyi Peng, Jingya Wang, Sheng Wang, Qian Li, Linquan Ye, Yuping Zhong, Qiguo Zhang, Xiaozhi Liu, David M. Lonard, Jin Wang, Bert W. O’Malley, Zhiqiang Liu
Publicado 2021

Author Correction: The REGγ inhibitor NIP30 increases sensitivity to chemotherapy in p53-deficient tumor cells

por Xiao Gao, Qingwei Wang, Ying Wang, Jiang Liu, Shuang Liu, Jian Liu, Xingli Zhou, Li Zhou, Hui Chen, Linian Pan, Jiwei Chen, Da Wang, Qing Zhang, Shihui Shen, Yu Xiao, Zhipeng Wu, Yiyun Cheng, Geng Chen, Syeda Kubra, Jun Qin, Lan Huang, Pei Zhang, Chuangui Wang, Robb E. Moses, David M. Lonard, Bert W. O’ Malley, Fuad Fares, Bianhong Zhang, Xiaotao Li, Lei Li, Jianru Xiao
Publicado 2020

The REGγ inhibitor NIP30 increases sensitivity to chemotherapy in p53-deficient tumor cells

por Xiao Gao, Qingwei Wang, Ying Wang, Jiang Liu, Shuang Liu, Jian Liu, Xingli Zhou, Li Zhou, Hui Chen, Linian Pan, Jiwei Chen, Da Wang, Qing Zhang, Shihui Shen, Yu Xiao, Zhipeng Wu, Yiyun Cheng, Geng Chen, Syeda Kubra, Jun Qin, Lan Huang, Pei Zhang, Chuangui Wang, Robb E. Moses, David M. Lonard, Bert W. O’ Malley, Fuad Fares, Bianhong Zhang, Xiaotao Li, Lei Li, Jianru Xiao
Publicado 2020